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Does Abciximab and Cefpodoxime interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefpodoxime, and the severity of the interaction is minor. |
Does Abciximab and Cefprozil interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefprozil, and the severity of the interaction is minor. |
Does Abciximab and Cefradine interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefradine, and the severity of the interaction is minor. |
Does Abciximab and Ceftaroline fosamil interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Ceftaroline fosamil, and the severity of the interaction is minor. |
Does Abciximab and Ceftazidime interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Ceftazidime, and the severity of the interaction is minor. |
Does Abciximab and Ceftibuten interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Ceftibuten, and the severity of the interaction is minor. |
Does Abciximab and Ceftizoxime interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Ceftizoxime, and the severity of the interaction is minor. |
Does Abciximab and Ceftobiprole medocaril interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Ceftobiprole medocaril, and the severity of the interaction is minor. |
Does Abciximab and Ceftobiprole interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Ceftobiprole, and the severity of the interaction is minor. |
Does Abciximab and Ceftriaxone interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Ceftriaxone, and the severity of the interaction is minor. |
Does Abciximab and Cefuroxime interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefuroxime, and the severity of the interaction is minor. |
Does Abciximab and Celecoxib interact? | null | Both anticoagulants and non-steroidal anti-inflammatory agents are associated with a risk for bleeding events. Concomitant use of anticoagulants with over-the-counter NSAIDs may significantly increase the risk for gastrointestinal hemorrhage while concomitant use of anticoagulants with acetaminophen may lead to increased risk for general all-site bleeding events. NSAIDs such as ibuprofen are substrates of CYP2C9, which may also interfere with the metabolism of S-warfarin and further increase the risk for warfarin-associated bleeding. In short, The risk or severity of bleeding and hemorrhage can be increased when Celecoxib is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Cemiplimab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Cemiplimab, and the severity of the interaction is minor. |
Does Abciximab and Cephalexin interact? | null | Certain cephalosporins contain a N-methylthiotetrazole ring which is known to inhibit the production of vitamin K-dependent clotting factor and thus, its use can result in a prolonged prothrombin time. Coadministration of cephalosporins with anticoagulant therapies can produce a significant decrease in the therapeutic effect of the anticoagulant, producing dangerous effects. In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Cephalexin, and the severity of the interaction is minor. |
Does Abciximab and Certolizumab pegol interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Certolizumab pegol, and the severity of the interaction is minor. |
Does Abciximab and Cetuximab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Cetuximab is combined with Abciximab, and the severity of the interaction is minor. |
Does Abciximab and Chenodeoxycholic acid interact? | null | Antiplatelet agents may enhance the bleeding risk when administered with cholic acid due to the additive effects of both drugs. In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Chenodeoxycholic acid, and the severity of the interaction is moderate. |
Does Abciximab and Chlorambucil interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Chlorambucil, and the severity of the interaction is minor. |
Does Abciximab and Chloramphenicol interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Chloramphenicol, and the severity of the interaction is minor. |
Does Abciximab and Chlorothiazide interact? | null | The efficacy of oral anticoagulants may be reduced by the concomitant use of thiazide diuretics.2 The evidence for this interaction is conflicting.1 In short, The therapeutic efficacy of Abciximab can be decreased when used in combination with Chlorothiazide, and the severity of the interaction is minor. |
Does Abciximab and Cholic Acid interact? | null | Antiplatelet agents may enhance the bleeding risk when administered with cholic acid due to the additive effects of both drugs. In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Cholic Acid, and the severity of the interaction is moderate. |
Does Abciximab and Choline magnesium trisalicylate interact? | null | Both anticoagulants and non-steroidal anti-inflammatory agents are associated with a risk for bleeding events. Concomitant use of anticoagulants with over-the-counter NSAIDs may significantly increase the risk for gastrointestinal hemorrhage while concomitant use of anticoagulants with acetaminophen may lead to increased risk for general all-site bleeding events. NSAIDs such as ibuprofen are substrates of CYP2C9, which may also interfere with the metabolism of S-warfarin and further increase the risk for warfarin-associated bleeding. In short, The risk or severity of bleeding and hemorrhage can be increased when Salicylic acid is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Choline salicylate interact? | null | .Concurrent use of salicylates and anticoagulants may lead to increased anticoagulant activity and therefore an increased risk of bleeding, due to additive anticoagulant effects. In short, The risk or severity of bleeding can be increased when Choline salicylate is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Cilostazol interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Cilostazol is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Cisplatin interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Cisplatin, and the severity of the interaction is minor. |
Does Abciximab and Citalopram interact? | null | Serotonin is stored within platelets and is released to aggregate platelets during hemostasis for thrombus formation.1,2 Since citalopram is a serotonin reuptake inhibitor, it could decrease the intraplatelet level of serotonin, thus reducing the serotonin-induced amplification of platelet aggregation. Therefore, the concomitant use of citalopram with an antiplatelet agent can aggravate the risk of bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Citalopram, and the severity of the interaction is moderate. |
Does Abciximab and Cladribine interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Cladribine, and the severity of the interaction is minor. |
Does Abciximab and Clofarabine interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Clofarabine, and the severity of the interaction is minor. |
Does Abciximab and Clopidogrel interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Clopidogrel is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Coagulation Factor IX (Recombinant) interact? | null | Blood coagulation factors promote the blood coagulation pathways to ultimately form the insoluble fibrin clot. In contrast, fibrinolytic agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin to break down the insoluble clot [A38173]. Desired procoagulant effects of blood coagulation factors may be reduced with the combination use of fibrinolytic agents. In short, The therapeutic efficacy of Coagulation Factor IX (Recombinant) can be decreased when used in combination with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Coagulation Factor IX Human interact? | null | Blood coagulation factors promote the blood coagulation pathways to ultimately form the insoluble fibrin clot. In contrast, fibrinolytic agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin to break down the insoluble clot [A38173]. Desired procoagulant effects of blood coagulation factors may be reduced with the combination use of fibrinolytic agents. In short, The therapeutic efficacy of Coagulation Factor IX Human can be decreased when used in combination with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Coagulation factor VII human interact? | null | Blood coagulation factors promote the blood coagulation pathways to ultimately form the insoluble fibrin clot. In contrast, fibrinolytic agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin to break down the insoluble clot [A38173]. Desired procoagulant effects of blood coagulation factors may be reduced with the combination use of fibrinolytic agents. In short, The therapeutic efficacy of Coagulation factor VII human can be decreased when used in combination with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Coagulation factor VIIa Recombinant Human interact? | null | Blood coagulation factors promote the blood coagulation pathways to ultimately form the insoluble fibrin clot. In contrast, fibrinolytic agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin to break down the insoluble clot [A38173]. Desired procoagulant effects of blood coagulation factors may be reduced with the combination use of fibrinolytic agents. In short, The therapeutic efficacy of Coagulation factor VIIa Recombinant Human can be decreased when used in combination with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Coagulation factor X human interact? | null | Blood coagulation factors promote the blood coagulation pathways to ultimately form the insoluble fibrin clot. In contrast, fibrinolytic agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin to break down the insoluble clot [A38173]. Desired procoagulant effects of blood coagulation factors may be reduced with the combination use of fibrinolytic agents. In short, The therapeutic efficacy of Coagulation factor X human can be decreased when used in combination with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Collagenase clostridium histolyticum interact? | null | Anticoagulant agents may increase the risk of hemorrhage in patients treated with collagenase clostridium histolyticum. Penile ecchymoses and bleeding/hematoma at the injection site are commonly observed adverse effects of collagenase clostridium histolyticum that may be worsened with the administration of antiplatelet drugs, which can promote bleeding. Recent studies, however, contradict this finding and did not demonstrate at increased incidence of bleeding episodes. Further research is warranted. In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Collagenase clostridium histolyticum, and the severity of the interaction is moderate. |
Does Abciximab and Conjugated estrogens interact? | null | Estrogens activate the coagulation pathway via increasing plasma fibrinogen and the activity of coagulation factors such as factors VII and X. Co-administration of estrogens with anticoagulant agents may interfere with the anticoagulant actions of those agents. In short, Conjugated estrogens may decrease the anticoagulant activities of Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Cyclophosphamide interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Cyclophosphamide, and the severity of the interaction is minor. |
Does Abciximab and Cyproterone acetate interact? | null | Oral contraceptives may increase blood clotting factors and decrease the effectiveness of anticoagulants due to their prothrombotic effects.1,2,4 In contrast, in some patients anticoagulant effects may actually be potentiated by the use of oral contraceptives, although this risk appears to be relatively low. In short, The risk or severity of adverse effects can be increased when Cyproterone acetate is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Cytarabine interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Cytarabine, and the severity of the interaction is minor. |
Does Abciximab and Dabigatran etexilate interact? | null | Dabigatran etexilate is an anticoagulant agent that may create a synergistic effect when co-administered with other anticoagulant drugs. This may significantly increase the anticoagulant actions of the drugs and the risk of nonfatal bleeding or serious, potentially fatal bleeding associated with that drug class. In short, Dabigatran etexilate may increase the anticoagulant activities of Abciximab, and the severity of the interaction is major. |
Does Abciximab and Dacarbazine interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Dacarbazine, and the severity of the interaction is minor. |
Does Abciximab and Dactinomycin interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Dactinomycin, and the severity of the interaction is minor. |
Does Abciximab and Dalteparin interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Dalteparin, and the severity of the interaction is moderate. |
Does Abciximab and Damoctocog alfa pegol interact? | null | Blood coagulation factors promote the blood coagulation pathways to ultimately form the insoluble fibrin clot. In contrast, fibrinolytic agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin to break down the insoluble clot [A38173]. Desired procoagulant effects of blood coagulation factors may be reduced with the combination use of fibrinolytic agents. In short, The therapeutic efficacy of Damoctocog alfa pegol can be decreased when used in combination with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Danaparoid interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Danaparoid, and the severity of the interaction is moderate. |
Does Abciximab and Daratumumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Daratumumab, and the severity of the interaction is minor. |
Does Abciximab and Dasatinib interact? | null | Bleeding events arising from drug-induced thrombocytopenia, including CNS and gastrointestinal hemorrhages, have occurred with dasatinib therapy. Co-administering dasatinib with other agents with potential to cause bleeding, such as anticoagulants, may significantly increase the risk for both non-fatal and fatal bleeding and haemorrhages. In short, The risk or severity of bleeding and hemorrhage can be increased when Dasatinib is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Daunorubicin interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Daunorubicin, and the severity of the interaction is minor. |
Does Abciximab and Decitabine interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Decitabine, and the severity of the interaction is minor. |
Does Abciximab and Deferasirox interact? | null | Incidences of fatal gastrointestinal hemorrhage have been reported in patients undergoing deferasirox therapy. This risk for this adverse reaction is especially high in elderly patients who had advanced hematologic malignancies and/or low platelet counts. Co-administration of deferasirox with other agents known to affect hemostasis or cause bleeding and hemorrhage, such as anticoagulants, may lead to increased risk for non-fatal and fatal gastrointestinal ulceration and hemorrhage. In short, The risk or severity of gastrointestinal bleeding can be increased when Abciximab is combined with Deferasirox, and the severity of the interaction is moderate. |
Does Abciximab and Defibrotide interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Defibrotide, and the severity of the interaction is moderate. |
Does Abciximab and Denosumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Denosumab, and the severity of the interaction is minor. |
Does Abciximab and Deoxycholic acid interact? | null | Antiplatelet agents may enhance the bleeding risk when administered with cholic acid due to the additive effects of both drugs. In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Deoxycholic acid, and the severity of the interaction is moderate. |
Does Abciximab and Desogestrel interact? | null | Oral contraceptives may increase blood clotting factors and decrease the effectiveness of anticoagulants due to their prothrombotic effects.1,2,4 In contrast, in some patients anticoagulant effects may actually be potentiated by the use of oral contraceptives, although this risk appears to be relatively low. In short, The risk or severity of adverse effects can be increased when Desogestrel is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Desvenlafaxine interact? | null | Serotonin is stored within platelets and is released to aggregate platelets during hemostasis for thrombus formation.1,2 Since desvenlafaxine is a serotonin reuptake inhibitor, it could decrease the intraplatelet level of serotonin, thus reducing the serotonin-induced amplification of platelet aggregation. This results in frequently observed abnormalities in hemostasis associated with antidepressants used. Combining desvenlafaxine with another antiplatelet agent can therefore increase the risk of bleeding. In short, The risk or severity of bleeding can be increased when Desvenlafaxine is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Dexibuprofen interact? | null | Concomitant use of antiplatelet and non-steroidal anti-inflammatory agents (NSAIDs) is associated with increased risk of gastrointestinal bleeding. In short, The risk or severity of bleeding can be increased when Dexibuprofen is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Dexketoprofen interact? | null | Both anticoagulants and non-steroidal anti-inflammatory agents are associated with a risk for bleeding events. Concomitant use of anticoagulants with over-the-counter NSAIDs may significantly increase the risk for gastrointestinal hemorrhage while concomitant use of anticoagulants with acetaminophen may lead to increased risk for general all-site bleeding events. NSAIDs such as ibuprofen are substrates of CYP2C9, which may also interfere with the metabolism of S-warfarin and further increase the risk for warfarin-associated bleeding. In short, The risk or severity of bleeding and hemorrhage can be increased when Dexketoprofen is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Dexrazoxane interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Dexrazoxane, and the severity of the interaction is minor. |
Does Abciximab and Dextran interact? | null | During the EPIC trial, in the 11 patients who received intravenous low molecular weight dextran with abciximab, five had major bleeding events and four had minor bleeding events . None of the five placebo patients treated with low molecular weight dextran and no abciximab had a major or minor bleeding event . In short, Dextran may increase the anticoagulant activities of Abciximab, and the severity of the interaction is major. |
Does Abciximab and Diclofenac interact? | null | Both anticoagulants and non-steroidal anti-inflammatory agents are associated with a risk for bleeding events. Concomitant use of anticoagulants with over-the-counter NSAIDs may significantly increase the risk for gastrointestinal hemorrhage while concomitant use of anticoagulants with acetaminophen may lead to increased risk for general all-site bleeding events. NSAIDs such as ibuprofen are substrates of CYP2C9, which may also interfere with the metabolism of S-warfarin and further increase the risk for warfarin-associated bleeding. In short, The risk or severity of bleeding and hemorrhage can be increased when Diclofenac is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Dienogest interact? | null | Oral contraceptives may increase blood clotting factors and decrease the effectiveness of anticoagulants due to their prothrombotic effects.1,2,4 In contrast, in some patients anticoagulant effects may actually be potentiated by the use of oral contraceptives, although this risk appears to be relatively low. In short, The risk or severity of adverse effects can be increased when Dienogest is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Diflunisal interact? | null | Both anticoagulants and non-steroidal anti-inflammatory agents are associated with a risk for bleeding events. Concomitant use of anticoagulants with over-the-counter NSAIDs may significantly increase the risk for gastrointestinal hemorrhage while concomitant use of anticoagulants with acetaminophen may lead to increased risk for general all-site bleeding events. NSAIDs such as ibuprofen are substrates of CYP2C9, which may also interfere with the metabolism of S-warfarin and further increase the risk for warfarin-associated bleeding. In short, The risk or severity of bleeding and hemorrhage can be increased when Diflunisal is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Digoxin Immune Fab (Ovine) interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Digoxin Immune Fab (Ovine), and the severity of the interaction is minor. |
Does Abciximab and Dinutuximab interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Dinutuximab, and the severity of the interaction is minor. |
Does Abciximab and Dipyridamole interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Dipyridamole, and the severity of the interaction is moderate. |
Does Abciximab and Docetaxel interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Docetaxel, and the severity of the interaction is minor. |
Does Abciximab and Dostarlimab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Dostarlimab, and the severity of the interaction is minor. |
Does Abciximab and Doxorubicin interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Doxorubicin, and the severity of the interaction is minor. |
Does Abciximab and Doxycycline interact? | null | There have been reports of prolonged prothrombin time in patients taking warfarin and doxycycline, increasing the risk of bleeding events. This is due to the fact that doxycycline has been shown to inhibit plasma prothrombin activity. In short, The risk or severity of bleeding can be increased when Doxycycline is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Drospirenone interact? | null | Oral contraceptives may increase blood clotting factors and decrease the effectiveness of anticoagulants due to their prothrombotic effects.1,2,4 In contrast, in some patients anticoagulant effects may actually be potentiated by the use of oral contraceptives, although this risk appears to be relatively low. In short, The risk or severity of adverse effects can be increased when Drospirenone is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Dulaglutide interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Dulaglutide, and the severity of the interaction is minor. |
Does Abciximab and Duloxetine interact? | null | It has been reported that concomitant administration of antiplatelet agents and SSRI is associated with an increase in hemorrhage. This interaction is due to the inhibition of serotonin reuptake in platelets which produces a reduction of serotonin to even 1% of the normal quantity. Serotonin is very important for the aggregation of platelets and the lack of serotonin does not allow the normal aggregation process of the platelets. In short, The risk or severity of hemorrhage can be increased when Duloxetine is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Dupilumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Dupilumab, and the severity of the interaction is minor. |
Does Abciximab and Durvalumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Durvalumab, and the severity of the interaction is minor. |
Does Abciximab and Dydrogesterone interact? | null | Progestins affect hemostasis by exerting a procoagulant activity and are associated with a risk for thromboembolic disorders. While there is limited clinical evidence that progestins may interfere with the pharmacological activity of anticoagulants when co-administered, concurrent use of progestins with anticoagulants may potentially interfere with the anticoagulant actions. In short, Dydrogesterone may decrease the anticoagulant activities of Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Ebola Zaire vaccine (live, attenuated) interact? | null | Immunoglobulins suppress the immune response and may reduce the therapeutic effectiveness of live attenuated Ebola vaccine virus when co-administered in a short time frame, as vaccines work by eliciting an immune response. It is speculated that administration of immune globulins administered 3 months before or up to 1 month after the Ebola virus vaccine administration may interfere with the expected immune response. There is also a possibility of an infection, as live vaccines hold viral proteins and carry a risk of systemic infection, especially to individuals with profound immunosuppression caused by disease or drugs. In short, The therapeutic efficacy of Ebola Zaire vaccine (live, attenuated) can be decreased when used in combination with Abciximab, and the severity of the interaction is minor. |
Does Abciximab and Eculizumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Eculizumab, and the severity of the interaction is minor. |
Does Abciximab and Edetic acid interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Edetic acid, and the severity of the interaction is moderate. |
Does Abciximab and Edoxaban interact? | null | Edoxoaban is associated with a risk for serious bleeding, including serious and fatal bleeding events. Concomitant use of edoxoban with drugs affecting hemostasis, including other anticoagulant drugs, may increase the anticoagulant effect of those drugs due to an additive effect and increase the risk of bleeding. In short, The risk or severity of bleeding can be increased when Edoxaban is combined with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Eflapegrastim interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Eflapegrastim, and the severity of the interaction is minor. |
Does Abciximab and Eftrenonacog alfa interact? | null | Blood coagulation factors promote the blood coagulation pathways to ultimately form the insoluble fibrin clot. In contrast, fibrinolytic agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin to break down the insoluble clot [A38173]. Desired procoagulant effects of blood coagulation factors may be reduced with the combination use of fibrinolytic agents. In short, The therapeutic efficacy of Eftrenonacog alfa can be decreased when used in combination with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Elotuzumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Elotuzumab, and the severity of the interaction is minor. |
Does Abciximab and Emapalumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Emapalumab, and the severity of the interaction is minor. |
Does Abciximab and Emicizumab interact? | null | Blood coagulation factors promote the blood coagulation pathways to ultimately form the insoluble fibrin clot. In contrast, fibrinolytic agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin to break down the insoluble clot [A38173]. Desired procoagulant effects of blood coagulation factors may be reduced with the combination use of fibrinolytic agents. In short, The therapeutic efficacy of Emicizumab can be decreased when used in combination with Abciximab, and the severity of the interaction is major. |
Does Abciximab and Enoxaparin interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Enoxaparin, and the severity of the interaction is moderate. |
Does Abciximab and Epirubicin interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Epirubicin, and the severity of the interaction is minor. |
Does Abciximab and Epoprostenol interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Epoprostenol, and the severity of the interaction is moderate. |
Does Abciximab and Eptifibatide interact? | null | Both antiplatelet agents and anticoagulants are associated with a risk of bleeding when administered alone. The concomitant use of these agents may further increase the risk for fatal and non-fatal bleeding events, including gastrointestinal hemorrhage. In short, The risk or severity of bleeding can be increased when Eptifibatide is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Eptinezumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Eptinezumab, and the severity of the interaction is minor. |
Does Abciximab and Erenumab interact? | null | Biologic therapies carry a risk of immunogenicity which can produce a wide array of adverse effects the most serious of which include anaphylaxis and serum sickness-type reactions . Use of multiple immunoglobulin-based therapies may increase the risk of these immunological complications. A few studies suggest the use of multiple immunoglobulin agents is relatively safe and may be more effective than monotherapy for certain conditions . In short, The risk or severity of adverse effects can be increased when Abciximab is combined with Erenumab, and the severity of the interaction is minor. |
Does Abciximab and Eribulin interact? | null | As their name suggested, myelosuppressive agents can decrease the production of cells found in the bone marrow, including thrombocytes.5,1 Low levels of thrombocytes, or thrombocytopenia, can increase the risk of bleeding due to the inability to form blood clots. Therefore, concomitant administration of agents that prevent thrombotic events such as antiplatelet agents can further exacerbate this risk into abnormal bleeding. In short, The risk or severity of bleeding can be increased when Abciximab is combined with Eribulin, and the severity of the interaction is minor. |
Does Abciximab and Erythromycin interact? | null | Erythromycin may increase the bleeding tendency associated with anticoagulant agents, according to several reports.1,3,2,6 The mechanism behind this interaction is likely the fact that erythromycin is a CYP3A4 inhibitor which may decrease the metabolism of various anticoagulants, potentiating their bleeding risk. In short, The risk or severity of bleeding can be increased when Erythromycin is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Escitalopram interact? | null | Platelets release serotonin in response to injury, triggering vasoconstriction and eventually hemostasis. As a selective serotonin re-uptake inhibitor (SSRI), escitalopram can inhibit the re-uptake of serotonin into platelets in much the same way it inhibits re-uptake into pre-synaptic neurons - this decrease in available platelet serotonin can result in a diminished clotting response and increased risk of bleeding. The combination of escitalopram with other agents that can increase the risk of bleeding may potentiate the baseline risk associated with SSRI use. SSRIs may also affect clotting ability via action the glycogen IIb/IIIa surface receptor (involved in platelet aggregation) or up-regulation of glycogen synthase kinase 3-beta (GSK3B) on platelets. In short, The risk or severity of bleeding can be increased when Escitalopram is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Esterified estrogens interact? | null | Estrogens activate the coagulation pathway via increasing plasma fibrinogen and the activity of coagulation factors such as factors VII and X. Co-administration of estrogens with anticoagulant agents may interfere with the anticoagulant actions of those agents. In short, Esterified estrogens may decrease the anticoagulant activities of Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Estradiol acetate interact? | null | Estrogens activate the coagulation pathway via increasing plasma fibrinogen and the activity of coagulation factors such as factors VII and X. Co-administration of estrogens with anticoagulant agents may interfere with the anticoagulant actions of those agents. In short, Estradiol acetate may decrease the anticoagulant activities of Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Estradiol benzoate interact? | null | Estrogens activate the coagulation pathway via increasing plasma fibrinogen and the activity of coagulation factors such as factors VII and X. Co-administration of estrogens with anticoagulant agents may interfere with the anticoagulant actions of those agents. In short, Estradiol benzoate may decrease the anticoagulant activities of Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Estradiol cypionate interact? | null | Estrogens activate the coagulation pathway via increasing plasma fibrinogen and the activity of coagulation factors such as factors VII and X. Co-administration of estrogens with anticoagulant agents may interfere with the anticoagulant actions of those agents. In short, Estradiol cypionate may decrease the anticoagulant activities of Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Estradiol valerate interact? | null | Estrogens activate the coagulation pathway via increasing plasma fibrinogen and the activity of coagulation factors such as factors VII and X. Co-administration of estrogens with anticoagulant agents may interfere with the anticoagulant actions of those agents. In short, Estradiol valerate may decrease the anticoagulant activities of Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Estradiol interact? | null | Oral contraceptives may increase blood clotting factors and decrease the effectiveness of anticoagulants due to their prothrombotic effects.1,2,4 In contrast, in some patients anticoagulant effects may actually be potentiated by the use of oral contraceptives, although this risk appears to be relatively low. In short, The risk or severity of adverse effects can be increased when Estradiol is combined with Abciximab, and the severity of the interaction is moderate. |
Does Abciximab and Estriol interact? | null | Estrogens activate the coagulation pathway via increasing plasma fibrinogen and the activity of coagulation factors such as factors VII and X. Co-administration of estrogens with anticoagulant agents may interfere with the anticoagulant actions of those agents. In short, Estriol may decrease the anticoagulant activities of Abciximab, and the severity of the interaction is moderate. |