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GuideRNA-3B

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license: apache-2.0
tags:
  - biology
size_categories:
  - 1B<n<10B

Dataset Card for GuideRNA-3B

Dataset Description

Dataset Summary

GuideRNA-3B is a large transcriptome sequence corpus consisting of over 3.7 billion paired sequences extracted from the specific transcriptome of 23 cell lines and over 200 segmented genomes of RNA virus.

Supported Tasks

Based on this nucleotide sequence corpus, we are able to establish a foundation model to characterize the manifold of CRISPR guide RNA targeting regions in order to undertake further downstreaming task for universal CRISPR-based RNA virus amplification-free detection and inhibition. For details, please refer to our paper and website.

Languages

English (en).

Dataset Structure

jsonl-based Arrow

These files are compressed Arrow-formated sourced from JSON-lined text file data, with the following columns:

  • before: string. Nucleotide sequence from transcriptome of cell line or RNA virus.
  • next: string. Nucleotide sequence with postion right-shifted by one.

Citation Information

If you find GuideRNA-3B helpful in your research, please cite our work by: