lamhieu/medical_advice_dialogue_en · Datasets at Hugging Face

messages listlengths 2 2
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThis supports a potential additive benefit of statins in the inflammatory state of ACS and reaffirms the clinical importance of statin therapy for coronary atherosclerosis.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThese results highlight that skeletal muscle measurements from CT images obtained in the course of care can improve the precision of aminoglycoside CL estimation over current body size scalars.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe patients tolerate the PTCA procedure very well under the assistance of intra-aortic balloon counterpulsation (IABP) even in very severe condition.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nWithin the framework of inpatient psychosomatic treatment involving a psychotherapeutic treatment setting, substitution facilitates weight gain.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe early results of this WoA Epic pilot trial did not support the suggestion that patients receiving the SJEP, and tissue valves in general, should be administered warfarin to prevent valve thrombosis and peripheral arterial embolic phenomena.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThis relationship may potentially be explained by BMI tracking, which has been demonstrated from infancy to middle childhood44. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nPattern may also be important since no clinical investigations of negative feedback have yet attempted to emulate a physiological train of cortisol pulses (citation). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nPatients treated with clindamycin and those with a peripherally inserted central catheter had higher rates of unplanned outpatient visits.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAmong a plethora of CIN definitions—also including general definitions of acute renal impairment such as RIFLE, AKIN, and KDIGO—this definition was chosen for several reasons. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSTAT4 is a transcription factor belonging to STAT family23, important members of Janus Kinase (JAK)-STAT pathway, that is required for the development of Th1 cells from naïve CD4+ T cells24 and interferon-γ (IFN-γ) production in response to interleukin-12 (IL12)25 and type I interferon (IFN-α or IFN-β)26. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOn the other hand, several studies have reported that laparoscopic surgery may be more painful because of the greater abdominal wall injury than robotic surgery. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTherefore, an ASY arm crank configuration should be used to assess anaerobic power in most individuals although specific population groups may require further testing.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe patient P9 could possibly be linked to this outbreak via hospital H. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nMeintjes et al. [19] also observed that human embryos cultured in 5% oxygen consistently yield better clinical results in a fresh blastocyst-transfer (BT) program. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nArterial stiffness was improved by vitamin D3 supplementation in a dose-response manner in overweight African Americans with vitamin D deficiency.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt is concluded that oral NaAcetate could be used as both an alkalinizing agent and an alternative energy source in the horse.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBecause most current chemotherapeutic agents are cytotoxic and cause many side effects, chemotherapy cannot be used during surgical resection to prevent cancer recurrence. ", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTeletriage callers were confident in the advice provided and were willing to continue to use the service.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBetween January 1987 and December 1998, we treated 867 patients suffering from primary solid malignant tumours. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe proportion of ECPs in the current study was lower than among Spanish elderly individuals with increased risk for cardiovascular diseases [10], US adults who were mostly females and well educated [6] and among US adults who had hypercholesterolemia [9]. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nExercise behavior in lymphoma patients 6 months after a randomized trial was predicted by a wide range of demographic, medical, health-related fitness, quality of life, and motivational variables.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nImpaired renal function and all defined types of renal impairment have been shown to worsen the long-term prognosis of AMI patients treated with PCI.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAlthough we did not measure miRNA expression levels by lutein/zeaxanthin intake, our study supports the notion that dietary lutein/zeaxanthin intake impacts DICER1 activity by regulating miRNA expression, thus affecting CRC risk via an underlying interaction between antioxidant effects and miRNA expression. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAripiprazole can be used safely in combination with SSRIs that have a CYP enzyme-inhibitory action.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt may be attributed to the frontal-subcortical circuitry dysfunction.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nWhile the exact functional relationship of this is unclear, the ability to search visual information is a prerequisite for learning involved in language and cognition, and the optic radiation is one of the first white matter tracts to be myelinated during infancy. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nGenerally, sharing controls is likely to work well when strict frequency matching is not required and there is a large overlap of interview questions, other data to be collected, and eligibility criteria among the studies.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBecause patients underwent cardiac surgery on the beating heart, these results could have implications for cardiac patients undergoing noncardiac surgery.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nDespite confounding effects by factors such as gestational age at birth, these correlations remain significant in many brain white matter regions. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nDespite this uncertainty, this report clearly establishes a congenital myasthenic syndrome as a new allelic disorder to be grouped with the myotonias and periodic paralyses previously attributed to mutations in Nav1.4. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAll impressions from self-reporting were positive such as relaxed, comfortable, and enjoyable by the aromatherapy group.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAlthough the superiority of the LCD disappeared 1 year after the intensive intervention, these data suggest that well-constructed nutrition therapy programs, both CRD and LCD, were equally effective in improving HbA1c for at least 1 year.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBoth symptoms and QoL improved significantly in patients with PersAF after ablation.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAlthough screen failures in the form of diagnostic false negatives occur within the Finnish screening program, their effect on cancer incidence is fairly small and cannot be readily decreased without sacrificing the high specificity of screening or without high incremental costs.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nA minority modified their diving practices to mitigate the risk of their condition and approximately half sought specialist diving medical advice.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSeveral studies have identified that a loss of Dicer contributes to tumorigenesis progression via DNA damage69,70. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe present meta-analysis confirms and reinforces the evidence of a diabetogenic effect by statins utilization.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nRecent genome-wide associated studies (GWASs) have revealed several common loci associated with the risk of hepatitis B virus (HBV)- or hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSafe, feasible, and effective strategies to reduce both HbA1c and perioperative hyperglycemia need to be developed to optimize patient outcomes.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nHome-based strategies could be a promising component of poverty alleviation programmes seeking to improve developmental outcomes among rural Peruvian children.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTrial registration NCT01267097; clinicaltrials.gov.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAt present there are no data available in literature or specific trials evaluating the possible correlation between liver tests abnormalities of trabectedin and its efficacy in the treatment of STS, in terms of PFS and OS, which represents a strength of this study. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThese results do not support the addition of 10 microg ITS to 0.4 mg ITM for colorectal surgery, as low dose sufentanil does not improve intraoperative and postoperative analgesia in this setting.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn the course of PEEP titration, oxygenation in the PEEP-ventilated patients improved in some specific levels. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTherefore it should be used with caution.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nPapacarie(\\xc2\\xae) is an excellent option for the minimally invasive removal of carious tissue, achieving significant reductions in total bacteria, total Streptococcus and S. mutans with the same effectiveness as the traditional caries removal method.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nNon-pharmacological interventions are also initiated before LSS and are continued long-term (Anghelescu, Oakes, & Popenhagen, 2006; Berde, Lebel, & Olsson, 2003). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThus, it is apparent that the incidence and prevalence of bone metastases are difficult to determine with accuracy, and there are no studies concerning the incidence of bone metastasis as the first sign of generalised metastatic disease. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt is not possible to estimate absolute risk of VTE among women with both of these risk factors; however, the absolute risk of VTE in healthy women of reproductive age is small.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSince the GRS63 was clearly associated with fracture risk in non-BMD adjusted models and marginally associated with fracture risk in BMD-adjusted models, we next evaluated its clinical usefulness for fracture discrimination and reclassification in models with or without BMD included. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSuch youth may require interventions targeting depression.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nGTF is well tolerated and helps with catch-up growth and puberty.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nA low threshold for performing preoperative imaging in patients with AMD, especially in those with exudative AMD in the fellow eye, to exclude undetected CNV is recommended.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nHowever, a careful gross description is still necessary in certain cases for potential future medicolegal implications.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe findings in this study were consistent with those in a previous study that reported fatalist attitudes are prevalent and fear of cancer is frequent among those who live in lower socioeconomic conditions (Byrne, 2009). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nParticipants in Oxford House share their background, discuss drug histories, talk about personal and group goals, eat together, engage in chores, and attend 12-step meetings and go on other outings with one another (Olson et al, 2005). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSimilarly, both rs3803300 GG genotype and G allele had obvious differences between case and control groups (P\\u200a<\\u200a.05) and it was closely associated with CHD susceptibility. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAmong them, MTAP, CDKN2A and ARNT/SETDB1 were also identified by eQTL and chromatin interaction mapping approaches in FUMA, and MC1R, TERT and OCA2 were also prioritized by the eQTL mapping approach to be potential causal or functional genes for melanoma development with FUMA. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAdditionally, we measured seminal plasma HIV-1 RNA and did not quantify cell-associated virus. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn concordance with the apoptosis rate, we observed a fourfold increase of caspase-3 activation in RTCs, which was associated with a higher extent of apoptotic death. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nRadiographic scoring at each time interval showed reduction in both number of nodules (P = \\u200a<0.0001) and largest nodule diameter (P =\\u200a <0.0001) in all patients for at least 18 months following B cell depletion. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThese findings challenge the translatability of systemic TNFR1 and TNFR2 from their strong role as biomarkers to a potential role as therapeutic targets. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nHowever, although patients with pre-existing osteopenia are likely to require monitoring and bone-protection strategies, patients with normal BMD would not appear to require monitoring beyond the recommendation for healthy postmenopausal women.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nStrategies to encourage weight loss may need to be considered seriously prior to open ventral hernia repair, especially for patients with body mass index >40\\xa0kg/m2.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nFormal nutritional assessment, however, is inadequate.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nArrangements for routine enterovirus diagnostic typing are also highly variable [5,6]. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nNonetheless, the high mortality due to violence is a warning sign.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nPatients with A-T decline in growth over time.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe association between cognitive function and these two loci as well as PICALM was examined in 1,666 subjects enrolled in the Religious Orders Study (ROS) and in the Rush Memory and Aging Project (MAP). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThis general reduction in the size of the CC except for the rostrum was thought to be the result of cortical atrophy secondary to the disease.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nWe found an SVR to reduce overall mortality and risk of death from liver-related and non-liver-related causes.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe improved sensory nerve function observed after 12 weeks of therapy was maintained at 60 weeks, and improved motor nerve function was observed at 60 weeks.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt leads to a sustained improvement/resolution of OAC, and although weight loss is not continuous, it is maintained over time.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn conclusion, this case-control study performed in Slovak population does not provide further evidence for recently formulated concept that MCP-1 −2518 A/G SNP is involved in the genetic predisposition to systemic sclerosis as a whole. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAmong the vascular adhesion molecules, E-selectin is essential for recruitment of inflammatory cells to damaged tissues (31), and it enables circulating tumor cells to roll and tether on the endothelium. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn the limited number of cases in this cohort with JRA-associated ophthalmologic complications there was no resulting loss of visual acuity.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAPBI in Japanese women provides satisfactory clinical results except for cosmetic outcomes.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOne hundred fifty patients underwent 151 limb-salvage surgeries for bone cancer of the extremities in this series. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\npalpation and Johnson's technique can be used as alternatives to ultrasound for EFW, particularly if the measurements are taken by experienced, skilled personnel.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAlso in 2015, an E. coli ST410 isolate harboring blaCTX-M-15 and blaCMY-2 and carrying blaOXA-181 on an ~48.5-kb plasmid and blaNDM-5 on an ~100-kb plasmid together with FIA and FIB replicons was reported in a study from Egypt (20). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTerry et al. [18] found that a later age at menarche was associated with higher genomic global methylation later on in adulthood, but DNA methylation was only assessed in 92 individuals and the authors used a different technique for measuring global methylation ([3H]-methyl acceptance assay). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe effect of fasting on glucose was small and may not be clinically important.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAdditional therapy may be necessary to enhance long-term results.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOur study demonstrates that live 3DE, easily performed at the bedside, provides incremental information on patients with a variety of congenital heart lesions.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOf 27 patients with partial GHD after pituitary surgery, 40.7% developed severe GHD and 25.9% normalized their GH response.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBody weight was only a marginal factor in this estimate, as CrCL determined without using weight still explained 21% of the variability in this parameter. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nWhile TNF causes NF-κB activation in Caco-2 cells and macrophages, the discrepant effect of TNF on ABCA1 expression (upregulated in macrophages and downregulated in Caco-2) suggests that mechanisms other than NF-κB may modulate ABCA1 expression (53). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nA low oxygen concentration significantly improves the developmental potential of pre-compaction stage embryos, resulting in a positive effect on subsequent blastocyst cultivation. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThese results indicate that the application of IPC can be considered as an effective method to prevent deep vein thrombosis for immobile patients with brain injury.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOver half of ETC + navigation participants did not receive the minimum intervention dose. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nMoreover, the strong associations of the stable high BMIz and rapid BMIz gain trajectories with increased adiposity and obesity risk observed in our study were in line with recent findings17, 18, also suggesting the robustness of our study findings. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe Li maneuver is a rapid, simple and efficacious repositioning method for geotropic HC-BPPV and can be widely applied in clinical practice as an alternative method.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nFuture studies also might focus on considering whether the changes in tolerance found in the present study buffered against stigma and, in turn, led to more positive health and social outcomes. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn addition, no difference in plasma angiogenin levels was found between patients with inflammatory joint disease and those with OA. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt underscores the need of involving parents in youth alcohol prevention programs, and the need to target both parents and adolescents, so that change in parents' behavior enables change in their offspring.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nErlotinib plus bevacizumab and panitumumab is an efficient second-line treatment option for patients with NSCLC.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn a recent study in IBS-D patients who had previously responded to gluten withdrawal, there was no difference in symptom generation after gluten exposure on the basis of HLA-DQ2/8 status (4). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nNegative social interactions and social integration should be investigated in assessments and interventions intended to target caregiver depressive symptom levels.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThis technique may offer anesthesiologists prospects for establishing a better, direct assessment of the patient–ventilator interaction and a more protective mechanical ventilation protocol.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]
[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn this cohort, hypertension and haematuria were prevalent while renal disease was rare.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThis supports a potential additive benefit of statins in the inflammatory state of ACS and reaffirms the clinical importance of statin therapy for coronary atherosclerosis.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThese results highlight that skeletal muscle measurements from CT images obtained in the course of care can improve the precision of aminoglycoside CL estimation over current body size scalars.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe patients tolerate the PTCA procedure very well under the assistance of intra-aortic balloon counterpulsation (IABP) even in very severe condition.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nWithin the framework of inpatient psychosomatic treatment involving a psychotherapeutic treatment setting, substitution facilitates weight gain.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe early results of this WoA Epic pilot trial did not support the suggestion that patients receiving the SJEP, and tissue valves in general, should be administered warfarin to prevent valve thrombosis and peripheral arterial embolic phenomena.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThis relationship may potentially be explained by BMI tracking, which has been demonstrated from infancy to middle childhood44. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nPattern may also be important since no clinical investigations of negative feedback have yet attempted to emulate a physiological train of cortisol pulses (citation). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nPatients treated with clindamycin and those with a peripherally inserted central catheter had higher rates of unplanned outpatient visits.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAmong a plethora of CIN definitions—also including general definitions of acute renal impairment such as RIFLE, AKIN, and KDIGO—this definition was chosen for several reasons. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSTAT4 is a transcription factor belonging to STAT family23, important members of Janus Kinase (JAK)-STAT pathway, that is required for the development of Th1 cells from naïve CD4+ T cells24 and interferon-γ (IFN-γ) production in response to interleukin-12 (IL12)25 and type I interferon (IFN-α or IFN-β)26. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOn the other hand, several studies have reported that laparoscopic surgery may be more painful because of the greater abdominal wall injury than robotic surgery. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTherefore, an ASY arm crank configuration should be used to assess anaerobic power in most individuals although specific population groups may require further testing.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe patient P9 could possibly be linked to this outbreak via hospital H. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nMeintjes et al. [19] also observed that human embryos cultured in 5% oxygen consistently yield better clinical results in a fresh blastocyst-transfer (BT) program. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nArterial stiffness was improved by vitamin D3 supplementation in a dose-response manner in overweight African Americans with vitamin D deficiency.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt is concluded that oral NaAcetate could be used as both an alkalinizing agent and an alternative energy source in the horse.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBecause most current chemotherapeutic agents are cytotoxic and cause many side effects, chemotherapy cannot be used during surgical resection to prevent cancer recurrence. ", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTeletriage callers were confident in the advice provided and were willing to continue to use the service.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBetween January 1987 and December 1998, we treated 867 patients suffering from primary solid malignant tumours. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe proportion of ECPs in the current study was lower than among Spanish elderly individuals with increased risk for cardiovascular diseases [10], US adults who were mostly females and well educated [6] and among US adults who had hypercholesterolemia [9]. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nExercise behavior in lymphoma patients 6 months after a randomized trial was predicted by a wide range of demographic, medical, health-related fitness, quality of life, and motivational variables.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nImpaired renal function and all defined types of renal impairment have been shown to worsen the long-term prognosis of AMI patients treated with PCI.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAlthough we did not measure miRNA expression levels by lutein/zeaxanthin intake, our study supports the notion that dietary lutein/zeaxanthin intake impacts DICER1 activity by regulating miRNA expression, thus affecting CRC risk via an underlying interaction between antioxidant effects and miRNA expression. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAripiprazole can be used safely in combination with SSRIs that have a CYP enzyme-inhibitory action.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt may be attributed to the frontal-subcortical circuitry dysfunction.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nWhile the exact functional relationship of this is unclear, the ability to search visual information is a prerequisite for learning involved in language and cognition, and the optic radiation is one of the first white matter tracts to be myelinated during infancy. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nGenerally, sharing controls is likely to work well when strict frequency matching is not required and there is a large overlap of interview questions, other data to be collected, and eligibility criteria among the studies.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBecause patients underwent cardiac surgery on the beating heart, these results could have implications for cardiac patients undergoing noncardiac surgery.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nDespite confounding effects by factors such as gestational age at birth, these correlations remain significant in many brain white matter regions. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nDespite this uncertainty, this report clearly establishes a congenital myasthenic syndrome as a new allelic disorder to be grouped with the myotonias and periodic paralyses previously attributed to mutations in Nav1.4. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAll impressions from self-reporting were positive such as relaxed, comfortable, and enjoyable by the aromatherapy group.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAlthough the superiority of the LCD disappeared 1 year after the intensive intervention, these data suggest that well-constructed nutrition therapy programs, both CRD and LCD, were equally effective in improving HbA1c for at least 1 year.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBoth symptoms and QoL improved significantly in patients with PersAF after ablation.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAlthough screen failures in the form of diagnostic false negatives occur within the Finnish screening program, their effect on cancer incidence is fairly small and cannot be readily decreased without sacrificing the high specificity of screening or without high incremental costs.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nA minority modified their diving practices to mitigate the risk of their condition and approximately half sought specialist diving medical advice.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSeveral studies have identified that a loss of Dicer contributes to tumorigenesis progression via DNA damage69,70. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe present meta-analysis confirms and reinforces the evidence of a diabetogenic effect by statins utilization.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nRecent genome-wide associated studies (GWASs) have revealed several common loci associated with the risk of hepatitis B virus (HBV)- or hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSafe, feasible, and effective strategies to reduce both HbA1c and perioperative hyperglycemia need to be developed to optimize patient outcomes.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nHome-based strategies could be a promising component of poverty alleviation programmes seeking to improve developmental outcomes among rural Peruvian children.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTrial registration NCT01267097; clinicaltrials.gov.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAt present there are no data available in literature or specific trials evaluating the possible correlation between liver tests abnormalities of trabectedin and its efficacy in the treatment of STS, in terms of PFS and OS, which represents a strength of this study. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThese results do not support the addition of 10 microg ITS to 0.4 mg ITM for colorectal surgery, as low dose sufentanil does not improve intraoperative and postoperative analgesia in this setting.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn the course of PEEP titration, oxygenation in the PEEP-ventilated patients improved in some specific levels. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTherefore it should be used with caution.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nPapacarie(\\xc2\\xae) is an excellent option for the minimally invasive removal of carious tissue, achieving significant reductions in total bacteria, total Streptococcus and S. mutans with the same effectiveness as the traditional caries removal method.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nNon-pharmacological interventions are also initiated before LSS and are continued long-term (Anghelescu, Oakes, & Popenhagen, 2006; Berde, Lebel, & Olsson, 2003). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThus, it is apparent that the incidence and prevalence of bone metastases are difficult to determine with accuracy, and there are no studies concerning the incidence of bone metastasis as the first sign of generalised metastatic disease. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt is not possible to estimate absolute risk of VTE among women with both of these risk factors; however, the absolute risk of VTE in healthy women of reproductive age is small.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSince the GRS63 was clearly associated with fracture risk in non-BMD adjusted models and marginally associated with fracture risk in BMD-adjusted models, we next evaluated its clinical usefulness for fracture discrimination and reclassification in models with or without BMD included. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSuch youth may require interventions targeting depression.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nGTF is well tolerated and helps with catch-up growth and puberty.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nA low threshold for performing preoperative imaging in patients with AMD, especially in those with exudative AMD in the fellow eye, to exclude undetected CNV is recommended.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nHowever, a careful gross description is still necessary in certain cases for potential future medicolegal implications.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe findings in this study were consistent with those in a previous study that reported fatalist attitudes are prevalent and fear of cancer is frequent among those who live in lower socioeconomic conditions (Byrne, 2009). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nParticipants in Oxford House share their background, discuss drug histories, talk about personal and group goals, eat together, engage in chores, and attend 12-step meetings and go on other outings with one another (Olson et al, 2005). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nSimilarly, both rs3803300 GG genotype and G allele had obvious differences between case and control groups (P\\u200a<\\u200a.05) and it was closely associated with CHD susceptibility. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAmong them, MTAP, CDKN2A and ARNT/SETDB1 were also identified by eQTL and chromatin interaction mapping approaches in FUMA, and MC1R, TERT and OCA2 were also prioritized by the eQTL mapping approach to be potential causal or functional genes for melanoma development with FUMA. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAdditionally, we measured seminal plasma HIV-1 RNA and did not quantify cell-associated virus. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn concordance with the apoptosis rate, we observed a fourfold increase of caspase-3 activation in RTCs, which was associated with a higher extent of apoptotic death. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nRadiographic scoring at each time interval showed reduction in both number of nodules (P = \\u200a<0.0001) and largest nodule diameter (P =\\u200a <0.0001) in all patients for at least 18 months following B cell depletion. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThese findings challenge the translatability of systemic TNFR1 and TNFR2 from their strong role as biomarkers to a potential role as therapeutic targets. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nHowever, although patients with pre-existing osteopenia are likely to require monitoring and bone-protection strategies, patients with normal BMD would not appear to require monitoring beyond the recommendation for healthy postmenopausal women.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nStrategies to encourage weight loss may need to be considered seriously prior to open ventral hernia repair, especially for patients with body mass index >40\\xa0kg/m2.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nFormal nutritional assessment, however, is inadequate.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nArrangements for routine enterovirus diagnostic typing are also highly variable [5,6]. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nNonetheless, the high mortality due to violence is a warning sign.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nPatients with A-T decline in growth over time.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe association between cognitive function and these two loci as well as PICALM was examined in 1,666 subjects enrolled in the Religious Orders Study (ROS) and in the Rush Memory and Aging Project (MAP). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThis general reduction in the size of the CC except for the rostrum was thought to be the result of cortical atrophy secondary to the disease.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nWe found an SVR to reduce overall mortality and risk of death from liver-related and non-liver-related causes.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe improved sensory nerve function observed after 12 weeks of therapy was maintained at 60 weeks, and improved motor nerve function was observed at 60 weeks.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt leads to a sustained improvement/resolution of OAC, and although weight loss is not continuous, it is maintained over time.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn conclusion, this case-control study performed in Slovak population does not provide further evidence for recently formulated concept that MCP-1 −2518 A/G SNP is involved in the genetic predisposition to systemic sclerosis as a whole. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAmong the vascular adhesion molecules, E-selectin is essential for recruitment of inflammatory cells to damaged tissues (31), and it enables circulating tumor cells to roll and tether on the endothelium. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn the limited number of cases in this cohort with JRA-associated ophthalmologic complications there was no resulting loss of visual acuity.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAPBI in Japanese women provides satisfactory clinical results except for cosmetic outcomes.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOne hundred fifty patients underwent 151 limb-salvage surgeries for bone cancer of the extremities in this series. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\npalpation and Johnson's technique can be used as alternatives to ultrasound for EFW, particularly if the measurements are taken by experienced, skilled personnel.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAlso in 2015, an E. coli ST410 isolate harboring blaCTX-M-15 and blaCMY-2 and carrying blaOXA-181 on an ~48.5-kb plasmid and blaNDM-5 on an ~100-kb plasmid together with FIA and FIB replicons was reported in a study from Egypt (20). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nTerry et al. [18] found that a later age at menarche was associated with higher genomic global methylation later on in adulthood, but DNA methylation was only assessed in 92 individuals and the authors used a different technique for measuring global methylation ([3H]-methyl acceptance assay). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe effect of fasting on glucose was small and may not be clinically important.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nAdditional therapy may be necessary to enhance long-term results.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOur study demonstrates that live 3DE, easily performed at the bedside, provides incremental information on patients with a variety of congenital heart lesions.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOf 27 patients with partial GHD after pituitary surgery, 40.7% developed severe GHD and 25.9% normalized their GH response.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nBody weight was only a marginal factor in this estimate, as CrCL determined without using weight still explained 21% of the variability in this parameter. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nWhile TNF causes NF-κB activation in Caco-2 cells and macrophages, the discrepant effect of TNF on ABCA1 expression (upregulated in macrophages and downregulated in Caco-2) suggests that mechanisms other than NF-κB may modulate ABCA1 expression (53). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nA low oxygen concentration significantly improves the developmental potential of pre-compaction stage embryos, resulting in a positive effect on subsequent blastocyst cultivation. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThese results indicate that the application of IPC can be considered as an effective method to prevent deep vein thrombosis for immobile patients with brain injury.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nOver half of ETC + navigation participants did not receive the minimum intervention dose. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nMoreover, the strong associations of the stable high BMIz and rapid BMIz gain trajectories with increased adiposity and obesity risk observed in our study were in line with recent findings17, 18, also suggesting the robustness of our study findings. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThe Li maneuver is a rapid, simple and efficacious repositioning method for geotropic HC-BPPV and can be widely applied in clinical practice as an alternative method.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nFuture studies also might focus on considering whether the changes in tolerance found in the present study buffered against stigma and, in turn, led to more positive health and social outcomes. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn addition, no difference in plasma angiogenin levels was found between patients with inflammatory joint disease and those with OA. ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIt underscores the need of involving parents in youth alcohol prevention programs, and the need to target both parents and adolescents, so that change in parents' behavior enables change in their offspring.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nErlotinib plus bevacizumab and panitumumab is an efficient second-line treatment option for patients with NSCLC.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn a recent study in IBS-D patients who had previously responded to gluten withdrawal, there was no difference in symptom generation after gluten exposure on the basis of HLA-DQ2/8 status (4). ", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nNegative social interactions and social integration should be investigated in assessments and interventions intended to target caregiver depressive symptom levels.", "role": "user" }, { "content": "This is a strong advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nThis technique may offer anesthesiologists prospects for establishing a better, direct assessment of the patient–ventilator interaction and a more protective mechanical ventilation protocol.", "role": "user" }, { "content": "This is a weak advice", "role": "assistant" } ]

[ { "content": "Question: is this a 2) strong advice, 1) weak advice 0) no advice?\n\nIn this cohort, hypertension and haematuria were prevalent while renal disease was rare.", "role": "user" }, { "content": "This is no advice", "role": "assistant" } ]