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Enveda Biosciences 2

10072339_1 Facial dermatitis, contact urticaria, rhinoconjunctivitis, and asthma induced by potato.

10072339 0 17 Facial dermatitis Negative_phenotype

10072339 19 36 contact urticaria Negative_phenotype

10072339 38 57 rhinoconjunctivitis Negative_phenotype

10072339 63 69 asthma Negative_phenotype

10072339 81 87 potato Plant

10072339 Increase 0 17 Facial dermatitis Negative_phenotype 81 87 potato Plant

10072339 Increase 19 36 contact urticaria Negative_phenotype 81 87 potato Plant

10072339 Increase 38 57 rhinoconjunctivitis Negative_phenotype 81 87 potato Plant

10072339 Increase 63 69 asthma Negative_phenotype 81 87 potato Plant

10072339_2 BACKGROUND: Potato contains multiple heat-labile proteins which can induce immediate hypersensitivity reactions.

10072339 12 18 Potato Plant

10072339 85 101 hypersensitivity Negative_phenotype

10072339 Increase 12 18 Potato Plant 85 101 hypersensitivity Negative_phenotype

10072339_3 Rhino-conjunctivitis, asthma, contact urticaria and protein contact dermatitis have been described in association with potato exposure.

10072339 0 20 Rhino-conjunctivitis Negative_phenotype

10072339 22 28 asthma Negative_phenotype

10072339 30 47 contact urticaria Negative_phenotype

10072339 52 78 protein contact dermatitis Negative_phenotype

10072339 119 125 potato Plant

10072339 Association 0 20 Rhino-conjunctivitis Negative_phenotype 119 125 potato Plant

10072339 Association 22 28 asthma Negative_phenotype 119 125 potato Plant

10072339 Association 52 78 protein contact dermatitis Negative_phenotype 119 125 potato Plant

10072339_4 OBJECTIVE: A patient with possible airborne facial dermatitis to potato is described.

10072339 44 61 facial dermatitis Negative_phenotype

10072339 65 71 potato Plant

10072339_5 RESULTS: A middle-aged atopic housewife with pre-existent atopic dermatitis suffered from rhino-conjunctivitis, asthma, and contact urticaria when pealing raw potatoes, but her main complaint was intense, treatment-resistant dermatitis of the face.

10072339 23 29 atopic Negative_phenotype

10072339 58 75 atopic dermatitis Negative_phenotype

10072339 90 110 rhino-conjunctivitis Negative_phenotype

10072339 112 118 asthma Negative_phenotype

10072339 124 141 contact urticaria Negative_phenotype

10072339 159 167 potatoes Plant

10072339 225 235 dermatitis Negative_phenotype

10072339 Increase 58 75 atopic dermatitis Negative_phenotype 159 167 potatoes Plant

10072339 Increase 90 110 rhino-conjunctivitis Negative_phenotype 159 167 potatoes Plant

10072339 Increase 124 141 contact urticaria Negative_phenotype 159 167 potatoes Plant

10072339 Increase 159 167 potatoes Plant 225 235 dermatitis Negative_phenotype

10072339_6 The investigations showed a positive prick test, a positive patch test, and positive specific serum IgE to raw potato.

10072339 111 117 potato Plant

10072339_7 Potato avoidance led not only to the resolution of the immediate symptoms, but also of the facial dermatitis, suggesting she had dermatitis due to this vegetable.

10072339 0 6 Potato Plant

10072339 91 108 facial dermatitis Negative_phenotype

10072339 129 139 dermatitis Negative_phenotype

10072339 Increase 0 6 Potato Plant 91 108 facial dermatitis Negative_phenotype

10072339 Increase 0 6 Potato Plant 129 139 dermatitis Negative_phenotype

10072339_8 CONCLUSIONS: Potato may induce contact dermatitis with positive immediate and delayed hypersensitivity tests.

10072339 13 19 Potato Plant

10072339 31 49 contact dermatitis Negative_phenotype

10072339 Increase 13 19 Potato Plant 31 49 contact dermatitis Negative_phenotype

10094584_1 Anti-obesity action of oolong tea.

10094584 0 12 Anti-obesity Positive_phenotype

10094584 30 33 tea Plant

10094584_2 OBJECTIVE: Oolong tea is traditionally reported to have anti-obesity and hypolipidaemic effects.

10094584 18 21 tea Plant

10094584 56 68 anti-obesity Positive_phenotype

10094584 73 87 hypolipidaemic Negative_phenotype

10094584 Increase 18 21 tea Plant 56 68 anti-obesity Positive_phenotype

10094584 Decrease 18 21 tea Plant 73 87 hypolipidaemic Negative_phenotype

10094584_3 The present study was performed to clarify whether oolong tea prevented obesity induced in mice by the oral administration of a high-fat diet for 10 weeks.

10094584 58 61 tea Plant

10094584 72 79 obesity Negative_phenotype

10094584_4 DESIGN: High-fat diet-induced obese mice were treated with oolong tea for 10 weeks.

10094584 30 35 obese Negative_phenotype

10094584 66 69 tea Plant

10094584_5 The effects of various active fractions isolated from oolong tea on noradrenaline-induced lipolysis were examined with isolated fat cells and a cell-free system consisting of lipid droplets and hormone-sensitive lipase (HSL).

10094584 61 64 tea Plant

10094584_6 RESULTS: The mean food consumption was not significantly different between high-fat diet-treated mice and high-fat plus oolong tea diet-treated mice.

10094584 127 130 tea Plant

10094584_7 Oolong tea prevented the obesity and fatty liver induced by a high-fat diet.

10094584 7 10 tea Plant

10094584 25 32 obesity Negative_phenotype

10094584 37 48 fatty liver Negative_phenotype

10094584 Decrease 7 10 tea Plant 25 32 obesity Negative_phenotype

10094584 Decrease 7 10 tea Plant 37 48 fatty liver Negative_phenotype

10094584_8 A water extract of oolong tea enhanced noradrenaline-induced lipolysis, and the active substance was identified as caffeine.

10094584 26 29 tea Plant

10094584_9 Caffeine enhanced noradrenaline-induced lipolysis in fat cells without a concomitant increase in HSL activity and also accelerated the hormone-induced lipolysis in a cell-free system consisting of lipid droplets and HSL, but not in the cell-free system with sonicated lipid droplets and HSL.

10094584_10 Oolong tea extract inhibited pancreatic lipase activity.

10094584 7 10 tea Plant

10094584_11 CONCLUSION: It was demonstrated that the anti-obesity effects of oolong tea in high-fat diet-treated mice might be due partly to the enhancing effect of caffeine isolated from oolong tea on noradrenaline-induced lipolysis in adipose tissue, and to the inhibitory action of some other substance in oolong tea on pancreatic lipase activity.

10094584 41 53 anti-obesity Positive_phenotype