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PubMedQA-fine-tuned-llama-3-1-8B-labels

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[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nInternal derangement of the temporomandibular joint: is there still a place for ultrasound?\n\nContext:\n-OBJECTIVE: The aim of this study was to assess the diagnostic value of articular sounds, standardized clinical examination, and standardized articular ultrasound in the detection of internal derangements of the temporomandibular joint.\n-STUDY DESIGN: Forty patients and 20 asymptomatic volunteers underwent a standardized interview, physical examination, and static and dynamic articular ultrasound. Sensitivity, specificity, and predictive values were calculated using magnetic resonance as the reference test.\n-RESULTS: A total of 120 temporomandibular joints were examined. Based on our findings, the presence of articular sounds and physical signs are often insufficient to detect disk displacement. Imaging by static and dynamic high-resolution ultrasound demonstrates considerably lower sensitivity when compared with magnetic resonance. Some of the technical difficulties resulted from a limited access because of the presence of surrounding bone structures.'}]

no

The study found that imaging by static and dynamic high-resolution ultrasound demonstrates considerably lower sensitivity when compared with magnetic resonance in detecting internal derangements of the temporomandibular joint.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nLaparoscopic myomectomy: do size, number, and location of the myomas form limiting factors for laparoscopic myomectomy?\n\nContext:\n-STUDY OBJECTIVE: To assess whether it is possible for an experienced laparoscopic surgeon to perform efficient laparoscopic myomectomy regardless of the size, number, and location of the myomas.\n-DESIGN: Prospective observational study (Canadian Task Force classification II-1).\n-SETTING: Tertiary endoscopy center.\n-PATIENTS: A total of 505 healthy nonpregnant women with symptomatic myomas underwent laparoscopic myomectomy at our center. No exclusion criteria were based on the size, number, or location of myomas.\n-INTERVENTIONS: Laparoscopic myomectomy and modifications of the technique: enucleation of the myoma by morcellation while it is still attached to the uterus with and without earlier devascularization.\n-MEASUREMENTS AND MAIN RESULTS: In all, 912 myomas were removed in these 505 patients laparoscopically. The mean number of myomas removed was 1.85 +/- 5.706 (95% CI 1.72-1.98). In all, 184 (36.4%) patients had multiple myomectomy. The mean size of the myomas removed was 5.86 +/- 3.300 cm in largest diameter (95% CI 5.56-6.16 cm). The mean weight of the myomas removed was 227.74 +/- 325.801 g (95% CI 198.03-257.45 g) and median was 100 g. The median operating time was 60 minutes (range 30-270 minutes). The median blood loss was 90 mL (range 40-2000 mL). Three comparisons were performed on the basis of size of the myomas (<10 cm and>or=10 cm in largest diameter), number of myomas removed (<or=4 and>or=5 myomas), and the technique (enucleation of the myomas by morcellation while the myoma is still attached to the uterus and the conventional technique). In all these comparisons, although the mean blood loss, duration of surgery, and hospital stay were greater in the groups in which larger myomas or more myomas were removed or the modified technique was performed as compared with their corresponding study group, the weight and size of removed myomas were also proportionately larger in these groups. Two patients were given the diagnosis of leiomyosarcoma in their histopathology and 1 patient developed a diaphragmatic parasitic myoma followed by a leiomyoma of the sigmoid colon. Six patients underwent laparoscopic hysterectomy 4 to 6 years after the surgery for recurrent myomas. One conversion to laparotomy occurred and 1 patient underwent open subtotal hysterectomy for dilutional coagulopathy.'}]

no

The size, number, and location of the myomas do not form limiting factors for laparoscopic myomectomy, as an experienced laparoscopic surgeon can perform efficient laparoscopic myomectomy regardless of these factors.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs intensive chemotherapy safe for rural cancer patients?\n\nContext:\n-BACKGROUND: To provide equality of cancer care to rural patients, Townsville Cancer Centre administers intensive chemotherapy regimens to rural patients with node-positive breast and metastatic colorectal cancers at the same doses as urban patients. Side-effects were usually managed by rural general practitioners locally.AIM: The aim is to determine the safety of this practice by comparing the profile of serious adverse events and dose intensities between urban and rural patients at the Townsville Cancer Centre.\n-METHOD: A retrospective audit was conducted in patients with metastatic colorectal and node-positive breast cancers during a 24-month period. Fisher\'s exact test was used for analysis. Rurality was determined as per rural, remote and metropolitan classification.\n-RESULTS: Of the 121 patients included, 70 and 51 patients had breast and colon cancers respectively. The urban versus rural patient split among all patients, breast and colorectal cancer subgroups was 68 versus 53, 43 versus 27 and 25 versus 26 respectively. A total of 421 cycles was given with dose intensity of>95% for breast cancer in both groups (P>0.05). Rate of febrile neutropenia was 9.3% versus 7.4% (P = 0.56). For XELOX, rate of diarrhoea was 20% versus 19% (P = 0.66) and rate of vomiting was 20% versus 11% (P = 0.11). Only two patients were transferred to Townsville for admission. No toxic death occurred in either group.'}]

yes

Intensive chemotherapy is safe for rural cancer patients, as evidenced by the similar rate of serious adverse events and dose intensities between urban and rural patients.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes sex affect the outcome of laparoscopic cholecystectomy?\n\nContext:\n-INTRODUCTION: The aim of our study was to determine the effect of sex on the outcome of laparoscopic cholecystectomy in terms of operative time, conversion to open cholecystectomy, postoperative complications and mean hospital stay.\n-METHODS: In this retrospective observational study, we analyzed the medical records of 2061 patients who underwent laparoscopic cholecystectomy in the surgical department of Khyber Teaching Hospital (Peshawar, Pakistan) between March 2008 and January 2010. χ(2) test and t-test were respectively used to analyze categorical and numerical variables. P\u2009≤\u20090.05 was considered significant.\n-RESULTS: The study included 1772 female and 289 male patients. The mean age for male patients was 44.07\u2009±\u200911.91 years compared to 41.29\u2009±\u200912.18 years for female patients (P\u2009=\u20090.706). Laparoscopic cholecystectomy was successfully completed in 1996 patients. The conversion rate was higher in men (P\u2009<\u20090.001), and the mean operating time was longer in men (P\u2009<\u20090.001). Bile duct injuries occurred more frequently in men (P\u2009<\u20090.001). Gallbladder perforation and gallstone spillage also occurred more commonly in men (P\u2009=\u20090.001); similarly severe inflammation was reported more in male patients (P\u2009=\u20090001). There were no statistically significant differences in mean hospital stay, wound infection and port-site herniation between men and women. Multivariate regression analysis showed that the male sex is an independent risk factor for conversion to open cholecystectomy (odds ratio\u2009=\u20092.65, 95% confidence interval: 1.03-6.94, P\u2009=\u20090.041) and biliary injuries (odds ratio\u2009=\u20090.95, 95% confidence interval: 0.91-0.99, P-value\u2009=\u20090.036).'}]

yes

The study found that sex affects the outcome of laparoscopic cholecystectomy, with male patients having a higher conversion rate, longer operating time, and more frequent bile duct injuries, gallbladder perforation, gallstone spillage, and severe inflammation compared to female patients.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs atropine needed with ketamine sedation?\n\nContext:\n-OBJECTIVE: To compare atropine with placebo as an adjunct to ketamine sedation in children undergoing minor painful procedures. Outcome measures included hypersalivation, side effect profile, parental/patient satisfaction, and procedural success rate.\n-METHODS: Children aged between 1 and 16 years of age requiring ketamine procedural sedation in a tertiary emergency department were randomised to receive 0.01 mg/kg of atropine or placebo. All received 4 mg/kg of intramuscular ketamine. Tolerance and sedation scores were recorded throughout the procedure. Side effects were recorded from the start of sedation until discharge. Parental and patient satisfaction scores were obtained at discharge and three to five days after the procedure, with the opportunity to report side effects encountered at home.\n-RESULTS: A total of 83 patients aged 13 months to 14.5 years (median age 3.4 years) were enrolled over a 16 month period. Hypersalivation occurred in 11.4% of patients given atropine compared with 30.8% given placebo (odds ratio (OR) 0.29, 95% confidence interval (CI) 0.09 to 0.91). A transient rash was observed in 22.7% of the atropine group compared with 5.1% of the placebo group (OR 5.44, 95% CI 1.11 to 26.6). Vomiting during recovery occurred in 9.1% of atropine patients compared with 25.6% of placebo patients (OR 0.29, 95% CI 0.09 to 1.02). There was a trend towards better tolerance in the placebo group. No patient experienced serious side effects.'}]

no

Atropine is not strictly needed with ketamine sedation, as the study found that hypersalivation occurred in 30.8% of patients given placebo compared to 11.4% given atropine, and there was a trend towards better tolerance in the placebo group.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes implant coating with antibacterial-loaded hydrogel reduce bacterial colonization and biofilm formation in vitro?\n\nContext:\n-BACKGROUND: Implant-related infections represent one of the most severe complications in orthopaedics. A fast-resorbable, antibacterial-loaded hydrogel may reduce or prevent bacterial colonization and biofilm formation of implanted biomaterials.QUESTIONS/\n-PURPOSES: We asked: (1) Is a fast-resorbable hydrogel able to deliver antibacterial compounds in vitro? (2) Can a hydrogel (alone or antibacterial-loaded) coating on implants reduce bacterial colonization? And (3) is intraoperative coating feasible and resistant to press-fit implant insertion?\n-METHODS: We tested the ability of Disposable Antibacterial Coating (DAC) hydrogel (Novagenit Srl, Mezzolombardo, Italy) to deliver antibacterial agents using spectrophotometry and a microbiologic assay. Antibacterial and antibiofilm activity were determined by broth microdilution and a crystal violet assay, respectively. Coating resistance to press-fit insertion was tested in rabbit tibias and human femurs.\n-RESULTS: Complete release of all tested antibacterial compounds was observed in less than 96 hours. Bactericidal and antibiofilm effect of DAC hydrogel in combination with various antibacterials was shown in vitro. Approximately 80% of the hydrogel coating was retrieved on the implant after press-fit insertion.'}]

yes

Implant coating with antibacterial-loaded hydrogel reduces bacterial colonization and biofilm formation in vitro, as shown by the bactericidal and antibiofilm effect of the DAC hydrogel in combination with various antibacterials.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDo family physicians know the costs of medical care?\n\nContext:\n-OBJECTIVE: To determine the cost of 46 commonly used investigations and therapies and to assess British Columbia family doctors\' awareness of these costs.\n-DESIGN: Mailed survey asking about costs of 23 investigations and 23 therapies relevant to family practice. A random sample of 600 doctors was asked to report their awareness of costs and to estimate costs of the 46 items.\n-SETTING: British Columbia.\n-PARTICIPANTS: Six hundred family physicians.\n-MAIN OUTCOME MEASURES: Estimates within 25% of actual cost were considered correct. Associations between cost awareness and respondents\'characteristics (eg, sex, practice location) were sought. Degree of error in estimates was also assessed.\n-RESULTS: Overall, 283 (47.2%) surveys were returned and 259 analyzed. Few respondents estimated costs within 25% of true cost, and estimates were highly variable. Physicians underestimated costs of expensive drugs and laboratory investigations and overestimated costs of inexpensive drugs. Cost awareness did not correlate with sex, practice location, College certification, faculty appointment, or years in practice.'}]

no

Few respondents estimated costs within 25% of true cost, and estimates were highly variable. Physicians underestimated costs of expensive drugs and laboratory investigations and overestimated costs of inexpensive drugs.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCombining process indicators to evaluate quality of care for surgical patients with colorectal cancer: are scores consistent with short-term outcome?\n\nContext:\n-OBJECTIVE: To determine if composite measures based on process indicators are consistent with short-term outcome indicators in surgical colorectal cancer care.\n-DESIGN: Longitudinal analysis of consistency between composite measures based on process indicators and outcome indicators for 85 Dutch hospitals.\n-SETTING: The Dutch Surgical Colorectal Audit database, the Netherlands.\n-PARTICIPANTS: 4732 elective patients with colon carcinoma and 2239 with rectum carcinoma treated in 85 hospitals were included in the analyses.\n-MAIN OUTCOME MEASURES: All available process indicators were aggregated into five different composite measures. The association of the different composite measures with risk-adjusted postoperative mortality and morbidity was analysed at the patient and hospital level.\n-RESULTS: At the patient level, only one of the composite measures was negatively associated with morbidity for rectum carcinoma. At the hospital level, a strong negative association was found between composite measures and hospital mortality and morbidity rates for rectum carcinoma (p<0.05), and hospital morbidity rates for colon carcinoma.'}]

yes

Combining process indicators to evaluate quality of care for surgical patients with colorectal cancer shows that only one composite measure was negatively associated with morbidity for rectum carcinoma at the patient level, but at the hospital level, a strong negative association was found between composite measures and hospital mortality and morbidity rates for rectum carcinoma and hospital morbidity rates for colon carcinoma.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis?\n\nContext:\n-BACKGROUND AND AIMS: In familial adenomatous polyposis (FAP), correlations between site of mutation in the adenomatous polyposis coli (APC) gene and severity of colonic polyposis or extracolonic manifestations are well known. While mutation analysis is important for predictive diagnosis in persons at risk, its relevance for clinical management of individual patients is open to question.\n-METHODS: We examined 680 unrelated FAP families for germline mutations in the APC gene. Clinical information was obtained from 1256 patients.\n-RESULTS: APC mutations were detected in 48% (327/680) of families. Age at diagnosis of FAP based on bowel symptoms and age at diagnosis of colorectal cancer in untreated patients were used as indicators of the severity of the natural course of the disease. A germline mutation was detected in 230 of 404 patients who were diagnosed after onset of bowel symptoms (rectal bleeding, abdominal pain, diarrhoea). When these patients were grouped according to the different sites of mutations, mean values for age at onset of disease differed significantly: patients carrying APC mutations at codon 1309 showed a disease onset 10 years earlier (mean age 20 years) compared with patients with mutations between codons 168 and 1580 (except codon 1309) (mean age 30 years), whereas patients with mutations at the 5\' end of codon 168 or the 3\' end of codon 1580 were diagnosed at a mean age of 52 years. Within each group of patients however large phenotypic variation was observed, even among patients with identical germline mutations. A higher incidence of desmoids was found in patients with mutations between codons 1445 and 1580 compared with mutations at other sites, while no correlation between site of mutation and presence of duodenal adenomas was observed.'}]

yes

APC mutation analysis can contribute to therapeutic decisions in familial adenomatous polyposis by providing information on the severity of the natural course of the disease, such as age at diagnosis of FAP and colorectal cancer, and the presence of extracolonic manifestations like desmoids.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDo emergency medical services professionals think they should participate in disease prevention?\n\nContext:\n-OBJECTIVE: The primary objective of the study was to determine emergency medical services (EMS) professionals\' opinions regarding participation in disease and injury prevention programs. A secondary objective was to determine the proportion of EMS professionals who had participated in disease prevention programs.\n-METHODS: As part of the National Registry of Emergency Medical Technicians\' biennial reregistration process, EMS professionals reregistering in 2006 were asked to complete an optional survey regarding their opinions on and participation in disease and injury prevention. Demographic characteristics were also collected. Data were analyzed using descriptive statistics and 99% confidence intervals (CIs). The chi-square test was used to compare differences by responder demographics (alpha = 0.01). A 10% difference between groups was determined to be clinically significant.\n-RESULTS: The survey was completed by 27,233 EMS professionals. Of these responders, 82.7% (99% CI: 82.1-83.3) felt that EMS professionals should participate in disease prevention, with those working 20 to 29 hours per week being the least likely to think they should participate (67.4%, p<0.001). About a third, 33.8% (99% CI: 33.1-34.6), of the respondents reported having provided prevention services, with those having a graduate degree (43.5%, p<0.001), those working in EMS for more than 21 years (44%, p<0.001), those working for the military (57%, p<0.001), those working 60 to 69 hours per week (41%, p<0.001), and those responding to zero emergency calls in a typical week (43%, p<0.001) being the most likely to report having provided prevention services. About half, 51.1% (99% CI: 50.4-51.9), of the respondents agreed that prevention services should be provided during emergency calls, and 7.7% (99% CI: 7.3-8.1) of the respondents reported providing prevention services during emergency calls. No demographic differences existed. Those who had participated in prevention programs were more likely to respond that EMS professionals should participate in prevention (92% vs. 82%, p<0.001). Further, those who had provided prevention services during emergency calls were more likely to think EMS professionals should provide prevention services during emergency calls (81% vs. 51%, p<0.001).'}]

yes

82.7% of EMS professionals felt that EMS professionals should participate in disease prevention.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs the ability to perform transurethral resection of the prostate influenced by the surgeon\'s previous experience?\n\nContext:\n-PURPOSE: To evaluate the influence of the urologist\'s experience on the surgical results and complications of transurethral resection of the prostate (TURP).\n-PATIENTS AND METHODS: Sixty-seven patients undergoing transurethral resection of the prostate without the use of a video camera were randomly allocated into three groups according to the urologist\'s experience: a urologist having done 25 transurethral resections of the prostate (Group I - 24 patients); a urologist having done 50 transurethral resections of the prostate (Group II - 24 patients); a senior urologist with vast transurethral resection of the prostate experience (Group III - 19 patients). The following were recorded: the weight of resected tissue, the duration of the resection procedure, the volume of irrigation used, the amount of irrigation absorbed and the hemoglobin and sodium levels in the serum during the procedure.\n-RESULTS: There were no differences between the groups in the amount of irrigation fluid used per operation, the amount of irrigation fluid absorbed or hematocrit and hemoglobin variation during the procedure. The weight of resected tissue per minute was approximately four times higher in group III than in groups I and II. The mean absorbed irrigation fluid was similar between the groups, with no statistical difference between them (p=0.24). Four patients (6%) presented with TUR syndrome, without a significant difference between the groups.'}]

yes

The ability to perform transurethral resection of the prostate is influenced by the surgeon's previous experience, as the weight of resected tissue per minute was approximately four times higher in the group with the most experienced surgeon compared to the other groups.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs there a differential in the dental health of new recruits to the British Armed Forces?\n\nContext:\n-BACKGROUND AND AIM: Figures from the British Defence Dental Services reveal that serving personnel in the British Army have a persistently lower level of dental fitness than those in the Royal Navy or the Royal Air Force. No research had been undertaken to ascertain if this reflects the oral health of recruits joining each Service. This study aimed to pilot a process for collecting dental and sociodemographic data from new recruits to each Service and examine the null hypothesis that no differences in dental health existed.\n-METHOD: Diagnostic criteria were developed, a sample size calculated and data collected at the initial training establishments of each Service.\n-RESULTS: Data for 432 participants were entered into the analysis. Recruits in the Army sample had a significantly greater prevalence of dental decay and greater treatment resource need than either of the other two Services. Army recruits had a mean number of 2.59 (2.08, 3.09) decayed teeth per recruit, compared to 1.93 (1.49, 2.39 p<0.01) in Royal Navy recruits and 1.26 (0.98, 1.53 p<0.001) in Royal Air Force recruits. Among Army recruits 62.7% were from the two most deprived quintiles of the Index of Multiple Deprivation compared to 42.5% of Royal Naval recruits and 36.6% of Royal Air Force recruits.'}]

yes

Yes, there is a differential in the dental health of new recruits to the British Armed Forces, with Army recruits having a significantly greater prevalence of dental decay and greater treatment resource need compared to Royal Navy and Royal Air Force recruits.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs laparoscopic reoperation for failed antireflux surgery feasible?\n\nContext:\n-HYPOTHESIS: Laparoscopic techniques can be used to treat patients whose antireflux surgery has failed.\n-DESIGN: Case series.\n-SETTING: Two academic medical centers.\n-PATIENTS: Forty-six consecutive patients, of whom 21 were male and 25 were female (mean age, 55.6 years; range, 15-80 years). Previous antireflux procedures were laparoscopic (21 patients), laparotomy (21 patients), thoracotomy (3 patients), and thoracoscopy (1 patient).\n-MAIN OUTCOME MEASURES: The cause of failure, operative and postoperative morbidity, and the level of follow-up satisfaction were determined for all patients.\n-RESULTS: The causes of failure were hiatal herniation (31 patients [67%]), fundoplication breakdown (20 patients [43%]), fundoplication slippage (9 patients [20%]), tight fundoplication (5 patients [11%]), misdiagnosed achalasia (2 patients [4%]), and displaced Angelchik prosthesis (2 patients [4%]). Twenty-two patients (48%) had more than 1 cause. Laparoscopic reoperative procedures were Nissen fundoplication (n = 22), Toupet fundoplication (n = 13), paraesophageal hernia repair (n = 4), Dor procedure (n = 2), Angelchik prosthesis removal (n = 2), Heller myotomy (n = 2), and the takedown of a wrap (n = 1). In addition, 18 patients required crural repair and 13 required paraesophageal hernia repair. The mean +/- SEM duration of surgery was 3.5+/-1.1 hours. Operative complications were fundus tear (n = 8), significant bleeding (n = 4), bougie perforation (n = 1), small bowel enterotomy (n = 1), and tension pneumothorax (n = 1). The conversion rate (from laparoscopic to an open procedure) was 20% overall (9 patients) but 0% in the last 10 patients. Mortality was 0%. The mean +/- SEM hospital stay was 2.3+/-0.9 days for operations completed laparoscopically. Follow-up was possible in 35 patients (76%) at 17.2+/-11.8 months. The well-being score (1 best; 10, worst) was 8.6+/-2.1 before and 2.9+/-2.4 after surgery (P<.001). Thirty-one (89%) of 35 patients were satisfied with their decision to have reoperation.'}]

yes

Laparoscopic reoperation for failed antireflux surgery is feasible, with a successful outcome in 89% of patients, and a low mortality rate of 0%.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes exercise during pregnancy prevent postnatal depression?\n\nContext:\n-OBJECTIVE: To study whether exercise during pregnancy reduces the risk of postnatal depression.\n-DESIGN: Randomized controlled trial.\n-SETTING: Trondheim and Stavanger University Hospitals, Norway.\n-POPULATION AND SAMPLE: Eight hundred and fifty-five pregnant women were randomized to intervention or control groups.\n-METHODS: The intervention was a 12 week exercise program, including aerobic and strengthening exercises, conducted between week 20 and 36 of pregnancy. One weekly group session was led by physiotherapists, and home exercises were encouraged twice a week. Control women received regular antenatal care.\n-MAIN OUTCOME MEASURES: Edinburgh Postnatal Depression Scale (EPDS) completed three months after birth. Scores of 10 or more and 13 or more suggested probable minor and major depression, respectively.\n-RESULTS: Fourteen of 379 (3.7%) women in the intervention group and 17 of 340 (5.0%) in the control group had an EPDS score of ≥10 (p=0.46), and four of 379 (1.2%) women in the intervention group and eight of 340 (2.4%) in the control group had an EPDS score of ≥13 (p=0.25). Among women who did not exercise prior to pregnancy, two of 100 (2.0%) women in the intervention group and nine of 95 (9.5%) in the control group had an EPDS score of ≥10 (p=0.03).'}]

no

Exercise during pregnancy does not significantly reduce the risk of postnatal depression, as evidenced by the similar EPDS scores in the intervention and control groups.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs endometrial polyp formation associated with increased expression of vascular endothelial growth factor and transforming growth factor-beta1?\n\nContext:\n-OBJECTIVE: Endometrial polyp is a common cause of abnormal uterine bleeding, but the etiology and pathogenesis remain unclear. Vascular endothelial growth factor (VEGF) is angiogenic, related to thick walled vessels and transforming growth factor-beta1 (TGF-β1) is related to fibrotic tissue, which are characteristics of endometrial polyps. The primary objective of this study was to find out if endometrial polyp formation is associated with increased expression of VEGF or TGF-β1, or both. A secondary objective is to determine if the changes are related to steroid receptor expression.\n-STUDY DESIGN: This prospective study compared VEGF and TGF-β1 expression of endometrial polyps and adjacent endometrial tissue in 70 premenopausal women. The comparison of results was separately made for endometrium specimens obtained in the proliferative and secretory phases. The results were correlated with the steroid receptors (estrogen receptor and progesterone receptor) expression.\n-RESULTS: The score of VEGF in glandular cells of endometrial polyps was significantly higher than the score in adjacent endometrium, both in the proliferative phase (P<0.001) and the secretory phase (P=0.03); the score of VEGF in stromal cells of endometrial polyps was significantly higher than the score in adjacent endometrium only in proliferative phase (P=0.006). The score of TGF-β1 in glandular cells of endometrial polyps was significantly higher than the score in adjacent endometrium in proliferative phase (P=0.02); whereas the score of TGF-β1 in stromal cells of endometrial polyps was significantly higher than the score in adjacent endometrium, both in the proliferative phase (P=0.006) and the secretory phase (P=0.008). There was a significant correlation between the expression of steroid receptors and VEGF and TGF-β1 (Spearman\'s correlation P<0.001 and P<0.05, respectively).'}]

yes

Endometrial polyp formation is associated with increased expression of vascular endothelial growth factor (VEGF) and transforming growth factor-beta1 (TGF-β1) in both glandular and stromal cells, as evidenced by significantly higher scores in endometrial polyps compared to adjacent endometrium in various phases of the menstrual cycle.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs human cytomegalovirus infection associated with hypertension?\n\nContext:\n-PURPOSE: Recent studies have implicated the human cytomegalovirus (HCMV) as a possible pathogen for causing hypertension. We aimed to study the association between HCMV infection and hypertension in the United States National Health and Nutrition Examination Survey (NHANES).\n-METHODS: We analyzed data on 2979 men and 3324 women in the NHANES 1999-2002. We included participants aged 16-49 years who had valid data on HCMV infection and hypertension.\n-RESULTS: Of the participants, 54.7% had serologic evidence of HCMV infection and 17.5% had hypertension. There were ethnic differences in the prevalence of HCMV infection (P<0.001) and hypertension (P<0.001). The prevalence of both increased with age (P<0.001). Before adjustment, HCMV seropositivity was significantly associated with hypertension in women (OR=1.63, 95% CI=1.25-2.13, P=0.001) but not in men. After adjustment for race/ethnicity, the association between HCMV seropositivity and hypertension in women remained significant (OR=1.55, 95% CI=1.20-2.02, P=0.002). Further adjustment for body mass index, diabetes status and hypercholesterolemia attenuated the association (OR=1.44, 95% CI=1.10-1.90, P=0.010). However, after adjusting for age, the association was no longer significant (OR=1.24, 95% CI=0.91-1.67, P=0.162).'}]

yes

Human cytomegalovirus infection is associated with hypertension in women, but the association is attenuated after adjusting for various factors, and becomes non-significant after adjusting for age.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs it possible to stop treatment with nucleos(t)ide analogs in patients with e-antigen negative chronic hepatitis B?\n\nContext:\n-BACKGROUND: Treatment of HBeAg-negative chronic hepatitis B (CHB) with nucleos(t)ide analogues (NA) is usually indefinite, since the loss of HBsAg, as a criterion for its discontinuation, is a rare event. Recent evidence suggests that discontinuing NA therapy may be feasible in selected patients.\n-OBJECTIVES: To analyze the rate of virological relapse in patients with HBeAg-negative CHB who discontinued treatment with NAs.\n-METHODS: We performed a single-center observational study that included 140 patients with HBsAg-negative CHB. Twenty-two patients, who received only NAs, discontinued treatment for different reasons and were subsequently monitored. All had normal ALT and AST, undetectable DNA and absence of cirrhosis or significant comorbidities before stopping treatment.\n-RESULTS: Twelve patients showed virologic relapse (54.54%). The mean interval between discontinuation and relapse was 6.38 months (± 1.9) (75% relapsed during the first 12 months after discontinuation). Five received adefovir, 1 lamivudine and adefovir, 1 tenofovir and 5 lamivudine alone. The mean treatment duration in this group was 38.5 months (± 4.5). The sustained response group had a higher mean age and longer treatment duration than patients with virologic relapse but these differences were not statistically significant.'}]

yes

Recent evidence suggests that discontinuing NA therapy may be feasible in selected patients, and 12 out of 22 patients who discontinued treatment with NAs showed virologic relapse, with a mean interval between discontinuation and relapse of 6.38 months.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes radiotherapy around the time of pregnancy for Hodgkin\'s disease modify the risk of breast cancer?\n\nContext:\n-PURPOSE: To determine whether the risk of secondary breast cancer after radiotherapy (RT) for Hodgkin\'s disease is greater among women who underwent RT around time of pregnancy.\n-METHODS AND MATERIALS: The records of 382 women treated with RT for Hodgkin\'s disease were reviewed and divided into those who received RT around the time of pregnancy and those who were not pregnant. Comparisons of the overall incidence, actuarial rates, and latency to breast cancer between the two groups were made. Multivariate Cox regression modeling was performed to determine possible contributing factors.\n-RESULTS: Of the 382 women, 14 developed breast cancer (3.7%). The increase in the overall incidence (16.0% vs. 2.3%, p = 0.0001) and the actuarial rate of breast cancer among the women in the pregnant group (p = 0.011) was statistically significant. The women treated around the time of pregnancy had a 10- and 15-year actuarial rate of breast cancer of 6.7% and 32.6%, respectively. The 10-year and 15-year actuarial rate for the nonpregnant women was 0.4% and 1.7%, respectively. The median latency from RT to the diagnosis of breast cancer was 13.1 and 18.9 years for women in the pregnant and nonpregnant groups, respectively. In the multivariate analysis, pregnancy around the time of RT was the only variable associated with an increased risk of breast cancer. The risk was dependent on the length of time from pregnancy to RT, with women receiving RT during pregnancy and within 1 month of pregnancy having an increased risk of breast cancer compared with nonpregnant women and women irradiated later than 1 month after pregnancy (hazard ratio, 22.49; 95% confidence interval, 5.56-90.88; p<0.001).'}]

yes

Radiotherapy around the time of pregnancy for Hodgkin's disease modifies the risk of breast cancer, with an increased overall incidence and actuarial rate of breast cancer in the pregnant group compared to the nonpregnant group.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nShould displaced midshaft clavicular fractures be treated surgically?\n\nContext:\n-PURPOSE: This study was designed to compare clinical effectiveness of operative with nonoperative treatment for displaced midshaft clavicular fractures (DMCF).\n-METHODS: We systematically searched electronic databases (MEDILINE, EMBASE, CLINICAL, OVID, BIOSIS and Cochrane registry of controlled clinical trials) to identify randomized controlled trials (RCTs) in which operative treatment was compared with nonoperative treatment for DMCF from 1980 to 2012. The methodologic quality of trials was assessed. Data from chosen studies were pooled with using of fixed-effects and random-effects models with mean differences and risk ratios for continuous and dichotomous variables, respectively.\n-RESULTS: Four RCTs with a total of 321 patients were screened for the present study. Results showed that the operative treatment was superior to the nonoperative treatment regarding the rate of nonunion [95\xa0% confidence interval (CI) (0.05, 0.43), P\xa0=\xa00.0004], malunion [95\xa0% CI (0.06, 0.34), P\xa0<\xa00.00001] and overall complication [95\xa0% CI (0.43-0.76), P\xa0=\xa00.0001]. Subgroup analyses of complications revealed that significant differences were existed in the incidence of neurologic symptoms [95\xa0% CI (0.20, 0.74), P\xa0=\xa00.004] and dissatisfaction with appearance [95\xa0% CI (0.19, 0.65), P\xa0=\xa00.001]. Lack of consistent and standardized assessment data, insufficiency analysis that carried out showed improved functional outcomes (P\xa0<\xa00.05) in operative treatment.'}]

yes

The operative treatment was superior to the nonoperative treatment regarding the rate of nonunion, malunion, and overall complication, indicating that displaced midshaft clavicular fractures should be treated surgically.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs laparoscopic cholecystectomy safe and acceptable as a day case procedure?\n\nContext:\n-BACKGROUND: This study reviewed the results of performing day case laparoscopic cholecystectomy to assess the feasibility and safety of the procedure as a day case.\n-MATERIALS AND METHODS: This is a prospective study of 150 day case laparoscopic cholecystectomies performed between September 1999 and December 2004 under the care of the senior author. The results of a follow-up questionnaire to assess post-discharge clinical course and patient satisfaction were analyzed. All patients had commenced eating and drinking and were fully mobile before discharge home. The length of hospital stay was 4-8 hours.\n-RESULTS: The mean age of the patients was 43 years; 134 patients had an American Society of Anesthesiologists grade I, the remaining 16 patients were grade II. The mean operative time was 41 minutes. There were no conversions to open procedures. There was no bleeding, no visceral injury, and no mortality. There was one admission directly from the day surgical unit (admission rate of 0.6%), but no readmission following discharge. No patients were admitted due to postoperative nausea or pain. Ninety-nine (66%) of 150 patients responded to our questionnaire: 97% were satisfied about the information they had received. Patients rated their satisfaction with the procedure as follows: 75% excellent, 21% good, 3% satisfied, and 1 patient un-satisfied. Ninety-four percent of the patients would recommend the procedure as a day case.'}]

yes

The study found that laparoscopic cholecystectomy was safe and acceptable as a day case procedure, with a low admission rate of 0.6% and high patient satisfaction rate of 97%.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs etoricoxib effective in preventing heterotopic ossification after primary total hip arthroplasty?\n\nContext:\n-PURPOSE: Heterotopic ossification is a common complication after total hip arthroplasty. Non-steroidal anti-inflammatory drugs (NSAIDs) are known to prevent heterotopic ossifications effectively, however gastrointestinal complaints are reported frequently. In this study, we investigated whether etoricoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor that produces fewer gastrointestinal side effects, is an effective alternative for the prevention of heterotopic ossification.\n-METHODS: We investigated the effectiveness of oral etoricoxib 90 mg for seven days in a prospective two-stage study design for phase-2 clinical trials in a small sample of patients (n\u2009=\u200942). A cemented primary total hip arthroplasty was implanted for osteoarthritis. Six months after surgery, heterotopic ossification was determined on anteroposterior pelvic radiographs using the Brooker classification.\n-RESULTS: No heterotopic ossification was found in 62 % of the patients that took etoricoxib; 31 % of the patients had Brooker grade 1 and 7 % Brooker grade 2 ossification.'}]

yes

Etoricoxib is effective in preventing heterotopic ossification after primary total hip arthroplasty, as 62% of patients who took etoricoxib had no heterotopic ossification, and only 7% had Brooker grade 2 ossification.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nShould serum pancreatic lipase replace serum amylase as a biomarker of acute pancreatitis?\n\nContext:\n-BACKGROUND: Serum pancreatic lipase may improve the diagnosis of pancreatitis compared to serum amylase. Both enzymes have been measured simultaneously at our hospital allowing for a comparison of their diagnostic accuracy.\n-METHODS: Seventeen thousand five hundred and thirty-one measurements of either serum amylase and or serum pancreatic lipase were made on 10 931 patients treated at a metropolitan teaching hospital between January 2001 and May 2003. Of these, 8937 were initially treated in the Emergency Department. These results were collected in a database, which was linked by the patients\' medical record number to the radiology and medical records. Patients with either an elevated lipase value or a discharge diagnosis of acute pancreatitis had their radiological diagnosis reviewed along with their biochemistry and histology record. The diagnosis of acute pancreatitis was made if there was radiological evidence of peripancreatic inflammation.\n-RESULTS: One thousand eight hundred and twenty-five patients had either elevated serum amylase and or serum pancreatic lipase. The medical records coded for pancreatitis in a further 55 whose enzymes were not elevated. Three hundred and twenty of these had radiological evidence of acute pancreatitis. Receiver operator characteristic analysis of the initial sample from patients received in the Emergency Department showed improved diagnostic accuracy for serum pancreatic lipase (area under the curve (AUC) 0.948) compared with serum amylase (AUC, 0.906, P<0.05). A clinically useful cut-off point would be at the diagnostic threshold; 208 U/L (normal<190 U/L) for serum pancreatic lipase and 114 U/L (normal 27-100 U/L) for serum amylase where the sensitivity was 90.3 cf., 76.8% and the specificity was 93 cf., 92.6%. 18.8% of the acute pancreatitis patients did not have elevated serum amylase while only 2.9% did not have elevated serum pancreatic lipase on the first emergency department measurement.'}]

yes

Serum pancreatic lipase has improved diagnostic accuracy for acute pancreatitis compared to serum amylase, with a higher area under the curve (AUC) on receiver operator characteristic analysis, and should be considered as a replacement for serum amylase as a biomarker of acute pancreatitis.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nRectal cancer threatening or affecting the prostatic plane: is partial prostatectomy oncologically adequate?\n\nContext:\n-METHOD: A multicentre, retrospective study was conducted of patients with rectal cancer threatening or affecting the prostatic plane, but not the bladder, judged by magnetic resonance imaging (MRI). The use of preoperative chemoradiotherapy and the type of urologic resection were correlated with the status of the pathological circumferential resection margin (CRM) and local recurrence.\n-RESULTS: A consecutive series of 126 men with rectal cancer threatening (44) or affecting (82) the prostatic plane on preoperative staging and operated with local curative intent between 1998 and 2010 was analysed. In patients who did not have chemoradiotherapy but had a preoperative threatened anterior margin the CRM-positive rate was 25.0%. In patients who did not have preoperative chemoradiotherapy but did have an affected margin, the CRM-positive rate was 41.7%. When preoperative radiotherapy was given, the respective CRM infiltration rates were 7.1 and 20.7%. In patients having preoperative chemoradiotherapy followed by prostatic resection the rate of CRM positivity was 2.4%. Partial prostatectomy after preoperative chemoradiotherapy resulted in a free anterior CRM in all cases, but intra-operative urethral damage occurred in 36.4% of patients who underwent partial prostatectomy, resulting in a postoperative urinary fistula in 18.2% of patients.'}]

yes

Partial prostatectomy after preoperative chemoradiotherapy resulted in a free anterior CRM in all cases, but intra-operative urethral damage occurred in 36.4% of patients who underwent partial prostatectomy, resulting in a postoperative urinary fistula in 18.2% of patients.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes bone anchor fixation improve the outcome of percutaneous bladder neck suspension in female stress urinary incontinence?\n\nContext:\n-OBJECTIVE: To evaluate the outcome of a new modification of percutaneous needle suspension, using a bone anchor system for fixing the suture at the public bone, and to compare the results with those published previously.\n-PATIENTS AND METHODS: From March 1996, 37 patients with stress urinary incontinence (>2 years) were treated using a bone anchor system. On each side the suture was attached to the pubocervical fascia and the vaginal wall via a broad \'Z\'-stitch. A urodynamic investigation performed preoperatively in all patients confirmed stress incontinence and excluded detrusor instability. The outcome was assessed by either by a clinical follow-up investigation or using a standardized questionnaire, over a mean follow-up of 11 months (range 6-18).\n-RESULTS: In the 37 patients, the procedure was successful in 25 (68%), with 16 (43%) of the patients completely dry and nine (24%) significantly improved. Removal of the bone anchor and suture was necessary in two patients, because of unilateral bacterial infection in one and a bilateral soft tissue granuloma in the other. One bone anchor became dislocated in a third patient. In two cases where the treatment failed, new detrusor instability was documented urodynamically. Minor complications were prolonged wound pain in 10 (26%) and transient urinary retention or residual urine in 12 patients (32%).'}]

yes

The use of a bone anchor system for fixing the suture at the public bone in percutaneous bladder neck suspension improves the outcome in female stress urinary incontinence, with a success rate of 68% and 43% of patients completely dry or significantly improved.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAre intraoperative precursor events associated with postoperative major adverse events?\n\nContext:\n-OBJECTIVES: Precursor events are undesirable events that can lead to a subsequent adverse event and have been associated with postoperative mortality. The purpose of the present study was to determine whether precursor events are associated with a composite endpoint of major adverse cardiac events (MACE) (death, acute renal failure, stroke, infection) in a low- to medium-risk coronary artery bypass grafting, valve, and valve plus coronary artery bypass grafting population. These events might be targets for strategies aimed at quality improvement.\n-METHODS: The present study was a retrospective cohort design performed at the Queen Elizabeth Health Science Centre. Low- to medium-risk patients who had experienced postoperative MACE were matched 1:1 with patients who had not experienced postoperative MACE. The operative notes, for both groups, were scored by 5 surgeons to determine the frequency of 4 precursor events: bleeding, difficulty weaning from cardiopulmonary bypass, repair or regrafting, and incomplete revascularization or repair. A univariate comparison of ≥1 precursor events in the matched groups was performed.\n-RESULTS: A total of 311 MACE patients (98.4%) were matched. The primary outcome occurred more frequently in the MACE group than in the non-MACE group (33% vs 24%; P\xa0=\xa0.015). The incidence of the individual events of bleeding and difficulty weaning from cardiopulmonary bypass was significantly higher in the MACE group. Those patients with a precursor event in the absence of MACE also appeared to have a greater prevalence of other important postoperative outcomes.'}]

yes

The study found that precursor events, such as bleeding and difficulty weaning from cardiopulmonary bypass, were associated with a higher incidence of major adverse cardiac events (MACE) in a low- to medium-risk coronary artery bypass grafting, valve, and valve plus coronary artery bypass grafting population.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes a family meetings intervention prevent depression and anxiety in family caregivers of dementia patients?\n\nContext:\n-BACKGROUND: Family caregivers of dementia patients are at increased risk of developing depression or anxiety. A multi-component program designed to mobilize support of family networks demonstrated effectiveness in decreasing depressive symptoms in caregivers. However, the impact of an intervention consisting solely of family meetings on depression and anxiety has not yet been evaluated. This study examines the preventive effects of family meetings for primary caregivers of community-dwelling dementia patients.\n-METHODS: A randomized multicenter trial was conducted among 192 primary caregivers of community dwelling dementia patients. Caregivers did not meet the diagnostic criteria for depressive or anxiety disorder at baseline. Participants were randomized to the family meetings intervention (n\u200a=\u200a96) or usual care (n\u200a=\u200a96) condition. The intervention consisted of two individual sessions and four family meetings which occurred once every 2 to 3 months for a year. Outcome measures after 12 months were the incidence of a clinical depressive or anxiety disorder and change in depressive and anxiety symptoms (primary outcomes), caregiver burden and quality of life (secondary outcomes). Intention-to-treat as well as per protocol analyses were performed.\n-RESULTS: A substantial number of caregivers (72/192) developed a depressive or anxiety disorder within 12 months. The intervention was not superior to usual care either in reducing the risk of disorder onset (adjusted IRR 0.98; 95% CI 0.69 to 1.38) or in reducing depressive (randomization-by-time interaction coefficient\u200a=\u200a-1.40; 95% CI -3.91 to 1.10) or anxiety symptoms (randomization-by-time interaction coefficient\u200a=\u200a-0.55; 95% CI -1.59 to 0.49). The intervention did not reduce caregiver burden or their health related quality of life.'}]

no

The family meetings intervention did not prevent depression and anxiety in family caregivers of dementia patients, as the intervention was not superior to usual care in reducing the risk of disorder onset or depressive/anxiety symptoms.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nHIF1A as a major vascular endothelial growth factor regulator: do its polymorphisms have an association with age-related macular degeneration?\n\nContext:\n-BACKGROUND: To investigate the association between age-related macular degeneration (AMD) and the polymorphisms of HIF1A, a major vascular epithelial growth factor regulator under hypoxic conditions. The associations of AMD and polymorphisms of genes CFH, SKIV2L and MYRIP were also studied.\n-DESIGN: Prospective study.\n-PARTICIPANTS: Eighty-seven AMD patients and 80 healthy subjects admitted to the Department of Ophthalmology at Pamukkale University Hospital, Denizli, Turkey, were included: 45 (52%) had wet type AMD, and 42 (48%) had dry type AMD.\n-METHODS: Polymorphisms rs1061170 (CFH), rs429608 (SKIV2L), rs2679798 (MYRIP) and both rs11549465 and rs11549467 (HIF1A) were investigated in DNA isolated from peripheral blood samples of the cases and controls by dye-termination DNA sequencing.\n-MAIN OUTCOME MEASURES: Genotype distribution of rs1061170 (CFH), rs429608 (SKIV2L), rs2679798 (MYRIP) and both rs11549465 and rs11549467 (HIF1A) in AMD cases and healthy controls; association between genotypes and AMD subtypes.\n-RESULTS: Given the significant difference between the mean age of case and control groups (72.13\u2009±\u20095.77 vs. 62.80\u2009±\u20095.22, respectively) (P\u2009=\u2009.000), subsequent analyses were adjusted for age. We found that having at least one C allele for polymorphism rs1061170 increases AMD risk independent of age (OR\u2009=\u20092.42, 95% confidence interval [CI], 1.22-4.81). The ancestral T allele for polymorphism rs1061170 has a protective effect for AMD (OR\u2009=\u20090.53, 95% CI, 0.34-0.83). No statistically significant difference for distributions of other single nucleotide polymorphisms (SNPs) emerged between patients and healthy subjects.'}]

no

The study found that having at least one C allele for polymorphism rs1061170 increases AMD risk independent of age, but it does not specifically mention the association between HIF1A polymorphisms and age-related macular degeneration.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs combined therapy more effective than growth hormone or hyperbaric oxygen alone in the healing of left ischemic and non-ischemic colonic anastomoses?\n\nContext:\n-OBJECTIVE: Our aim was to investigate the effects of growth hormone (GH), hyperbaric oxygen and combined therapy on normal and ischemic colonic anastomoses in rats.\n-METHODS: Eighty male Wistar rats were divided into eight groups (n\u200a=\u200a10). In the first four groups, non-ischemic colonic anastomosis was performed, whereas in the remaining four groups, ischemic colonic anastomosis was performed. In groups 5, 6, 7, and 8, colonic ischemia was established by ligating 2 cm of the mesocolon on either side of the anastomosis. The control groups (1 and 5) received no treatment. Hyperbaric oxygen therapy was initiated immediately after surgery and continued for 4 days in groups 3 and 4. Groups 2 and 6 received recombinant human growth hormone, whereas groups 4 and 8 received GH and hyperbaric oxygen treatment. Relaparotomy was performed on postoperative day 4, and a perianastomotic colon segment 2 cm in length was excised for the detection of biochemical and mechanical parameters of anastomotic healing and histopathological evaluation.\n-RESULTS: Combined treatment with hyperbaric oxygen and GH increased the mean bursting pressure values in all of the groups, and a statistically significant increase was noted in the ischemic groups compared to the controls (p<0.05). This improvement was more evident in the ischemic and normal groups treated with combined therapy. In addition, a histopathological evaluation of anastomotic neovascularization and collagen deposition showed significant differences among the groups.'}]

yes

Combined treatment with hyperbaric oxygen and GH increased the mean bursting pressure values in all of the groups, and a statistically significant increase was noted in the ischemic groups compared to the controls.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes oxybutynin hydrochloride cause arrhythmia in children with bladder dysfunction?\n\nContext:\n-METHOD: This study represents a subset of a complete data set, considering only those children aged admitted to the Pediatric Surgery and Pediatric Nephrology Clinics during the period January 2011 to July 2012.\n-RESULT: In this study, we have determined that the QT interval changes significantly depending on the use of oxybutynin. The QT changes increased cardiac arrhythmia in children.'}]

yes

The use of oxybutynin hydrochloride causes significant changes in the QT interval, which increases the risk of cardiac arrhythmia in children.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDo "America\'s Best Hospitals" perform better for acute myocardial infarction?\n\nContext:\n-BACKGROUND: "America\'s Best Hospitals," an influential list published annually by U.S. News and World Report, assesses the quality of hospitals. It is not known whether patients admitted to hospitals ranked at the top in cardiology have lower short-term mortality from acute myocardial infarction than those admitted to other hospitals or whether differences in mortality are explained by differential use of recommended therapies.\n-METHODS: Using data from the Cooperative Cardiovascular Project on 149,177 elderly Medicare beneficiaries with acute myocardial infarction in 1994 or 1995, we examined the care and outcomes of patients admitted to three types of hospitals: those ranked high in cardiology (top-ranked hospitals); hospitals not in the top rank that had on-site facilities for cardiac catheterization, coronary angioplasty, and bypass surgery (similarly equipped hospitals); and the remaining hospitals (non-similarly equipped hospitals). We compared 30-day mortality; the rates of use of aspirin, beta-blockers, and reperfusion; and the relation of differences in rates of therapy to short-term mortality.\n-RESULTS: Admission to a top-ranked hospital was associated with lower adjusted 30-day mortality (odds ratio, 0.87; 95 percent confidence interval, 0.76 to 1.00; P=0.05 for top-ranked hospitals vs. the others). Among patients without contraindications to therapy, top-ranked hospitals had significantly higher rates of use of aspirin (96.2 percent, as compared with 88.6 percent for similarly equipped hospitals and 83.4 percent for non-similarly equipped hospitals; P<0.01) and beta-blockers (75.0 percent vs. 61.8 percent and 58.7 percent, P<0.01), but lower rates of reperfusion therapy (61.0 percent vs. 70.7 percent and 65.6 percent, P=0.03). The survival advantage associated with admission to top-ranked hospitals was less strong after we adjusted for factors including the use of aspirin and beta-blockers (odds ratio, 0.94; 95 percent confidence interval, 0.82 to 1.08; P=0.38).'}]

yes

Admission to a top-ranked hospital was associated with lower adjusted 30-day mortality, but the survival advantage was less strong after adjusting for factors including the use of aspirin and beta-blockers.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes preoperative anemia adversely affect colon and rectal surgery outcomes?\n\nContext:\n-BACKGROUND: Complications associated with blood transfusions have resulted in widespread acceptance of low hematocrit levels in surgical patients. However, preoperative anemia seems to be a risk factor for adverse postoperative outcomes in certain surgical patients. This study investigated the National Surgical Quality Improvement Program (NSQIP) database to determine if preoperative anemia in patients undergoing open and laparoscopic colectomies is an independent predictor for an adverse composite outcome (CO) consisting of myocardial infarction, stroke, progressive renal insufficiency or death within 30 days of operation, or for an increased hospital length of stay (LOS).\n-STUDY DESIGN: Hematocrit levels were categorized into 4 classes: severe, moderate, mild, and no anemia. From 2005 to 2008, the NSQIP database recorded 23,348 elective open and laparoscopic colectomies that met inclusion criteria. Analyses using multivariable models, controlling for potential confounders and stratifying on propensity score, were performed.\n-RESULTS: Compared with nonanemic patients, those with severe, moderate, and mild anemia were more likely to have the adverse CO with odds ratios of 1.83 (95% CI 1.05 to 3.19), 2.19 (95 % CI 1.63 to 2.94), and 1.49 (95% CI 1.20 to 1.86), respectively. Patients with a normal hematocrit had a reduced hospital LOS, compared with those with severe, moderate, and mild anemia (p<0.01). A history of cardiovascular disease did not significantly influence these findings.'}]

yes

Preoperative anemia is an independent predictor for an adverse composite outcome in patients undergoing open and laparoscopic colectomies, including myocardial infarction, stroke, progressive renal insufficiency or death within 30 days of operation, and an increased hospital length of stay.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan early second-look tympanoplasty reduce the rate of conversion to modified radical mastoidectomy?\n\nContext:\n-OBJECTIVES: The aims of the study were to report the rates of recurrent and residual cholesteatoma following primary CAT surgery and to report the rate of conversion to a modified radical mastoidectomy.\n-METHODS: This was a retrospective review of a single surgeon series between 2006 and 2012.\n-RESULTS: In total 132 second-look operations were undertaken, with a mean interval between primary surgery and second-look procedures of 6 months. The rate of cholesteatoma at second-look surgery was 19.7%, which was split into residual disease (10.6%) and recurrent disease (9.09%). New tympanic membrane defects with cholesteatoma were considered as recurrent disease. Residual disease was defined as cholesteatoma present behind an intact tympanic membrane. The majority of recurrent and residual disease was easily removed at second look (73.1%). Only four cases were converted to a modified radical mastoidectomy (3%) and three cases required a third-look procedure.'}]

yes

The study found that only four cases were converted to a modified radical mastoidectomy, which is a low rate of 3%, indicating that early second-look tympanoplasty can effectively reduce the rate of conversion to modified radical mastoidectomy.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs serum total bilirubin useful to differentiate cardioembolic stroke from other stroke subtypes?\n\nContext:\n-BACKGROUND: Previous studies have reported that the total bilirubin (TB) level is associated with coronary artery disease, heart failure and atrial fibrillation. These heart diseases can produce cardiogenic cerebral embolism and cause cardioembolic stroke. However, whether the serum TB could be a biomarker to differentiate cardioembolic stroke from other stroke subtypes is unclear.\n-METHODS: Our study consisted of 628 consecutive patients with ischaemic stroke. Various clinical and laboratory variables of the patients were analysed according to serum TB quartiles and stroke subtypes.\n-RESULTS: The higher TB quartile group was associated with atrial fibrillation, larger left atrium diameter, lower left ventricular fractional shortening and cardioembolic stroke (P<0.001, P = 0.001, P = 0.033, P<0.001, respectively). Furthermore, serum TB was a statistically significant independent predictor of cardioembolic stroke in a multivariable setting (Continuous, per unit increase OR = 1.091, 95%CI: 1.023-1.164, P = 0.008).'}]

yes

Serum total bilirubin is a statistically significant independent predictor of cardioembolic stroke, indicating its usefulness in differentiating cardioembolic stroke from other stroke subtypes.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDelayed imaging in routine CT examinations of the abdomen and pelvis: is it worth the additional cost of radiation and time?\n\nContext:\n-OBJECTIVE: The purpose of this study was to retrospectively assess the potential benefits of delayed phase imaging series in routine CT scans of the abdomen and pelvis.\n-MATERIALS AND METHODS: Routine contrast-enhanced abdominopelvic CT scans of 1000 consecutively examined patients (912 men, 88 women; average age, 60 years; range, 22-94 years) were retrospectively evaluated, and the added benefits of the delayed phase series through the abdomen were recorded for each examination. Examinations performed for indications requiring multiphasic imaging were excluded. Images were reviewed by two fellowship-trained abdominal radiologists, who were blinded to official CT reports. All examinations were performed between July 2008 and February 2010 at a single institution. Radiation doses for both the portal venous and delayed phases, when available, were analyzed to assess the effect of the delayed phase on overall radiation exposure.\n-RESULTS: Forty-two patients (4.2%) had findings that were further characterized or were observed only in the delayed phase. Most were incidental findings that could have been confirmed at noninvasive follow-up imaging, such as sonography or unenhanced CT or MRI. The most common findings were liver hemangioma (n = 12), adrenal adenoma (n = 12), and parapelvic renal cysts (n = 6). The most important finding was detection of a renal mass in one patient (0.1%). The mass was seen only on the delayed phase images but was difficult to appreciate in the portal venous phase. In the other 958 patients (95.8%), delayed imaging was of no benefit. In addition, use of the delayed phase resulted in a mean 59.5% increase in effective radiation dose.'}]

maybe

Delayed imaging in routine CT examinations of the abdomen and pelvis revealed beneficial findings in 4.2% of patients, including incidental findings that could have been confirmed at noninvasive follow-up imaging, but resulted in a mean 59.5% increase in effective radiation dose.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nSuturing of the nasal septum after septoplasty, is it an effective alternative to nasal packing?\n\nContext:\n-OBJECTIVE: To discuss and compare the results of suturing the nasal septum after septoplasty with the results of nasal packing.\n-METHODS: A prospective study, which was performed at Prince Hashem Military Hospital in Zarqa, Jordan and Prince Rashed Military Hospital in Irbid, Jordan between September 2005 and August 2006 included 169 consecutive patients that underwent septoplasty. The patients were randomly divided into 2 groups. After completion of surgery, the nasal septum was sutured in the first group while nasal packing was performed in the second group.\n-RESULTS: Thirteen patients (15.3%) in the first group and 11 patients (13%) in the second group had minor oozing in the first 24 hours, 4 patients (4.8%) had bleeding after removal of the pack in the second group. Four patients (4.8%) developed septal hematoma in the second group. Two patients (2.4%) had septal perforation in the second group. One patient (1.1%) in the first group, and 5 patients (5.9%) in the second group had postoperative adhesions. Five patients (5.9%) were found to have remnant deviated nasal septum in each group. The operating time was 4 minutes longer in the first group.'}]

yes

Suturing of the nasal septum after septoplasty has a comparable effectiveness to nasal packing, with similar rates of minor oozing, bleeding, and septal hematoma, but a longer operating time.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nHave antiepileptic drug prescription claims changed following the FDA suicidality warning?\n\nContext:\n-OBJECTIVE: In January 2008, the Food and Drug Administration (FDA) communicated concerns and, in May 2009, issued a warning about an increased risk of suicidality for all antiepileptic drugs (AEDs). This research evaluated the association between the FDA suicidality communications and the AED prescription claims among members with epilepsy and/or psychiatric disorder.\n-METHODS: A longitudinal interrupted time-series design was utilized to evaluate Oklahoma Medicaid claims data from January 2006 through December 2009. The study included 9289 continuously eligible members with prevalent diagnoses of epilepsy and/or psychiatric disorder and at least one AED prescription claim. Trends, expressed as monthly changes in the log odds of AED prescription claims, were compared across three time periods: before (January 2006 to January 2008), during (February 2008 to May 2009), and after (June 2009 to December 2009) the FDA warning.\n-RESULTS: Before the FDA warning period, a significant upward trend of AED prescription claims of 0.01% per month (99% CI: 0.008% to 0.013%, p<0.0001) was estimated. In comparison to the prewarning period, no significant change in trend was detected during (-20.0%, 99% CI: -70.0% to 30.0%, p=0.34) or after (80.0%, 99% CI: -20.0% to 200.0%, p=0.03) the FDA warning period. After stratification, no diagnostic group (i.e., epilepsy alone, epilepsy and comorbid psychiatric disorder, and psychiatric disorder alone) experienced a significant change in trend during the entire study period (p>0.01).'}]

no

No significant change in trend was detected in AED prescription claims during or after the FDA warning period, compared to the prewarning period.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes ossification of the posterior longitudinal ligament affect the neurological outcome after traumatic cervical cord injury?\n\nContext:\n-STUDY DESIGN: Retrospective outcome measurement study.\n-OBJECTIVES: The purpose of this study is to assess whether ossification of the posterior longitudinal ligament (OPLL) affects neurologic outcomes in patients with acute cervical spinal cord injury (SCI).\n-SUMMARY OF BACKGROUND DATA: There have so far been few reports examining the relationship between OPLL and SCI and there is controversy regarding the deteriorating effects of OPLL-induced canal stenosis on neurologic outcomes.\n-METHODS: To obtain a relatively uniform background, patients nonsurgically treated for an acute C3-C4 level SCI without any fractures or dislocations of the spinal column were selected, resulting in 129 patients. There were 110 men and 19 women (mean age was 61.1 years), having various neurologic conditions on admission (American Spinal Injury Association [ASIA] impairment scale A, 43; B, 16; C, 58; D, 12). The follow-up period was the duration of their hospital stay and ranged from 50 to 603 days (mean, 233 days). The presence of OPLL, the cause of injury, the degree of canal stenosis (both static and dynamic), and the neurologic outcomes in motor function, including improvement rate, were assessed.\n-RESULTS: Of the 129 patients investigated in this study, OPLL was identified at the site of the injury in 13 patients (10.1%). In this OPLL+ group, the static and dynamic canal diameters at C3 and C4 were significantly smaller than those of the remaining 116 patients (OPLL- group). However, no significant difference was observed between the 2 groups in terms of ASIA motor score both at the time of administration and discharge, and the mean improvement rate in ASIA motor score was 55.5 +/- 9.0% in OPLL+ group, while it was 43.1 +/- 2.8% in the OPLL-group. Furthermore, no significant correlation was observed between the static/dynamic canal diameters and neurologic outcome in all 129 patients.'}]

no

No significant difference was observed between the two groups in terms of ASIA motor score both at the time of administration and discharge, and the mean improvement rate in ASIA motor score was similar in both groups.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan distal ureteral diameter predict reflux resolution after endoscopic injection?\n\nContext:\n-OBJECTIVE: To test the predictive value of distal ureteral diameter (UD) on reflux resolution after endoscopic injection in children with primary vesicoureteral reflux (VUR).\n-MATERIALS AND METHODS: This was a retrospective review of patients diagnosed with primary VUR between 2009 and 2012 who were managed by endoscopic injection. Seventy preoperative and postoperative voiding cystourethrograms were reviewed. The largest UD within the false pelvis was measured. The UD was divided by the L1-L3 vertebral body distance to get the UD ratio (UDR). One radiologist interpreted the findings of voiding cystourethrography in all patients. Clinical outcome was defined as reflux resolution.\n-RESULTS: Seventy patients were enrolled in this series (17 boys and 53 girls). Mean age was 5.9 years (1.2-13 years). Grade III presented in 37 patients (53%), and 33 patients (47%) were of grade IV. Mean distal UD was 5.5\xa0mm (2.5-13\xa0mm). Mean UDR was 37.8% (18%-70%). Macroplastique injection was performed in all. Subureteric injection was performed in 60 patients (86%), whereas intraureteric injection was performed in 10 patients. No postoperative complications were detected. The effect of grade, UD, and UDR on success after endoscopic injection was tested. UD and UDR were significant predictors of reflux resolution on logistic regression analysis (P\xa0<.007 and .001, respectively).'}]

yes

Distal ureteral diameter (UD) and UD ratio (UDR) are significant predictors of reflux resolution after endoscopic injection in children with primary vesicoureteral reflux (VUR).

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs leptin involved in phagocytic NADPH oxidase overactivity in obesity?\n\nContext:\n-OBJECTIVES: Hyperleptinemia and oxidative stress play a major role in the development of cardiovascular diseases in obesity. This study aimed to investigate whether there is a relationship between plasma levels of leptin and phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity, and its potential relevance in the vascular remodeling in obese patients.\n-METHODS: The study was performed in 164 obese and 94 normal-weight individuals (controls). NADPH oxidase activity was evaluated by luminescence in phagocytic cells. Levels of leptin were quantified by ELISA in plasma samples. Carotid intima-media thickness (cIMT) was measured by ultrasonography. In addition, we performed in-vitro experiments in human peripheral blood mononuclear cells and murine macrophages.\n-RESULTS: Phagocytic NADPH oxidase activity and leptin levels were enhanced (P<0.05) in obese patients compared with controls. NADPH oxidase activity positively correlated with leptin in obese patients. This association remained significant in a multivariate analysis. cIMT was higher (P<0.05) in obese patients compared with controls. In addition, cIMT also correlated positively with leptin and NADPH oxidase activity in obese patients. In-vitro studies showed that leptin induced NADPH oxidase activation. Inhibition of the leptin-induced NADPH oxidase activity by wortmannin and bisindolyl maleimide suggested a direct involvement of the phosphatidylinositol 3-kinase and protein kinase C pathways, respectively. Finally, leptin-induced NADPH oxidase activation promoted macrophage proliferation.'}]

yes

Leptin is involved in phagocytic NADPH oxidase overactivity in obesity, as evidenced by the positive correlation between leptin levels and NADPH oxidase activity in obese patients, and the in-vitro studies showing that leptin induces NADPH oxidase activation through specific pathways.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCanada\'s Compassionate Care Benefit: is it an adequate public health response to addressing the issue of caregiver burden in end-of-life care?\n\nContext:\n-BACKGROUND: An increasingly significant public health issue in Canada, and elsewhere throughout the developed world, pertains to the provision of adequate palliative/end-of-life (P/EOL) care. Informal caregivers who take on the responsibility of providing P/EOL care often experience negative physical, mental, emotional, social and economic consequences. In this article, we specifically examine how Canada\'s Compassionate Care Benefit (CCB)--a contributory benefits social program aimed at informal P/EOL caregivers--operates as a public health response in sustaining informal caregivers providing P/EOL care, and whether or not it adequately addresses known aspects of caregiver burden that are addressed within the population health promotion (PHP) model.\n-METHODS: As part of a national evaluation of Canada\'s Compassionate Care Benefit, 57 telephone interviews were conducted with Canadian informal P/EOL caregivers in 5 different provinces, pertaining to the strengths and weaknesses of the CCB and the general caregiving experience. Interview data was coded with Nvivo software and emerging themes were identified by the research team, with such findings published elsewhere. The purpose of the present analysis was identified after comparing the findings to the literature specific to caregiver burden and public health, after which data was analyzed using the PHP model as a guiding framework.\n-RESULTS: Informal caregivers spoke to several of the determinants of health outlined in the PHP model that are implicated in their burden experience: gender, income and social status, working conditions, health and social services, social support network, and personal health practises and coping strategies. They recognized the need for improving the CCB to better address these determinants.'}]

maybe

Informal caregivers spoke to several of the determinants of health outlined in the PHP model that are implicated in their burden experience, and they recognized the need for improving the CCB to better address these determinants.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nFatigue in primary Sjögren\'s syndrome: is there a link with the fibromyalgia syndrome?\n\nContext:\n-OBJECTIVE: To determine whether fibromyalgia (FM) is more common in patients with primary Sjögren\'s syndrome (pSS) who complain of fatigue. The association and prevalence of fatigue and FM was recorded in a group of patients with pSS and a control group of lupus patients, a subset of whom had secondary Sjögren\'s syndrome (sSS).\n-METHODS: 74 patients with pSS and 216 patients with lupus were assessed with a questionnaire to identify the presence of fatigue and generalised pain. From the lupus group, in a subset of 117 lupus patients (from the Bloomsbury unit) those with sSS were identified. All patients were studied for the presence of FM.\n-RESULTS: 50 of 74 patients with pSS (68%) reported fatigue-a prevalence significantly higher than in the lupus group (108/216 (50%); p<0.0087). Fatigue was present in 7/13 (54%) patients with SLE/sSS. FM was present in 9/74 patients with pSS (12%), compared with 11/216 lupus patients (5%), and in none of the patients with SLE/sSS. None of these values corresponds with previously reported figures of the incidence of FM in pSS.'}]

no

Fatigue is more common in patients with primary Sjögren's syndrome (pSS) who complain of fatigue, but there is no significant link with the fibromyalgia syndrome (FM) as FM was present in only 12% of patients with pSS, which is not significantly higher than in the lupus group.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs laparoscopic sonography a reliable and sensitive procedure for staging colorectal cancer?\n\nContext:\n-BACKGROUND: Laparoscopic colectomy has developed rapidly with the explosion of technology. In most cases, laparoscopic resection is performed for colorectal cancer. Intraoperative staging during laparoscopic procedure is limited. Laparoscopic ultrasonography (LUS) represents the only real alternative to manual palpation during laparoscopic surgery.\n-METHODS: We evaluated the diagnostic accuracy of LUS in comparison with preoperative staging and laparoscopy in 33 patients with colorectal cancer. Preoperative staging included abdominal US, CT, and endoscopic US (for rectal cancer). Laparoscopy and LUS were performed in all cases. Pre- and intraoperative staging were related to definitive histology. Staging was done according to the TNM classification.\n-RESULTS: LUS obtained good results in the evaluation of hepatic metastases, with a sensitivity of 100% versus 62.5% and 75% by preoperative diagnostic means and laparoscopy, respectively. Nodal metastases were diagnosed with a sensitivity of 94% versus 18% with preoperative staging and 6% with laparoscopy, but the method had a low specificity (53%). The therapeutic program was changed thanks to laparoscopy and LUS in 11 cases (33%). In four cases (12%), the planned therapeutic approach was changed after LUS alone.'}]

yes

Laparoscopic sonography (LUS) is a reliable and sensitive procedure for staging colorectal cancer, with a sensitivity of 100% for hepatic metastases and 94% for nodal metastases, but it has a low specificity of 53%

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs alexithymia a risk factor for unexplained physical symptoms in general medical outpatients?\n\nContext:\n-OBJECTIVE: Alexithymia is presumed to play an important predisposing role in the pathogenesis of medically unexplained physical symptoms. However, no research on alexithymia has been done among general medical outpatients who present with medically unexplained physical symptoms as their main problem and in which anxiety and depression have been considered as possible confounding factors. This study investigated whether patients with medically unexplained physical symptoms are more alexithymic than those with explained symptoms and whether, in patients with unexplained symptoms, alexithymia is associated with subjective health experience and use of medical services.\n-METHODS: We conducted a cross-sectional study among patients attending an internal medicine outpatient clinic. All patients were given a standardized interview and completed a number of questionnaires.\n-RESULTS: After complete physical examinations, 169 of 321 patients had unexplained physical symptoms according to two independent raters. Patients with medically unexplained symptoms more often had a mental disorder, but overall they were not more alexithymic. In patients with unexplained physical symptoms, alexithymia was not associated with subjective health experience or use of medical services. However, patients with both unexplained symptoms and a mental disorder who also denied any possible connection between emotional problems and their physical symptoms did have more alexithymic traits.'}]

no

Alexithymia is not a risk factor for unexplained physical symptoms in general medical outpatients, as patients with unexplained physical symptoms were not more alexithymic overall.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAlcohol consumption and acute myocardial infarction: a benefit of alcohol consumed with meals?\n\nContext:\n-BACKGROUND: The apparent favorable effect of alcohol on the risk of acute myocardial infarction (MI) may be related to its hypoinsulinemic effect when consumed with meals. We studied how the timing of alcohol consumption in relation to meals might affect the risk of MI in a population with relatively high regular alcohol consumption.\n-METHODS: We conducted a case-control study between 1995 and 1999 in Milan, Italy. Cases were 507 subjects with a first episode of nonfatal acute MI, and controls were 478 patients admitted to hospitals for other acute diseases. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by multiple logistic regression models.\n-RESULTS: Compared with nondrinkers, an inverse trend in risk was observed when alcohol was consumed during meals only (for>or =3 drinks per day: OR = 0.50; 95% CI = 0.30-0.82). In contrast, no consistent trend in risk was found for subjects drinking outside of meals (for>or =3 drinks per day: 0.98; 0.49-1.96). The pattern of risk was similar when we considered people who drank only wine.'}]

yes

An inverse trend in risk was observed when alcohol was consumed during meals only, with an odds ratio of 0.50 for those consuming 3 or more drinks per day.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDo mossy fibers release GABA?\n\nContext:\n-PURPOSE: Mossy fibers are the sole excitatory projection from dentate gyrus granule cells to the hippocampus, forming part of the trisynaptic hippocampal circuit. They undergo significant plasticity during epileptogenesis and have been implicated in seizure generation. Mossy fibers are a highly unusual projection in the mammalian brain; in addition to glutamate, they release adenosine, dynorphin, zinc, and possibly other peptides. Mossy fiber terminals also show intense immunoreactivity for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), and immunoreactivity for GAD67. The purpose of this review is to present physiologic evidence of GABA release by mossy fibers and its modulation by epileptic activity.\n-METHODS: We used hippocampal slices from 3- to 5-week-old guinea pigs and made whole-cell voltage clamp recordings from CA3 pyramidal cells. We placed stimulating electrodes in stratum granulosum and adjusted their position in order to recruit mossy fiber to CA3 projections.\n-RESULTS: We have shown that electrical stimuli that recruit dentate granule cells elicit monosynaptic GABAA receptor-mediated synaptic signals in CA3 pyramidal neurons. These inhibitory signals satisfy the criteria that distinguish mossy fiber-CA3 synapses: high sensitivity to metabotropic glutamate-receptor agonists, facilitation during repetitive stimulation, and N-methyl-D-aspartate (NMDA) receptor-independent long-term potentiation.'}]

yes

Mossy fibers release GABA, as shown by the intense immunoreactivity for GABA and GAD67 in mossy fiber terminals and the elicitation of monosynaptic GABAA receptor-mediated synaptic signals in CA3 pyramidal neurons.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nThe clinical significance of bile duct sludge: is it different from bile duct stones?\n\nContext:\n-BACKGROUND: Some patients with suspected common bile duct (CBD) stones are found to have sludge and no stones. Although sludge in the gallbladder is a precursor of gallbladder stones, the significance of bile duct sludge (BDS) is poorly defined. This study aimed to compare BDS with bile duct stones in terms of frequency, associated risk factors, and clinical outcome after endoscopic therapy.\n-METHODS: The study enrolled 228 patients who underwent therapeutic endoscopic retrograde cholangiopancreatography (ERCP) for suspected choledocholithiasis. The patients were divided into two groups: patients with BDS but no stones on ERCP and patients with CBD stones. The presence of risk factors for bile duct stones (age, periampullary diverticulum, ductal dilation or angulation, previous open cholecystectomy) were assessed at ERCP. Follow-up data (36 +/- 19 months) were obtained from medical records and by patient questioning.\n-RESULTS: Bile duct sludge occurred in 14% (31/228) of patients and was more common in females. After endoscopic clearance, CBD stones recurred in 17% (33/197) of the patients with CBD stones, and in 16% (5/31) of the patients with BDS (p = 0.99). Common bile duct dilation was less common in the sludge group. The other known risk factors for recurrent CBD stones (age, previous open cholecystectomy, bile duct angulation, and the presence of a peripampullary diverticulum) were not statistically different between the two groups.'}]

no

The clinical significance of bile duct sludge is not significantly different from bile duct stones in terms of recurrence of CBD stones after endoscopic therapy.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan Ambu self-inflating bag and Neopuff infant resuscitator provide adequate and safe manual inflations for infants up to 10\u2005kg weight?\n\nContext:\n-BACKGROUND: Manual resuscitation devices for infants and newborns must be able to provide adequate ventilation in a safe and consistent manner across a wide range of patient sizes (0.5-10\u2005kg) and differing clinical states. There are little comparative data assessing biomechanical performance of common infant manual resuscitation devices across the manufacturers\' recommended operating weight ranges. We aimed to compare performance of the Ambu self-inflating bag (SIB) with the Neopuff T-piece resuscitator in three resuscitation models.\n-METHODS: Five experienced clinicians delivered targeted ventilation to three lung models differing in compliance, delivery pressures and inflation rates; Preterm (0.5\u2005mL/cmH2O, 25/5 cmH2O, 60 per minute), Term (3\u2005mL/cmH2O, 30/5 cmH2O, 40 per minute) and Infant (9\u2005mL/cmH2O, 35/5 cmH2O, 30 per minute). The Neopuff was examined with three gas inflow rates (5 litres per minute (LPM), 10 LPM and 15 LPM) and the Ambu with no gas inflow.\n-RESULTS: 3309 inflations were collected and analysed with analysis of variance for repeated measures. The Neopuff was unable to reach set peak inflation pressures and exhibited seriously elevated positive end expiratory pressure (PEEP) with all inflow gas rates (p<0.001) in this infant model. The Ambu SIB accurately delivered targeted pressures in all three models.'}]

yes

The Ambu self-inflating bag accurately delivered targeted pressures in all three models, but the Neopuff infant resuscitator was unable to reach set peak inflation pressures and exhibited seriously elevated positive end expiratory pressure (PEEP) with all inflow gas rates in the infant model.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAre IgM-enriched immunoglobulins an effective adjuvant in septic VLBW infants?\n\nContext:\n-METHODS: All VLBW infants from January 2008 to December 2012 with positive blood culture beyond 72 hours of life were enrolled in a retrospective cohort study. Newborns born after June 2010 were treated with IgM-eIVIG, 250 mg/kg/day iv for three days in addition to standard antibiotic regimen and compared to an historical cohort born before June 2010, receiving antimicrobial regimen alone. Short-term mortality (i.e. death within 7 and 21 days from treatment) was the primary outcome. Secondary outcomes were: total mortality, intraventricular hemorrhage, necrotizing enterocolitis, periventricular leukomalacia, bronchopulmonary dysplasia at discharge.\n-RESULTS: 79 neonates (40 cases) were enrolled. No difference in birth weight, gestational age or SNAP II score (disease severity score) were found. Significantly reduced short-term mortality was found in treated infants (22% vs 46%; p = 0.005) considering all microbial aetiologies and the subgroup affected by Candida spp. Secondary outcomes were not different between groups.'}]

yes

IgM-enriched immunoglobulins (IgM-eIVIG) were found to be effective in reducing short-term mortality in septic VLBW infants, with a significant reduction in mortality rate from 46% to 22%.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs resected stomach volume related to weight loss after laparoscopic sleeve gastrectomy?\n\nContext:\n-BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) was initially performed as the first stage of biliopancreatic diversion with duodenal switch for the treatment of super-obese or high-risk obese patients but is now most commonly performed as a standalone operation. The aim of this prospective study was to investigate outcomes after LSG according to resected stomach volume.\n-METHODS: Between May 2011 and April 2013, LSG was performed in 102 consecutive patients undergoing bariatric surgery. Two patients were excluded, and data from the remaining 100 patients were analyzed in this study. Patients were divided into three groups according to the following resected stomach volume: 700-1,200 mL (group A, n\u2009=\u200921), 1,200-1,700 mL (group B, n\u2009=\u200962), and>1,700 mL (group C, n\u2009=\u200917). Mean values were compared among the groups by analysis of variance.\n-RESULTS: The mean percentage excess body weight loss (%EBWL) at 3, 6, 12, and 24 months after surgery was 37.68\u2009±\u200910.97, 50.97\u2009±\u200913.59, 62.35\u2009±\u200911.31, and 67.59\u2009±\u20099.02 %, respectively. There were no significant differences in mean %EBWL among the three groups. Resected stomach volume was greater in patients with higher preoperative body mass index and was positively associated with resected stomach weight.'}]

no

There were no significant differences in mean %EBWL among the three groups, indicating that resected stomach volume is not significantly related to weight loss after laparoscopic sleeve gastrectomy.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nResection of colorectal liver metastases after second-line chemotherapy: is it worthwhile?\n\nContext:\n-PURPOSE: Patient outcome after resection of colorectal liver metastases (CLM) following second-line preoperative chemotherapy (PCT) performed for insufficient response or toxicity of the first-line, is little known and has here been compared to the outcome following first-line.\n-PATIENTS AND METHODS: From January 2005 to June 2013, 5624 and 791 consecutive patients of a prospective international cohort received 1 and 2 PCT lines before CLM resection (group 1 and 2, respectively). Survival and prognostic factors were analysed.\n-RESULTS: After a mean follow-up of 30.1 months, there was no difference in survival from CLM diagnosis (median, 3-, and 5-year overall survival [OS]: 58.6 months, 76% and 49% in group 2 versus 58.9 months, 71% and 49% in group 1, respectively, P\xa0=\xa00.32). After hepatectomy, disease-free survival (DFS) was however shorter in group 2: 17.2 months, 27% and 15% versus 19.4 months, 32% and 23%, respectively (P\xa0=\xa00.001). Among the initially unresectable patients of group 1 and 2, no statistical difference in OS or DFS was observed. Independent predictors of worse OS in group 2 were positive primary lymph nodes, extrahepatic disease, tumour progression on second line, R2 resection\xa0and number of hepatectomies/year<50. Positive primary nodes, synchronous and bilateral metastases were predictors of shorter DFS. Initial unresectability did not impact OS or DFS in group 2.'}]

maybe

The study found that the survival rate from colorectal liver metastases diagnosis was not significantly different between patients who received second-line preoperative chemotherapy and those who received first-line chemotherapy, with a median overall survival of 58.6 months and 58.9 months, respectively. However, the disease-free survival after hepatectomy was shorter in the second-line group, with 17.2 months, 27% and 15% versus 19.4 months, 32% and 23% in the first-line group.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDo ART patients face higher C-section rates during their stage of delivery?\n\nContext:\n-PURPOSE: The mode of delivery depends on multiple parameters. After assisted reproductive technology (ART), previous studies have shown elevated C-section rates but few studies differentiated between elective and emergency operations and different protocols of cryopreservation. Because these studies did not use multiparity as exclusion criteria which reduces confounding with previous pregnancies, aim of this study is to compare mode of delivery of different techniques of ART using data of primiparae only [1, 2].\n-METHODS: Retrospective analysis of patient data treated at the university hospital of Luebeck in a period of 12 years. Patients were divided in different groups according to their way of conception: spontaneous conception and conception after\xa0ART. The group of ART was further divided into: (a) a group of fresh transferred embryos (IVF/ICSI), (b) vitrification and (c) slow freezing. Exclusion criteria were defined as: multiparity, delivery<24.\xa0+\xa00\xa0p.m., incomplete data and treatment outside university of Luebeck. Main parameter of this study was mode of delivery which was divided into spontaneous delivery or C-section. C-sections were further differentiated into elective or emergency C-sections.\n-RESULTS: The group of fresh transferred embryos and slow freezing showed higher risks for elective and emergency C-sections (elective C-sections odds ratio 2.0, CI 95% 1.6-2.6, emergency C-sections odds ratio 1.4, CI 95% 1.1-1.9). Moreover, all groups of ART show enhanced risk of significant perinatal bleeding.'}]

yes

The group of fresh transferred embryos and slow freezing showed higher risks for elective and emergency C-sections.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes a preoperative medically supervised weight loss program improve bariatric surgery outcomes?\n\nContext:\n-BACKGROUND: Many insurance payors mandate that bariatric surgery candidates undergo a medically supervised weight management (MSWM) program as a prerequisite for surgery. However, there is little evidence to support this requirement. We evaluated in a randomized controlled trial the hypothesis that participation in a MSWM program does not predict outcomes after laparoscopic adjustable gastric banding (LAGB) in a publicly insured population.\n-METHODS: This pilot randomized trial was conducted in a large academic urban public hospital. Patients who met NIH consensus criteria for bariatric surgery and whose insurance did not require a mandatory 6-month MSWM program were randomized to a MSWM program with monthly visits over 6 months (individual or group) or usual care for 6 months and then followed for bariatric surgery outcomes postoperatively. Demographics, weight, and patient behavior scores, including patient adherence, eating behavior, patient activation, and physical activity, were collected at baseline and at 6 months (immediately preoperatively and postoperatively).\n-RESULTS: A total of 55 patients were enrolled in the study with complete follow-up on 23 patients. Participants randomized to a MSWM program attended an average of 2 sessions preoperatively. The majority of participants were female and non-Caucasian, mean age was 46 years, average income was less than $20,000/year, and most had Medicaid as their primary insurer, consistent with the demographics of the hospital\'s bariatric surgery program. Data analysis included both intention-to-treat and completers\' analyses. No significant differences in weight loss and most patient behaviors were found between the two groups postoperatively, suggesting that participation in a MSWM program did not improve weight loss outcomes for LAGB. Participation in a MSWM program did appear to have a positive effect on physical activity postoperatively.'}]

no

No significant differences in weight loss and most patient behaviors were found between the two groups postoperatively, suggesting that participation in a MSWM program did not improve weight loss outcomes for LAGB.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs solitary kidney really more resistant to ischemia?\n\nContext:\n-PURPOSE: To our knowledge there are no evidence-based medicine data to date to critically judge the vulnerability of a solitary kidney to warm ischemia compared to paired kidneys.\n-MATERIALS AND METHODS: Ten dogs were exposed to open right nephrectomy to create a solitary kidney model (group 1). Ten dogs with both kidneys were considered group 2. All dogs underwent warm ischemia by open occlusion of the left renal artery for 90 minutes. Dogs were sacrificed at different intervals (3 days to 4 weeks). All dogs were reevaluated by renogram before sacrifice and histopathology of the investigated kidney. The proinflammatory markers CD95 and tumor necrosis factor-α were assessed using real-time polymerase chain reaction.\n-RESULTS: In group 1 clearance decreased by 20% at 1 week but basal function was regained starting at week 2. In group 2 clearance decreased more than 90% up to week 2. Recovery started at week 3 and by 4 weeks there was a 23% clearance reduction. Histopathological examination in group 1 revealed significant tubular necrosis (60%) at 3 days with regeneration starting at 1 week. In group 2 there was more pronounced tubular necrosis (90%) with regeneration starting at 2 weeks. The expression of proinflammatory markers was up-regulated in each group with higher, more sustained expression in group 2.'}]

yes

The study found that a solitary kidney has a better recovery rate after warm ischemia compared to paired kidneys, with a 20% decrease in clearance at 1 week in group 1 versus a 90% decrease in clearance at week 2 in group 2.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nNeck pain treatment with acupuncture: does the number of needles matter?\n\nContext:\n-OBJECTIVES: Acupuncture has been successfully used in myofascial pain syndromes. However, the number of needles used, that is, the dose of acupuncture stimulation, to obtain the best antinociceptive efficacy is still a matter of debate. The question was addressed comparing the clinical efficacy of two different therapeutic schemes, characterized by a different number of needles used on 36 patients between 29-60 years of age with by a painful cervical myofascial syndrome.\n-METHODS: Patients were divided into two groups; the first group of 18 patients were treated with 5 needles and the second group of 18 patients were treated with 11 needles, the time of needle stimulation was the same in both groups: 100 seconds. Each group underwent six cycles of somatic acupuncture. Pain intensity was evaluated before, immediately after and 1 and 3 months after the treatment by means of both the Mc Gill Pain Questionnaire and the Visual Analogue Scale (VAS). In both groups, the needles were fixed superficially excluding the two most painful trigger points where they were deeply inserted.\n-RESULTS: Both groups, independently from the number of needles used, obtained a good therapeutic effect without clinically relevant differences.'}]

no

Both groups, independently from the number of needles used, obtained a good therapeutic effect without clinically relevant differences.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes fluoridation reduce the use of dental services among adults?\n\nContext:\n-OBJECTIVES: The authors determine whether prevention influences the use of health services. Fluoridation\'s effect on restorative dental demand among 972 Washington state employees and spouses, aged 20 to 34 years, in two fluoridated communities and a nonfluoridated community was examined.\n-METHODS: At baseline, adults were interviewed by telephone, and oral assessments were conducted to measure personal characteristics, lifetime exposure to fluoridated water, oral disease, and the quality of restorations. Adults were followed for 2 years to measure dental demand from dental claims. Each adult\'s baseline and claims data were linked with provider and practice variables collected from the dentist who provided treatment.\n-RESULTS: Relative to adults with no lifetime exposure to fluoridated water, adults drinking fluoridated water for half or more of their lives had less disease at baseline and a lower but nonsignificant probability of receiving a restoration in the follow-up period. In the 2-year follow-up period, however, more than half of the restorations were performed to replace fillings of satisfactory or ideal quality at baseline. When only teeth with decay and unsatisfactory fillings at baseline were considered, adults with high fluoridation exposure had a lower probability of receiving a restoration than adults with no exposure. Market effects also were detected in demand equations; relative to adults in the nonfluoridated community, adults residing in the fluoridated community with a large dentist supply received a greater number of restorations, suggesting potential supplier-induced demand from less disease and fewer patients.'}]

yes

Fluoridation is associated with a lower probability of receiving a restoration among adults, particularly when only teeth with decay and unsatisfactory fillings at baseline are considered.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nPertrochanteric fractures: is there an advantage to an intramedullary nail?\n\nContext:\n-OBJECTIVES: To compare the results between a sliding compression hip screw and an intramedullary nail in the treatment of pertrochanteric fractures.\n-DESIGN: Prospective computer-generated randomization of 206 patients into two study groups: those treated by sliding compression hip screw (Group 1; n = 106) and those treated by intramedullary nailing (Group 2; n = 100).\n-SETTING: University Level I trauma center.\n-PATIENTS: All patients over the age of fifty-five years presenting with fractures of the trochanteric region caused by a low-energy injury, classified as AO/OTA Type 31-A1 and A2.\n-INTERVENTION: Treatment with a sliding compression hip screw (Dynamic Hip Screw; Synthes-Stratec, Oberdorf, Switzerland) or an intramedullary nail (Proximal Femoral Nail; Synthes-Stratec, Oberdorf, Switzerland).\n-MAIN OUTCOME MEASUREMENTS: Intraoperative: operative and fluoroscopy times, the difficulty of the operation, intraoperative complications, and blood loss. Radiologic: fracture healing and failure of fixation. Clinical: pain, social functioning score, and mobility score.\n-RESULTS: The minimum follow-up was one year. We did not find any statistically significant difference, intraoperatively, radiologically, or clinically, between the two groups of patients.'}]

no

The study found no statistically significant difference between the use of a sliding compression hip screw and an intramedullary nail in the treatment of pertrochanteric fractures, indicating no advantage of one over the other.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nSPECT study with I-123-Ioflupane (DaTSCAN) in patients with essential tremor. Is there any correlation with Parkinson\'s disease?\n\nContext:\n-OBJECTIVES: The differential diagnosis between essential tremor (ET) and Parkinson\'s disease (PD) may be, in some cases, very difficult on clinical grounds alone. In addition, it is accepted that a small percentage of ET patients presenting symptoms and signs of possible PD may progress finally to a typical pattern of parkinsonism. Ioflupane, N-u-fluoropropyl-2a-carbomethoxy-3a-(4-iodophenyl) nortropane, also called FP-CIT, labelled with (123)I (commercially known as DaTSCAN) has been proven to be useful in the differential diagnosis between PD and ET and to confirm dopaminergic degeneration in patients with parkinsonism. The aim of this study is to identify dopaminergic degeneration in patients with PD and distinguish them from others with ET using semi-quantitative SPECT (123)I-Ioflupane (DaTSCAN) data in comparison with normal volunteers (NV), in addition with the respective ones of patients referred as suffering from ET, as well as, of patients with a PD diagnosis at an initial stage with a unilateral presentation of motor signs.\n-METHODS: Twenty-eight patients suffering from ET (10 males plus 18 females) and 28 NV (12 males and 16 females) were enroled in this study. In addition, 33 patients (11 males and 22 females) with an established diagnosis of PD with unilateral limb involvement (12 left hemi-body and 21 right hemi-body) were included for comparison with ET. We used DaTSCAN to obtain SPECT images and measure the radiopharmaceutical uptake in the striatum (S), as well as the caudate nucleus (CN) and putamen (P) in all individuals.\n-RESULTS: Qualitative (Visual) interpretation of the SPECT data did not find any difference in the uptake of the radiopharmaceutical at the level of the S, CN and P between NV and ET patients. Reduced accumulation of the radiopharmaceutical uptake was found in the P of all PD patients. Semiquantitative analysis revealed significant differences between NV and ET patients in the striatum, reduced in the latter. There was also a significant reduction in the tracer accumulation in the left putamen of patients with right hemi-parkinsonism compared to ET and NV. Patients with left hemi-parkinsonism, demonstrated reduced radioligand uptake in the right putamen in comparison with ET and NV. Clinical follow-up of 20 patients with ET at (so many months afterwards) revealed no significant change in clinical presentation, particularly no signs of PD. Follow-up DaTSCAN performed in 10 of them (so many months afterwards) was negative in all but one. This one had an equivocal baseline study which deteriorated 12\xa0months later.'}]

no

The study found that qualitative and semiquantitative analysis of SPECT study with I-123-Ioflupane (DaTSCAN) in patients with essential tremor (ET) did not show any correlation with Parkinson's disease (PD) at the time of the study, as no significant difference was found in the uptake of the radiopharmaceutical at the level of the striatum, caudate nucleus, and putamen between ET patients and normal volunteers.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAre the GFRUP\'s recommendations for withholding or withdrawing treatments in critically ill children applicable?\n\nContext:\n-OBJECTIVE: To evaluate feasibility of the guidelines of the Groupe Francophone de Réanimation et Urgence Pédiatriques (French-speaking group of paediatric intensive and emergency care; GFRUP) for limitation of treatments in the paediatric intensive care unit (PICU).\n-DESIGN: A 2-year prospective survey.\n-SETTING: A 12-bed PICU at the Hôpital Jeanne de Flandre, Lille, France.\n-PATIENTS: Were included when limitation of treatments was expected.\n-RESULTS: Of 967 children admitted, 55 were included with a 2-day median delay. They were younger than others (24 v 60 months), had a higher paediatric risk of mortality (PRISM) score (14 v 4), and a higher paediatric overall performance category (POPC) score at admission (2 v 1); all p<0.002. 34 (50% of total deaths) children died. A limitation decision was made without meeting for 7 children who died: 6 received do-not-resuscitate orders (DNROs) and 1 received withholding decision. Decision-making meetings were organised for 31 children, and the following decisions were made: 12 DNROs (6 deaths and 6 survivals), 4 withholding (1 death and 3 survivals), with 14 withdrawing (14 deaths) and 1 continuing treatment (survival). After limitation, 21 (31% of total deaths) children died and 10 survived (POPC score 4). 13 procedures were interrupted because of death and 11 because of clinical improvement (POPC score 4). Parents\' opinions were obtained after 4 family conferences (for a total of 110 min), 3 days after inclusion. The first meeting was planned for 6 days after inclusion and held on the 7th day after inclusion; 80% of parents were immediately informed of the decision, which was implemented after half a day.'}]

yes

The GFRUP's recommendations for withholding or withdrawing treatments in critically ill children were applicable in 50% of total deaths, with 34 children dying after a limitation decision was made.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs inhaled prophylactic heparin useful for prevention and Management of Pneumonia in ventilated ICU patients?\n\nContext:\n-PURPOSE: To determine whether prophylactic inhaled heparin is effective for the prevention and treatment of pneumonia patients receiving mechanical ventilation (MV) in the intensive care unit.\n-METHODS: A phase 2, double blind randomized controlled trial stratified for study center and patient type (non-operative, post-operative) was conducted in three university-affiliated intensive care units. Patients aged ≥18years and requiring invasive MV for more than 48hours were randomized to usual care, nebulization of unfractionated sodium heparin (5000 units in 2mL) or placebo nebulization with 0.9% sodium chloride (2mL) four times daily with the main outcome measures of the development of ventilator associated pneumonia (VAP), ventilator associated complication (VAC) and sequential organ failure assessment scores in patients with pneumonia on admission or who developed VAP.\n-TRIAL REGISTRATION: Australian and New Zealand Clinical Trials Registry ACTRN12612000038897.\n-RESULTS: Two hundred and fourteen patients were enrolled (72 usual care, 71 inhaled sodium heparin, 71 inhaled sodium chloride). There were no differences between treatment groups in terms of the development of VAP, using either Klompas criteria (6-7%, P=1.00) or clinical diagnosis (24-26%, P=0.85). There was no difference in the clinical consistency (P=0.70), number (P=0.28) or the total volume of secretions per day (P=.54). The presence of blood in secretions was significantly less in the usual care group (P=0.005).'}]

no

There were no differences between treatment groups in terms of the development of ventilator-associated pneumonia (VAP) using either Klompas criteria or clinical diagnosis.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs the h-index predictive of greater NIH funding success among academic radiologists?\n\nContext:\n-RATIONALE AND OBJECTIVES: Despite rapid adoption of the Hirsch index (h-index) as a measure of academic success, the correlations between the h-index and other metrics of productivity remain poorly understood. The aims of this study were to determine whether h-indices were associated with greater National Institutes of Health (NIH) funding success among academic radiologists.\n-MATERIALS AND METHODS: Using the Scopus database, h-indices were calculated for a random sample of academic radiologists with the rank of professor. Using the NIH tool Research Portfolio Online Reporting Tools Expenditures and Reports, we determined the number, classification, and total years of NIH grant funding as principal investigator for each radiologist. Differences in h-index, sorted by funding status, were determined using Wilcoxon\'s tests. Associations between h-index and funding status were determined using logistic regression. Significant correlations between h-index and grant metrics were determined using Spearman\'s ρ.\n-RESULTS: Among 210 professors of radiology, 48 (23%) secured at least one NIH grant. The mean h-index was significantly higher among individuals who secured at least one NIH grant (19.1) compared to those who did not (10.4) (P<.0001). Professors with h-indices<10 compared to those with h-indices>10 were significantly less likely to receive NIH funding (odds ratio, 0.07; P = .0321). However, h-indices>10 were not significantly predictive of greater funding. No significant relationships were observed between h-index and the number of grant awards, years of prior funding, the amounts of grant awards, or grant classification.'}]

maybe

The h-index is not significantly predictive of greater NIH funding success among academic radiologists, but professors with h-indices>10 were significantly more likely to receive NIH funding compared to those with h-indices<10.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs minimally invasive mitral valve repair with artificial chords reproducible and applicable in routine surgery?\n\nContext:\n-OBJECTIVES: Traditional resectional techniques and chordal transfer are difficult to apply in video-assisted mitral valve repair. Using artificial chords appears easier in this setting. The purpose of this study was to review the effectiveness and reproducibility of neochordal repair as a routine approach to minimally invasive mitral repair, and to assess the stability of neochord implantation using the figure-of-eight suture without pledgets in this setting.\n-METHODS: This is a retrospective review of all patients who underwent minimally invasive video-assisted mitral valve repair from 2008 to 2013. The primary endpoints were recurrent mitral regurgitation and reoperation.\n-RESULTS: A total of 426 consecutive patients were included during the study period, with a mean age of 55 ± 18 years. Neochords were used in all patients, and in association with leaflet resection in 47 patients. One patient was not repairable and underwent valve replacement (repair rate, 99.8%). Fifteen patients had Grade I (3.5%) regurgitation, whereas the remainder had none. Patients were fast-tracked, with 25% extubated in the operation theatre and the remainder within 6 h. There were 5 deaths within 30 days (1.2%). Follow-up ranged 3-60 months, during which all of the patients remained with no or trace mitral regurgitation. No de-insertion or rupture of any neochords was found, and no patients required a reoperation.'}]

yes

Minimally invasive mitral valve repair with artificial chords is reproducible and applicable in routine surgery, with a high repair rate (99.8%) and low rate of recurrent mitral regurgitation (3.5%) and reoperation.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes obesity predict knee pain over fourteen years in women, independently of radiographic changes?\n\nContext:\n-OBJECTIVE: To examine longitudinal patterns in body mass index (BMI) over 14 years and its association with knee pain in the Chingford Study.\n-METHODS: We studied a total of 594 women with BMI data from clinic visits at years (Y) 1, 5, 10, and 15. Knee pain at Y15 was assessed by questionnaire. Associations between BMI over 14 years and knee pain at Y15 were examined using logistic regression.\n-RESULTS: BMI significantly increased from Y1 to Y15 (P<0.0005) with medians (interquartile ranges) of 24.5 kg/m(2) (22.5-27.2 kg/m(2) ) and 26.5 kg/m(2) (23.9-30.1 kg/m(2) ), respectively. At Y15, 45.1% of subjects had knee pain. A greater BMI at Y1 (odds ratio [OR] 1.34, 95% confidence interval [95% CI]1.05-1.69), at Y15 (OR 1.34, 95% CI 1.10-1.61), and change in BMI over 15 years (OR 1.40, 95% CI 1.00-1.93) were significant predictors of knee pain at Y15 (P<0.05). BMI change was associated with bilateral (OR 1.61, 95% CI 1.05-1.76, P = 0.024) but not unilateral knee pain (OR 1.22, 95% CI 0.73-1.76, P = 0.298). The association between BMI change and knee pain was independent of radiographic knee osteoarthritis (OA). The strength of association between BMI and knee pain at Y15 was similar during followup measurements.'}]

yes

A greater BMI at the beginning of the study (Y1), at the end of the study (Y15), and the change in BMI over 15 years were significant predictors of knee pain at Y15, and the association between BMI change and knee pain was independent of radiographic knee osteoarthritis (OA).

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDo liquid-based preparations of urinary cytology perform differently than classically prepared cases?\n\nContext:\n-CONTEXT: The cytomorphology of liquid-based preparations in urine cytology is different than classic slide preparations.\n-OBJECTIVES: To compare the performance of liquid-based preparation specimens to classically prepared urine specimens with a malignant diagnosis in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology.\n-DESIGN: Participant responses between 2000 and 2007 for urine specimens with a reference diagnosis of high-grade urothelial carcinoma/carcinoma in situ/dysplasia (HGUCA), squamous cell carcinoma, or adenocarcinoma were evaluated. ThinPrep and SurePath challenges were compared with classic preparations (smears, cytospins) for discordant responses.\n-RESULTS: There were 18 288 pathologist, 11 957 cytotechnologist, and 8086 "laboratory" responses available. Classic preparations comprised 90% (n = 34 551) of urine challenges; 9% (n = 3295) were ThinPrep and 1% (n = 485) were SurePath. Concordance to the general category of "positive-malignant" was seen in 92% of classic preparations, 96.5% of ThinPrep, and 94.6% of SurePath challenges (P<.001). These results were statistically different for the exact reference interpretation of HGUCA (P<.001) but not for adenocarcinoma (P = .22). Cytotechnologists demonstrate statistically better performance for the general category of "positive-malignant" compared with pathologists for all urinary slide types and for the exact reference interpretation of HGUCA (94% versus 91.1%; P<.001) but not adenocarcinoma (96.3% versus 95.8%; P = .77) or squamous cell carcinoma (93.6% versus 87.7%; P = .07).'}]

yes

Yes, liquid-based preparations of urinary cytology perform differently than classically prepared cases, with higher concordance rates for the general category of 'positive-malignant' and exact reference interpretation of high-grade urothelial carcinoma/carcinoma in situ/dysplasia.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nOutcomes of severely injured adult trauma patients in an Australian health service: does trauma center level make a difference?\n\nContext:\n-BACKGROUND: Trauma centers are designated to provide systematized multidisciplinary care to injured patients. Effective trauma systems reduce patient mortality by facilitating the treatment of injured patients at appropriately resourced hospitals. Several U.S. studies report reduced mortality among patients admitted directly to a level I trauma center compared with those admitted to hospitals with less resources. It has yet to be shown whether there is an outcome benefit associated with the "level of hospital" initially treating severely injured trauma patients in Australia. This study was designed to determine whether the level of trauma center providing treatment impacts mortality and/or hospital length of stay.\n-METHODS: Outcomes were evaluated for severely injured trauma patients with an Injury Severity Score (ISS)>15 using NSW Institute of Trauma and Injury Management data from 2002-2007 for our regional health service. To assess the association between trauma centers and binary outcomes, a logistic regression model was used. To assess the association between trauma centers and continuous outcomes, a multivariable linear regression model was used. Sex, age, and ISS were included as covariates in all models.\n-RESULTS: There were 1,986 trauma presentations during the 6-year period. Patients presenting to a level III trauma center had a significantly higher risk of death than those presenting to the level I center, regardless of age, sex, ISS, or prehospital time. Peer review of deaths at the level III center identified problems in care delivery in 15 cases associated with technical errors, delay in decision making, or errors of judgement.'}]

yes

Patients presenting to a level III trauma center had a significantly higher risk of death than those presenting to the level I center, regardless of age, sex, ISS, or prehospital time.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes a well developed collateral circulation predispose to restenosis after percutaneous coronary intervention?\n\nContext:\n-OBJECTIVE: To evaluate whether a well developed collateral circulation predisposes to restenosis after percutaneous coronary intervention (PCI).\n-DESIGN: Prospective observational study.\n-PATIENTS AND SETTING: 58 patients undergoing elective single vessel PCI in a tertiary referral interventional cardiac unit in the UK.\n-METHODS: Collateral flow index (CFI) was calculated as (Pw-Pv)/(Pa-Pv), where Pa, Pw, and Pv are aortic, coronary wedge, and right atrial pressures during maximum hyperaemia. Collateral supply was considered poor (CFI<0.25) or good (CFI>or = 0.25).\n-MAIN OUTCOME MEASURES: In-stent restenosis six months after PCI, classified as neointimal volume>or = 25% stent volume on intravascular ultrasound (IVUS), or minimum lumen area<or = 50% stent area on IVUS, or minimum lumen diameter<or = 50% reference vessel diameter on quantitative coronary angiography.\n-RESULTS: Patients with good collaterals had more severe coronary stenoses at baseline (90 (11)% v 75 (16)%, p<0.001). Restenosis rates were similar in poor and good collateral groups (35% v 43%, p = 0.76 for diameter restenosis, 27% v 45%, p = 0.34 for area restenosis, and 23% v 24%, p = 0.84 for volumetric restenosis). CFI was not correlated with diameter, area, or volumetric restenosis (r2<0.1 for each). By multivariate analysis, stent diameter, stent length,>10% residual stenosis, and smoking history were predictive of restenosis.'}]

no

Restenosis rates were similar in poor and good collateral groups, and CFI was not correlated with diameter, area, or volumetric restenosis.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAre home sampling kits for sexually transmitted infections acceptable among men who have sex with men?\n\nContext:\n-OBJECTIVE: There is an urgent need to increase opportunistic screening for sexually transmitted infections (STIs) in community settings, particularly for those who are at increased risk including men who have sex with men (MSM). The aim of this qualitative study was to explore whether home sampling kits (HSK) for multiple bacterial STIs are potentially acceptable among MSM and to identify any concerns regarding their use. This study was developed as part of a formative evaluation of HSKs.\n-METHODS: Focus groups and one-to-one semi-structured interviews with MSM were conducted. Focus group participants (n = 20) were shown a variety of self-sampling materials and asked to discuss them. Individual interviewees (n = 24) had experience of the self-sampling techniques as part of a pilot clinical study. All data were digitally recorded and transcribed verbatim. Data were analysed using a framework analysis approach.\n-RESULTS: The concept of a HSK was generally viewed as positive, with many benefits identified relating to increased access to testing, enhanced personal comfort and empowerment. Concerns about the accuracy of the test, delays in receiving the results, the possible lack of support and potential negative impact on \'others\' were raised.'}]

yes

The concept of a home sampling kit for sexually transmitted infections was generally viewed as positive among men who have sex with men, with many benefits identified relating to increased access to testing, enhanced personal comfort and empowerment.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes route of delivery affect maternal and perinatal outcome in women with eclampsia?\n\nContext:\n-OBJECTIVE: The route of delivery in eclampsia is controversial. We hypothesized that adverse maternal and perinatal outcomes may not be improved by early cesarean delivery.\n-STUDY DESIGN: This was a randomized controlled exploratory trial carried out in a rural teaching institution. In all, 200 eclampsia cases, carrying ≥34 weeks, were allocated to either cesarean or vaginal delivery. Composite maternal and perinatal event rates (death and severe morbidity) were compared by intention-to-treat principle.\n-RESULTS: Groups were comparable at baseline with respect to age and key clinical parameters. Maternal event rate was similar: 10.89% in the cesarean arm vs 7.07% for vaginal delivery (relative risk, 1.54; 95% confidence interval, 0.62-3.81). Although the neonatal event rate was less in cesarean delivery-9.90% vs 19.19% (relative risk, 0.52; 95% confidence interval, 0.25-1.05)-the difference was not significant statistically.'}]

no

The study found that the route of delivery does not significantly affect maternal and perinatal outcome in women with eclampsia, as the maternal event rate was similar between cesarean and vaginal delivery, and the difference in neonatal event rate was not statistically significant.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nSurgical management of the atherosclerotic ascending aorta: is endoaortic balloon occlusion safe?\n\nContext:\n-BACKGROUND: Occlusion of the atherosclerotic ascending aorta by an endoaortic inflatable balloon has been proposed as an alternative to conventional cross-clamping to prevent injury to the vessel and distal embolization of debris. The safety and the effectiveness of endoaortic occlusion have not been documented in this setting.\n-METHODS: Endoaortic occlusion was employed in 52 of 2,172 consecutive patients. Surgeon\'s choice was based on preoperative identification of aortic calcifications or intraoperative epiaortic ultrasonographic scanning. Deaths and strokes were analyzed casewise and in aggregate.\n-RESULTS: In 10 patients (19.2%), the endoaortic balloon had to be replaced by the ordinary cross-clamp because of incomplete occlusion (n = 5), hindered exposure (n = 2), or balloon rupture (n = 3). In-hospital death occurred in 13 patients (25%), and stroke on awakening from anesthesia in 2 (3.8%). The death rate of patients treated by endoaortic occlusion was significantly higher compared with all other patients (4.2%, p<0.0001) and with the expected estimate by European System for Cardiac Operative Risk Evaluation (10.5%, p = 0.05). By multivariable analysis, use of endoaortic occlusion was independently associated with in-hospital death (odds ratio = 5.609, 95% confidence interval: 2.684 to 11.719). Although the stroke rate was higher in the endoaortic occlusion group compared with all other patients, the difference was only possibly significant (3.8% versus 0.8%, p = 0.067).'}]

no

The use of endoaortic balloon occlusion for the atherosclerotic ascending aorta is associated with a higher in-hospital death rate and stroke rate compared to other patients, indicating that it may not be safe.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nEstradiol and Antagonist Pretreatment Prior to Microdose Leuprolide in in Vitro Fertilization. Does It Improve IVF Outcomes in Poor Responders as Compared to Oral Contraceptive Pill?\n\nContext:\n-OBJECTIVE: To compare in vitro fertilization (IVF) outcomes in low responders stimulated with microdose leuprolide protocol (ML) following pretreatment with either oral contraceptive pill (OCP) or luteal estradiol (E2) + GnRH antagonist (E2 + antag) for follicular synchronization prior to controlled ovarian hyperstimulation (COH).\n-STUDY DESIGN: This was a retrospective study of 130 women, who were poor responders, undergoing IVF with either OCP/ML or E2+ antag/ML protocols. The main outcome measures were ongoing pregnancy rates, number of oocytes retrieved, and cancellation rate.\n-RESULTS: Both groups were similar in baseline characteristics. There were no significant differences in gonadotropin requirement, cancellation rate, and number of embryos transferred. Ongoing pregnancy rates (40% vs. 15%) were significantly higher in the OCP/ML group. Trends toward greater number of oocytes retrieved (7.7 ± 3.4 vs. 5.9 ± 4.2) and improved implantation rates (20% vs. 12%) were also noted, but these did not reach statistical significance.'}]

no

The study found that poor responders who received estradiol and antagonist pretreatment prior to microdose leuprolide had lower ongoing pregnancy rates compared to those who received oral contraceptive pill pretreatment.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAre opioid dependence and methadone maintenance treatment (MMT) documented in the medical record?\n\nContext:\n-BACKGROUND: Opioid-dependent patients often have co-occurring chronic illnesses requiring medications that interact with methadone. Methadone maintenance treatment (MMT) is typically provided separately from medical care. Hence, coordination of medical care and substance use treatment is important to preserve patient safety.\n-OBJECTIVE: To identify potential safety risks among MMT patients engaged in medical care by evaluating the frequency that opioid dependence and MMT documentation are missing in medical records and characterizing potential medication-methadone interactions.\n-METHODS: Among patients from a methadone clinic who received primary care from an affiliated, but separate, medical center, we reviewed electronic medical records for documentation of methadone, opioid dependence, and potential drug-methadone interactions. The proportions of medical records without opioid dependence and methadone documentation were estimated and potential medication-methadone interactions were identified.\n-RESULTS: Among the study subjects (n = 84), opioid dependence documentation was missing from the medical record in 30% (95% CI, 20%-41%) and MMT documentation was missing from either the last primary care note or the last hospital discharge summary in 11% (95% CI, 5%-19%). Sixty-nine percent of the study subjects had at least 1 medication that potentially interacted with methadone; 19% had 3 or more potentially interacting medications.'}]

yes

Opioid dependence documentation was missing from the medical record in 30% and MMT documentation was missing from either the last primary care note or the last hospital discharge summary in 11%.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan teaching medical students to investigate medication errors change their attitudes towards patient safety?\n\nContext:\n-BACKGROUND: The purpose of this study was to evaluate the impact of a patient-safety curriculum administered during a paediatric clerkship on medical students\' attitudes towards patient safety.\n-METHODS: Medical students viewed an online video introducing them to systems-based analyses of medical errors. Faculty presented an example of a medication administration error and demonstrated use of the Learning From Defects tool to investigate the defect. Student groups identified and then analysed medication errors during their clinical rotation using the Learning From Defects framework to organise and present their findings. Outcomes included patient safety attitudinal changes, as measured by questions derived from the Safety Attitudes Questionnaire.\n-RESULTS: 108 students completed the curriculum between July 2008 and July 2009. All student groups (25 total) identified, analysed and presented patient safety concerns. Curriculum effectiveness was demonstrated by significant changes on questionnaire items related to patient safety attitudes. The majority of students felt that the curriculum was relevant to their clinical rotation and should remain part of the clerkship.'}]

yes

Teaching medical students to investigate medication errors through a patient-safety curriculum can change their attitudes towards patient safety, as demonstrated by significant changes on questionnaire items related to patient safety attitudes.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nHas the prevalence of health care services use increased over the last decade (2001-2009) in elderly people?\n\nContext:\n-OBJECTIVES: (1) To describe the prevalence of general practitioner visits and hospitalization according to sex and age groups; (2) to identify which factors are independently associated with a higher use of health care services among elderly Spanish; and (3) to study the time trends in the prevalence of use of health care services 2001-2009.\n-STUDY DESIGN: Observational study. We analyzed data from the Spanish National Health Surveys conducted in 2001 (n=21,058), 2003 (n=21,650), 2006 (n=29,478) and 2009 (n=22,188). We included responses from adults aged 65 years and older.\n-OUTCOME MEASURES: The main variables were the number of general practitioner visits in the last 4 weeks and hospitalization in the past year. We stratified the adjusted models by the main variables. We analyzed socio-demographic characteristics, health related variables, using multivariate logistic regression models.\n-RESULTS: The total number of subjects was 24,349 (15,041 woman, 9309 men). Women were significantly older than men (P<0.001). Women had higher prevalence of general practitioner visits than men in all surveys. Men had significantly higher prevalence of hospitalizations than women in the years 2001, 2006 and 2009. When we adjusted the hospitalization by possible confounders using logistic regressions, men had a higher probability of being hospitalized than women (OR 1.53, 1.39-1.69). The variables that were significantly associated with a higher use of health care services were lower educational level, worse self-rated health, chronic conditions, polypharmacy, and the level of disability. The number of general practitioner visits among women and men significantly increased from 2001 to 2009 (women: OR 1.43, 1.27-1.61; men: OR 1.71, 1.49-1.97).'}]

yes

The number of general practitioner visits among women and men significantly increased from 2001 to 2009.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes high-dose radiotherapy benefit palliative lung cancer patients?\n\nContext:\n-BACKGROUND AND PURPOSE: The present analysis compares two palliative treatment concepts for lung cancer in terms of overall survival.\n-PATIENTS AND METHODS: Survival data from 207\xa0patients were used in a retrospective analysis. All patients received palliative treatment comprising either 25\xa0Gy applied in 5\xa0fractions or 50\xa0Gy in 20\xa0fractions. A subgroup analysis was performed to compare patients with a good-fair vs. poor overall condition.\n-RESULTS: Median survival times were 21\xa0weeks (range\xa06-26\xa0weeks) for patients treated with 25\xa0Gy in 5\xa0fractions and 23\xa0weeks (range\xa014.5-31.5\xa0weeks) for patients treated with 50\xa0Gy in 20\xa0fractions (95\u2009% confidence interval, CI; p\u2009=\u20090.334). For patients with a good-fair overall condition, median survival times were 30\xa0weeks (21.8-39.2\xa0weeks) for 25\xa0Gy in 5\xa0fractions and 28\xa0weeks (14.2-41.8\xa0weeks) for 50\xa0Gy in 20\xa0fractions (CI 95\u2009%, p\u2009=\u20090.694). In patients with a poor overall condition, these values were 18\xa0weeks (14.5-21.5\xa0weeks) and 21\xa0weeks (13.0-29.0\xa0weeks), respectively (CI 95\u2009%, p\u2009=\u20090.248).'}]

no

The study found that high-dose radiotherapy (50 Gy in 20 fractions) did not significantly improve overall survival compared to low-dose radiotherapy (25 Gy in 5 fractions) in palliative lung cancer patients, with median survival times of 23 weeks and 21 weeks, respectively.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs endothelin-1 an aggravating factor in the development of acute pancreatitis?\n\nContext:\n-OBJECTIVE: We have reported previously that cerulein-induced edematous pancreatitis would transform into hemorrhagic pancreatitis by administration of endothelin-1 in rats. In the present study, we tried to protect rat model from developing into hemorrhagic pancreatitis with BQ123 (an ETA receptor antagonist).\n-METHODS: The rat model was made by 5-hour restraint water-immersion stress and two intraperitoneal injections of cerulein (40 micrograms/kg) at hourly interval. BQ123 (3 or 6 mg/kg) was administered intravenously 30 minutes before and 2 hours after the first cerulein injection.\n-RESULTS: Acute hemorrhagic pancreatitis was induced in all rats treated with cerulin + stress. The score for pancreatic hemorrhage was 2.4 +/- 0.2 in this group. In the rats pretreated with BQ123, the score was reduced to 1.0 +/- 0.0, pancreas wet weight and serum amylase activity were significantly reduced, and histologic alterations in the pancreas lightened, also the local pancreatic blood flow improved without affecting the systemic blood pressure.'}]

yes

Endothelin-1 is an aggravating factor in the development of acute pancreatitis, as it transforms cerulein-induced edematous pancreatitis into hemorrhagic pancreatitis in rats.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nMalnutrition, a new inducer for arterial calcification in hemodialysis patients?\n\nContext:\n-BACKGROUND: Arterial calcification is a significant cardiovascular risk factor in hemodialysis patients. A series of factors are involved in the process of arterial calcification; however, the relationship between malnutrition and arterial calcification is still unclear.\n-METHODS: 68 hemodialysis patients were enrolled in this study. Nutrition status was evaluated using modified quantitative subjective global assessment (MQSGA). Related serum biochemical parameters were measured. And the radial artery samples were collected during the arteriovenous fistula surgeries. Hematoxylin/eosin stain was used to observe the arterial structures while Alizarin red stain to observe calcified depositions and classify calcified degree. The expressions of bone morphogenetic protein 2 (BMP2) and matrix Gla protein (MGP) were detected by immunohistochemistry and western blot methods.\n-RESULTS: 66.18% hemodialysis patients were malnutrition. In hemodialysis patients, the calcified depositions were mainly located in the medial layer of the radial arteries and the expressions of BMP2 and MGP were both increased in the calcified areas. The levels of serum albumin were negatively associated with calcification score and the expressions of BMP2 and MGP. While MQSGA score, serum phosphorus and calcium\u2009×\u2009phosphorus product showed positive relationships with calcification score and the expressions of BMP2 and MGP.'}]

yes

The study found that 66.18% of hemodialysis patients were malnourished, and malnutrition was associated with arterial calcification, as evidenced by the increased expressions of BMP2 and MGP in the calcified areas, and the negative association between serum albumin levels and calcification score.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes glomerular hyperfiltration in pregnancy damage the kidney in women with more parities?\n\nContext:\n-OBJECTIVES: We aimed to investigate the glomerular hyperfiltration due to pregnancy in women with more parities.\n-METHODS: Five hundred women aged 52.57 +/- 8.08 years, without a history of hypertension, diabetes mellitus or complicated pregnancy were involved in the study. They were divided into three groups. Group 1: women with no or one parity (n = 76); group 2: women with two or three parities (n = 333); group 3: women with four or more parities (n = 91). Laboratory parameters and demographical data were compared between the three groups.\n-RESULTS: Mean age, serum urea and serum creatinine were similar between three groups. Patients in group 3 had significantly higher GFR values compared to groups 1 and 2 (109.44 +/- 30.99, 110.76 +/- 30.22 and 121.92 +/- 34.73 mL/min/1.73 m(2) for groups 1, 2 and 3, respectively; P = 0.008 for group 1 vs group 3; P = 0.002 for group 2 vs group 3).'}]

yes

Patients in group 3 had significantly higher GFR values compared to groups 1 and 2, indicating glomerular hyperfiltration in women with more parities.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nSubclavian steal syndrome: can the blood pressure difference between arms predict the severity of steal?\n\nContext:\n-BACKGROUND AND PURPOSE: A side-to-side difference in systolic brachial arterial blood pressure is a common finding in subclavian artery stenosis and is frequently used as a screening tool for subclavian steal syndrome (SSS). It was the goal of this retrospective study to investigate the relationship between different vertebral artery waveform types and the side-to-side difference in systolic blood pressure in patients with sonographically proven SSS.\n-METHODS: The records of 1860 patients from the Neuroultrasound Laboratory between January 2000 and December 2000 were screened for the diagnosis of SSS in the final ultrasound report. In all patients, bilateral brachial arterial blood pressure was measured in a sitting position prior to the ultrasound examination. Vertebral artery waveforms were classified as (1) systolic deceleration, (2) alternating flow, and (3) complete reversal at rest. Blood pressure difference as calculated by normal-side blood pressure minus lesion-side blood pressure was compared with the 3 Doppler waveform types.\n-RESULTS: SSS was found in 51 of 1860 (2.7%) ultrasonography studies of 49 patients (17 men, 32 women; mean age 65.3 +/- 10.5 years). Two patients (4%) had bilateral SSS. In 3 patients (6%), SSS was related to an innominate artery stenosis. Waveform analysis showed a completely reversed flow in 16 (31%), an alternating flow in 24 (47%), and a systolic deceleration in 11 (22%) cases. Systolic blood pressure difference was significantly higher in the complete reversal and alternating groups than in the systolic deceleration group (P<.001).'}]

yes

The study found that the systolic blood pressure difference between arms was significantly higher in patients with subclavian steal syndrome who had a completely reversed flow or alternating flow in the vertebral artery waveform, compared to those with a systolic deceleration waveform.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan the Internet be used to improve sexual health awareness in web-wise young people?\n\nContext:\n-OBJECTIVES: To assess Internet use amongst young people to determine whether it would be a practical way to provide sex education and information.\n-METHODS: Year 10 students (aged 14-15 years) from North Nottinghamshire schools were asked to participate in focus groups to discuss the Internet. A series of predefined questions were directed to the whole group to generate debate. Areas explored included: Internet access and site; frequency and purpose of Internet use; websites visited; ideas for a genitourinary medicine (GUM) website. Responses were recorded by a hand count or as individual verbal responses.\n-RESULTS: Thirteen focus groups were held involving 287 students of approximately equal sex distribution. All had access to Internet facilities at school and 224 (78.0%) had access elsewhere. Access was at least once a week by 178 (62.0%) mostly for e-mail, games, chatlines and homework. No one accessed for health information. One hundred and seventy-nine (62.4%) participants said they would use a GUM website. A \'question line\' where they could e-mail questions to a health care professional was of interest to 202 (70.4%) participants.'}]

yes

The Internet can be used to improve sexual health awareness in web-wise young people, as 62.4% of participants said they would use a Genitourinary Medicine (GUM) website and 70.4% were interested in a 'question line' where they could e-mail questions to a health care professional.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs eligibility for a chemotherapy protocol a good prognostic factor for invasive bladder cancer after radical cystectomy?\n\nContext:\n-PURPOSE: To assess whether eligibility to an adjuvant chemotherapy protocol in itself represents a good prognostic factor after radical cystectomy for bladder cancer.\n-PATIENTS AND METHODS: Between April 1984 and May 1989, our institution entered 35 patients with invasive bladder cancer into the Swiss Group for Clinical and Epidemiological Cancer Research (SAKK) study 09/84. They were randomly assigned to either observation or three postoperative courses of cisplatin monotherapy after cystectomy. This study had a negative result. The outcome of these 35 patients (protocol group) was compared with an age- and tumor-stage-matched cohort (matched group; n = 35) who also underwent cystectomy during the same period, but were not entered into the SAKK study, as well as the remaining 57 patients treated during the study period for the same indication (remaining group).\n-RESULTS: Median overall survival decreased from 76.3 months in the protocol group to 52.1 months in the matched group and to 20.3 months in the remaining group. The respective times of median recurrence-free survival were 67.2, 16.0, and 9.4 months. Tumor progression occurred in 46% of the protocol group compared with 69% in the matched group and 65% in the remaining group (P<.05). Cancer-related death was noted in 40% of the protocol group, 57% in the matched group, and 56% in the remaining group.'}]

yes

Eligibility for a chemotherapy protocol is a good prognostic factor for invasive bladder cancer after radical cystectomy, as patients who were eligible for the protocol had a longer median overall survival and recurrence-free survival, and a lower rate of tumor progression and cancer-related death compared to those who were not eligible.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes a geriatric oncology consultation modify the cancer treatment plan for elderly patients?\n\nContext:\n-BACKGROUND: This study was performed to describe the treatment plan modifications after a geriatric oncology clinic. Assessment of health and functional status and cancer assessment was performed in older cancer patients referred to a cancer center.\n-PATIENTS AND METHODS: Between June 2004 and May 2005, 105 patients 70 years old or older referred to a geriatric oncology consultation at the Institut Curie cancer center were included. Functional status, nutritional status, mood, mobility, comorbidity, medication, social support, and place of residence were assessed. Oncology data and treatment decisions were recorded before and after this consultation. Data were analyzed for a possible correlation between one domain of the assessment and modification of the treatment plan.\n-RESULTS: Patient characteristics included a median age of 79 years and a predominance of women with breast cancer. About one half of patients had an independent functional status. Nearly 15% presented severe undernourishment. Depression was suspected in 53.1% of cases. One third of these patients had>2 chronic diseases, and 74% of patients took>or =3 medications. Of the 93 patients with an initial treatment decision, the treatment plan was modified for 38.7% of cases after this assessment. Only body mass index and the absence of depressive symptoms were associated with a modification of the treatment plan.'}]

yes

The treatment plan was modified for 38.7% of cases after a geriatric oncology consultation.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes left atrial appendage (LAA) occlusion device alter the echocardiography and electrocardiogram parameters in patients with atrial fibrillation?\n\nContext:\n-BACKGROUND: The alterations of echocardiography and electrocardiogram (ECG) in patients received left atrial appendage LAA occlusion therapy are still unclear. The present study was to evaluate the influence of LAA occlusion device on echocardiography and ECG changes in patients with atrial fibrillation (AF).\n-METHODS: Seventy-three patients who had undergone Watchman, LAmbre and Lefort were enrolled in this study. Echocardiography and ECG results at pre- and post-operation were collected. Besides, echocardiography was also performed during follow-up visits at 1, 6 and 12months after discharge.\n-RESULTS: After LAA occlusion, a slight and measureable movement of QRS electric axis was observed in most patients. The significant differences were also observed in heart rate (HR) and the mean-mean QT interval between pre- and post-operation for all patients. There existed no significant difference in echocardiographic parameters between before and after device implantation. However, a larger left atrial (LA) diameter was detected by echocardiography during follow-up visit at 6months when compared with pre-operation parameters. Similarly, aortic root diameter (ARD) was also larger during follow-up at 12months than the baseline dimension in pre-operation.'}]

yes

Yes, left atrial appendage (LAA) occlusion device alters the echocardiography and electrocardiogram parameters in patients with atrial fibrillation, including a slight and measureable movement of QRS electric axis, significant differences in heart rate and mean-mean QT interval, and changes in left atrial and aortic root diameters.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan ki-67 play a role in prediction of breast cancer patients\' response to neoadjuvant chemotherapy?\n\nContext:\n-BACKGROUND: Currently the choice of breast cancer therapy is based on prognostic factors. The proliferation marker Ki-67 is used increasingly to determine the method of therapy. The current study analyses the predictive value of Ki-67 in foreseeing breast cancer patients\' responses to neoadjuvant chemotherapy.\n-METHODS: This study includes patients with invasive breast cancer treated between 2008 and 2013. The clinical response was assessed by correlating Ki-67 to histological examination, mammography, and ultrasonography findings.\n-RESULTS: The average Ki-67 value in our patients collectively (n = 77) is 34.9 ± 24.6%. The average Ki-67 value is the highest with 37.4 ± 24.0% in patients with a pCR. The Ki-67 values do not differ significantly among the 3 groups: pCR versus partial pathological response versus stable disease/progress (P = 0.896). However, Ki-67 values of patients with luminal, Her2 enriched, and basal-like cancers differed significantly from each other. Furthermore, within the group of luminal tumors Ki-67 values of patients with versus without pCR also differed significantly.'}]

yes

The study found that Ki-67 values of patients with versus without pCR differed significantly within the group of luminal tumors, suggesting that Ki-67 may play a role in predicting the response of breast cancer patients to neoadjuvant chemotherapy.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIntravenous administration of metoclopramide by 2 min bolus vs 15 min infusion: does it affect the improvement of headache while reducing the side effects?\n\nContext:\n-OBJECTIVE: To determine the therapeutic effect (alleviation of vascular type headache) and side effects of a slow intravenous metoclopramide infusion over 15 min compared with those effects of a bolus intravenous metoclopramide infusion over 2 min in the treatment of patients with recent onset vascular type headache.\n-MATERIAL AND METHODS: All adults treated with metoclopramide for vascular type headache were eligible for entry into this clinical randomised double blinded trial. This study compared the effects of two different rates of intravenous infusion of metoclopramide over a period of 13 months at a university hospital emergency department. During the trial, side effects and headache scores were recorded at baseline (0 min), and then at 5, 15, 30 and 60 min. Repeated measures analysis of variance was used to compare the medication\'s efficacy and side effects.\n-RESULTS: A total of 120 patients presenting to the emergency department met the inclusion criteria. Of these, 62 patients (51.7%) were given 10 mg metoclopramide as a slow intravenous infusion over 15 min (SIG group) and 58 patients (48.3%) were given 10 mg metoclopramide intravenous bolus infusion over 2 min (BIG group). 17 of the 58 patients in the BIG group (29.3%) and 4 of the 62 patients (6.5%) in the SIG group had akathisia (p = 0.001). There were no significant differences between the BIG and SIG groups in terms of mean headache scores (p = 0.34) and no adverse reactions in the study period. Metoclopramide successfully relieved the headache symptom(s) of patients in both the BIG and SIG groups.'}]

yes

Metoclopramide successfully relieved the headache symptom(s) of patients in both the BIG and SIG groups, with no significant differences in mean headache scores between the two groups, and a lower incidence of akathisia in the SIG group.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs the breast best for children with a family history of atopy?\n\nContext:\n-BACKGROUND: Previous studies reported that breast-feeding protects children against a variety of diseases, but these studies were generally conducted on "high-risk" or hospitalized children. This paper describes the results of our study on the effects of breast-feeding on rate of illness in normal children with a family history of atopy.\n-METHODS: A historic cohort approach of 794 children with a family history of atopy was used to assess the effects of breast-feeding on illness rates. Family history of atopy was based on allergic diseases in family members as registered by the family physician. Illness data from birth onwards were available from the Continuous Morbidity Registration of the Department of Family Medicine. Information on breast-feeding was collected by postal questionnaire. We then compared rates of illness between children with a family history of atopy who were and who were not breast-fed.\n-RESULTS: Breast-feeding was related to lower levels of childhood illness both in the first and the first three years of life. In the first year of life they had fewer episodes of gastroenteritis, lower respiratory tract infections, and digestive tract disorders. Over the next three years of life they had fewer respiratory tract infections and skin infections.'}]

yes

Breast-feeding was related to lower levels of childhood illness both in the first and the first three years of life in children with a family history of atopy.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes escalation of the apical dose change treatment outcome in beta-radiation of posterior choroidal melanomas with 106Ru plaques?\n\nContext:\n-PURPOSE: To show the results of treating posterior uveal melanomas with 106Ru plaque beta-ray radiotherapy and to review and discuss the literature concerning the optimal apical dose prescription (100 vs. 160 Gy).\n-METHODS AND MATERIALS: Forty-eight patients with uveal melanomas (median height 3.85 mm + 1 mm sclera) were treated with ruthenium plaques. The median apical dose was 120 Gy, the median scleral dose 546 Gy.\n-RESULTS: After 5.8 years of follow-up, the overall 5-year survival rate was 90%, the disease specific 5-year survival rate was 92% (3 patients alive with metastasis). Six percent received a second ruthenium application, 10% of the eyes had to be enucleated. Local control was achieved in 90% of the patients with conservative therapy alone. Central or paracentral tumors showed 50% of the pretherapeutic vision after 4 years, and 80% of the vision was preserved in those with peripheral tumors. The main side effects were mostly an uncomplicated retinopathy (30%); macular degeneration or scarring led to poor central vision in 30% of cases.'}]

maybe

The study found that the overall 5-year survival rate was 90% and the disease-specific 5-year survival rate was 92%, with local control achieved in 90% of patients with conservative therapy alone. The study does not explicitly state that escalation of the apical dose changes the treatment outcome, but it does discuss the literature concerning the optimal apical dose prescription (100 vs. 160 Gy).

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes septoplasty change the dimensions of compensatory hypertrophy of the middle turbinate?\n\nContext:\n-OBJECTIVE: To measure the dimensions of compensatory hypertrophy of the middle turbinate in patients with nasal septal deviation, before and after septoplasty.\n-METHODS: The mucosal and bony structures of the middle turbinate and the angle of the septum were measured using radiological analysis before septoplasty and at least one year after septoplasty. All pre- and post-operative measurements of the middle turbinate were compared using the paired sample t-test and Wilcoxon rank sum test.\n-RESULTS: The dimensions of bony and mucosal components of the middle turbinate on concave and convex sides of the septum were not significantly changed by septoplasty. There was a significant negative correlation after septoplasty between the angle of the septum and the middle turbinate total area on the deviated side (p = 0.033).'}]

no

The dimensions of bony and mucosal components of the middle turbinate on concave and convex sides of the septum were not significantly changed by septoplasty.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan patient coaching reduce racial/ethnic disparities in cancer pain control?\n\nContext:\n-PURPOSE: Minority patients with cancer experience worse control of their pain than do their white counterparts. This disparity may, in part, reflect more miscommunication between minority patients and their physicians. Therefore, we examined whether patient coaching could reduce disparities in pain control in a secondary analysis of a randomized controlled trial.\n-METHODS: Sixty-seven English-speaking adult cancer outpatients, including 15 minorities, with moderate pain over the prior 2 weeks were randomly assigned to the experimental (N = 34) or control group (N = 33). Experimental patients received a 20-minute individualized education and coaching session to increase knowledge of pain self-management, to redress personal misconceptions about pain treatment, and to rehearse an individually scripted patient-physician dialog about pain control. The control group received standardized information on controlling pain. Data on average pain (0-10 scale) were collected at enrollment and 2-week follow-up.\n-RESULTS: At enrollment, minority patients had significantly more pain than their white counterparts (6.0 vs 5.0, P = 0.05). At follow-up, minorities in the control group continued to have more pain (6.4 vs 4.7, P = 0.01), whereas in the experimental group, disparities were eliminated (4.0 vs 4.3, P = 0.71). The effect of the intervention on reducing disparities was significant (P = 0.04).'}]

yes

Patient coaching can reduce racial/ethnic disparities in cancer pain control by eliminating the disparities in pain control between minority and white patients.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes prior benign prostate biopsy predict outcome for patients treated with radical perineal prostatectomy?\n\nContext:\n-OBJECTIVES: To determine the effect of prior benign prostate biopsies on the surgical and clinical outcomes of patients treated with radical perineal prostatectomy for prostate cancer.\n-METHODS: A total of 1369 patients with clinically localized prostate cancer underwent radical prostatectomy by a single surgeon between 1991 and 2001. A subset of 203 patients (14.9%), who had undergone at least one prior benign prostate biopsy for a rising prostate-specific antigen and/or abnormal digital rectal examination, constituted our study population. A total of 1115 patients with no prior biopsy represented our control group. After prostatectomy, patients were evaluated at 6-month intervals for biochemical evidence of recurrence, defined as a prostate-specific antigen level of 0.5 ng/mL or greater.\n-RESULTS: Patients with a prior benign biopsy had more favorable pathologic features with more organ-confined (74% versus 64%; P<0.001) and less margin-positive (9.8% versus 18%) disease. Only 24 patients (12%) in the study group (versus 20% in control group; P = 0.01) had eventual evidence of biochemical failure. Kaplan-Meier analyses suggested that patients with prior benign biopsies have improved biochemical disease-free survival, especially for those with more aggressive disease (Gleason sum 7 or greater; P<0.01). Overall, patients in the study group had lower probability (odds ratio 0.57, P<0.001) of biochemical failure compared with those in the control group.'}]

yes

Patients with prior benign prostate biopsy had more favorable pathologic features and improved biochemical disease-free survival, with a lower probability of biochemical failure compared to those without prior biopsy.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes patient position during liver surgery influence the risk of venous air embolism?\n\nContext:\n-BACKGROUND: It is generally believed that positioning of the patient in a head-down tilt (Trendelenberg position) decreases the likelihood of a venous air embolism during liver resection.\n-METHODS: The physiological effect of variation in horizontal attitude on central and hepatic venous pressure was measured in 10 patients during liver surgery. Hemodynamic indices were recorded with the operating table in the horizontal, 20 degrees head-up and 20 degrees head-down positions.\n-RESULTS: There was no demonstrable pressure gradient between the hepatic and central venous levels in any of the positions. The absolute pressures did, however, vary in a predictable way, being highest in the head-down and lowest during head-up tilt. However, on no occasion was a negative intraluminal pressure recorded.'}]

no

The study found that patient position during liver surgery does not influence the risk of venous air embolism, as there was no demonstrable pressure gradient between the hepatic and central venous levels in any of the positions.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDo Indigenous Australians age prematurely?\n\nContext:\n-OBJECTIVE: To assess whether Indigenous Australians age prematurely compared with other Australians, as implied by Australian Government aged care policy, which uses age 50 years and over for population-based planning for Indigenous people compared with 70 years for non-indigenous people.\n-METHODS: Cross-sectional analysis of aged care assessment, hospital and health survey data comparing Indigenous and non-indigenous age-specific prevalence of health conditions. Analysis of life tables for Indigenous and non-indigenous populations comparing life expectancy at different ages.\n-RESULTS: At age 63 for women and age 65 for men, Indigenous people had the same life expectancy as non-indigenous people at age 70. There is no consistent pattern of a 20-year lead in age-specific prevalence of age-associated conditions for Indigenous compared with other Australians. There is high prevalence from middle-age onwards of some conditions, particularly diabetes (type unspecified), but there is little or no lead for others.'}]

no

There is no consistent pattern of a 20-year lead in age-specific prevalence of age-associated conditions for Indigenous compared with other Australians.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAre tuberculosis patients adherent to prescribed treatments in China?\n\nContext:\n-BACKGROUND: Tuberculosis (TB) patients face numerous difficulties adhering to the long-term, rigorous TB treatment regimen. Findings on TB patients\' treatment adherence vary across existing literature and official reports. The present study attempted to determine the actual treatment adherence of new TB patients and to identify factors leading to non-adherence.\n-METHODS: A prospective cohort of 481 newly confirmed TB patients from three counties in western China were enrolled during June to December 2012 and was followed until June 2013. Patients who missed at least one dose of drugs or one follow-up re-examination during the treatment course were deemed as non-adherent. Influencing factors were identified using a logistic regression model.\n-RESULTS: A total of 173 (36.0 %) patients experienced non-adherence and the loss to follow-up cases reached 136 (28.2 %). Only 13.9 % of patients took drugs under direct observation, and 60.5 % of patients were supervised by phone calls. Factor analyses suggested that patients who were observed by family members (OR:5.54, 95 % CI:2.87-10.69) and paying monthly service expenses above 450 RMB (OR:2.08, 95 % CI:1.35-3.19) were more likely to be non-adherent, while supervision by home visit (OR:0.06, 95 % CI:0.01-0.28) and phone calls (OR:0.27, 95 % CI:0.17-0.44) were protective factors.'}]

no

36.0% of patients experienced non-adherence, and 28.2% were lost to follow-up, indicating that a significant portion of tuberculosis patients in China are not adherent to prescribed treatments.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nUltrasound in squamous cell carcinoma of the penis; a useful addition to clinical staging?\n\nContext:\n-OBJECTIVE: As part of the staging procedure in squamous cell carcinoma of the penis, we assessed the role of ultrasound examination, in particular its role in assessing the extent and the invasion into the corpora.\n-METHODS: From 1988 until 1992, all patients referred for primary treatment underwent ultrasound assessment with a 7.5 MHz linear array small parts transducer as part of the clinical workup. All ultrasound images were reviewed by one radiologist, without knowledge of the clinical outcome and were compared with the results obtained at histopathologic examination.\n-RESULTS: In 16 patients the primary tumor and in 1 patient a recurrent cancer after primary therapy were examined. All tumors were identified as hypoechoic lesions. Ultrasound examination in the region of the glans was not able to differentiate between invasion of the subepithelial tissue and invasion into the corpus spongiosum, but absence or presence of invasion into the tunica albuginea of the corpus cavernosum was clearly demonstrated. Accurate measurement by ultrasound of maximum tumor thickness was seen in seven of sixteen examinations.'}]

yes

Ultrasound examination in squamous cell carcinoma of the penis is useful in assessing the invasion into the tunica albuginea of the corpus cavernosum, but it cannot differentiate between invasion of the subepithelial tissue and invasion into the corpus spongiosum.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDo oblique views add value in the diagnosis of spondylolysis in adolescents?\n\nContext:\n-BACKGROUND: Anteroposterior, lateral, and right and left oblique lumbar spine radiographs are often a standard part of the evaluation of children who are clinically suspected of having spondylolysis. Recent concerns regarding radiation exposure and costs have brought the value of oblique radiographs into question. The purpose of the present study was to determine the diagnostic value of oblique views in the diagnosis of spondylolysis.\n-METHODS: Radiographs of fifty adolescents with L5 spondylolysis without spondylolisthesis and fifty controls were retrospectively reviewed. All controls were confirmed not to have spondylolysis on the basis of computed tomographic scanning, magnetic resonance imaging, or bone scanning. Anteroposterior, lateral, and right and left oblique radiographs of the lumbar spine were arranged into two sets of slides: one showing four views (anteroposterior, lateral, right oblique, and left oblique) and one showing two views (anteroposterior and lateral only). The slides were randomly presented to four pediatric spine surgeons for diagnosis, with four-view slides being presented first, followed by two-view slides. The slides for twenty random patients were later reanalyzed in order to calculate of intra-rater agreement. A power analysis demonstrated that this study was adequately powered. Inter-rater and intra-rater agreement were assessed on the basis of the percentage of overall agreement and intraclass correlation coefficients (ICCs). PCXMC software was used to generate effective radiation doses. Study charges were determined from radiology billing data.\n-RESULTS: There was no significant difference in sensitivity and specificity between four-view and two-view radiographs in the diagnosis of spondylolysis. The sensitivity was 0.59 for two-view studies and 0.53 for four-view studies (p = 0.33). The specificity was 0.96 for two-view studies and 0.94 for four-view studies (p = 0.60). Inter-rater agreement, intra-rater agreement, and agreement with gold-standard ICC values were in the moderate range and also demonstrated no significant differences. Percent overall agreement was 78% for four-view studies and 82% for two-view studies. The radiation effective dose was 1.26 mSv for four-view studies and 0.72 mSv for two-view studies (difference, 0.54 mSv). The charge for four-view studies was $145 more than that for two-view studies.'}]

no

There was no significant difference in sensitivity and specificity between four-view and two-view radiographs in the diagnosis of spondylolysis.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAre many colorectal cancers due to missed adenomas?\n\nContext:\n-BACKGROUND: An unknown number of colorectal cancers could be due to missed adenomas during previous endoscopy. Data in the literature are sparse. A large cross-sectional study was done in a prospective database of all patients diagnosed with colorectal cancer.\n-METHODS: All consecutive endoscopies over a period of 15 years, in which colorectal cancer was diagnosed were included. All patients who underwent more than one endoscopy and in whom ultimately cancer was diagnosed were studied separately.\n-RESULTS: Colorectal cancer was diagnosed in 835 patients. Twenty-five patients underwent a previous endoscopy without a cancer diagnosis. These 25 patients were divided into three groups according to the time between the endoscopy in which the cancer was detected and the previous endoscopy. Five out of these 25 patients underwent regular surveillance. Only 11 patients had no argument for regular follow-up. Assuming that these cancers developed from an adenoma than only 11 out of 835 (1.3%) cancers were missed in the adenoma phase. There was no difference in the size of the tumour between the three groups of patients.'}]

no

Only 11 out of 835 (1.3%) colorectal cancers were missed in the adenoma phase, assuming that these cancers developed from an adenoma.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes desflurane alter left ventricular function when used to control surgical stimulation during aortic surgery?\n\nContext:\n-BACKGROUND: Although desflurane is commonly used to control surgically induced hypertension, its effects on left ventricular (LV) function have not been investigated in this clinical situation. The purpose of the present study was to evaluate the LV function response to desflurane, when used to control intraoperative hypertension.\n-METHODS: In 50 patients, scheduled for vascular surgery, anesthesia was induced with sufentanil 0.5 microg/kg, midazolam 0.3 mg/kg and atracurium 0.5 mg/kg. After tracheal intubation, anesthesia was maintained with increments of drugs with controlled ventilation (N2O/O2=60/40%) until the start of surgery. A 5 Mhz transesophageal echocardiography (TEE) probe was inserted after intubation. Pulmonary artery catheter and TEE measurements were obtained after induction (to)(control value), at surgical incision (t1) if it was associated with an increase in systolic arterial pressure (SAP) greater than 140 mmHg (hypertension) and after control of hemodynamic parameters by administration of desflurane (return of systolic arterial pressure to within 20% of the control value) (t2) in a fresh gas flow of 31/ min.\n-RESULTS: Sixteen patients developed hypertension at surgical incision. SAP was controlled by desflurane in all 16 patients. Afterload assessed by systemic vascular resistance index (SVRI), end-systolic wall-stress (ESWS) and left-ventricular stroke work index (LVSWI) increased with incision until the hypertension returned to post-induction values with mean end-tidal concentration of 5.1+/-0.7% desflurane. No change in heart rate, cardiac index, mean pulmonary arterial pressure, stroke volume, end-diastolic and end-systolic cross-sectional areas, fractional area change and left ventricular circumferential fiber shortening was noted when desflurane was added to restore blood pressure.'}]

no

No change in left ventricular function was noted when desflurane was added to restore blood pressure during aortic surgery.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nDoes gestational age misclassification explain the difference in birthweights for Australian aborigines and whites?\n\nContext:\n-BACKGROUND: After 34 weeks gestation, summary measures of location for birthweight (e.g means and centiles) increase more slowly for Australian Aborigines than for whites. A similar pattern has been observed for blacks in the US. This study tests whether the reported pattern is due to differential misclassification of gestational age.\n-METHODS: Simulation was used to measure the potential effect of differential misclassification of gestational age. Reported gestational age data were obtained from Queensland Perinatal Data Collection (QPDC). Estimates of the true distributions of gestational age were obtained by assuming various (plausible) types of misclassification and applying these to the reported distributions. Previous studies and data from the QPDC were used to help specify the birthweight distributions used in the simulations.\n-RESULTS: At full term, the parameters of the birthweight distributions were robust to gestational age misclassification. At preterm, the 10th centiles were robust to misclassification. In contrast, the 90th centiles were sensitive to even minor misclassification. Extreme types of misclassification were required to remove the divergence in median birthweights for Aborigines and whites.'}]

no

Gestational age misclassification does not fully explain the difference in birthweights for Australian Aborigines and whites, as extreme types of misclassification were required to remove the divergence in median birthweights.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs there any interest to perform ultrasonography in boys with undescended testis?\n\nContext:\n-OBJECTIVE: To evaluate the accuracy of ultrasonographic examination in boys with an undescended testis.\n-MATERIAL AND METHODS: All patients who were referred to the paediatric surgeon after detection of an undescended testis were evaluated prospectively between November 2001 and November 2004. Among these 377 patients, 87 were referred with an ultrasonogram previously prescribed by the referring primary physician. The results of the ultrasonogram were compared to the results of the clinical examination of the paediatric surgeon and, in cases of no palpable testis, to the surgical findings.\n-RESULTS: Ultrasonography did not detect the retractile testes. Ultrasonography detected 67% of the palpable undescended testes. In cases of no palpable testis, the ultrasonographic examination missed the abdominal testes and sometimes other structures were falsely interpreted as a testis.'}]

yes

Yes, there is interest to perform ultrasonography in boys with undescended testis, as it was evaluated for its accuracy in detecting undescended testes.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nIs peak concentration needed in therapeutic drug monitoring of vancomycin?\n\nContext:\n-BACKGROUND: We analyzed the pharmacokinetic-pharmacodynamic relationship of vancomycin to determine the drug exposure parameters that correlate with the efficacy and nephrotoxicity of vancomycin in patients with methicillin-resistant Staphylococcus aureus pneumonia and evaluated the need to use peak concentration in therapeutic drug monitoring (TDM).\n-METHODS: Serum drug concentrations of 31 hospitalized patients treated with vancomycin for methicillin-resistant S. aureus pneumonia were collected.\n-RESULTS: Significant differences in trough concentration (Cmin)/minimum inhibitory concentration (MIC) and area under the serum concentration-time curve (AUC0-24)/MIC were observed between the response and non-response groups. Significant differences in Cmin and AUC0-24 were observed between the nephrotoxicity and non-nephrotoxicity groups. Receiver operating characteristic curves revealed high predictive values of Cmin/MIC and AUC0-24/MIC for efficacy and of Cmin and AUC0-24 for safety of vancomycin.'}]

no

The study found that significant differences in trough concentration (Cmin)/minimum inhibitory concentration (MIC) and area under the serum concentration-time curve (AUC0-24)/MIC were observed between the response and non-response groups, and between the nephrotoxicity and non-nephrotoxicity groups, indicating that peak concentration is not solely needed in therapeutic drug monitoring of vancomycin.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nCan autologous platelet-rich plasma gel enhance healing after surgical extraction of mandibular third molars?\n\nContext:\n-PURPOSE: This investigation assesses the effect of platelet-rich plasma (PRP) gel on postoperative pain, swelling, and trismus as well as healing and bone regeneration potential on mandibular third molar extraction sockets.\n-PATIENTS AND METHODS: A prospective randomized comparative clinical study was undertaken over a 2-year period. Patients requiring surgical extraction of a single impacted third molar and who fell within the inclusion criteria and indicated willingness to return for recall visits were recruited. The predictor variable was application of PRP gel to the socket of the third molar in the test group, whereas the control group had no PRP. The outcome variables were pain, swelling, and maximum mouth opening, which were measured using a 10-point visual analog scale, tape, and millimeter caliper, respectively. Socket healing was assessed radiographically by allocating scores for lamina dura, overall density, and trabecular pattern. Quantitative data were presented as mean. Mann-Whitney test was used to compare means between groups for continuous variables, whereas Fischer exact test was used for categorical variables. Statistical significance was inferred at P<.05.\n-RESULTS: Sixty patients aged 19 to 35 years (mean: 24.7 ± 3.6 years) were divided into both test and control groups of 30 patients each. The mean postoperative pain score (visual analog scale) was lower for the PRP group at all time points and this was statistically significant (P<.05). Although the figures for swelling and interincisal mouth opening were lower in the test group, this difference was not statistically significant. Similarly, the scores for lamina dura, trabecular pattern, and bone density were better among patients in the PRP group. This difference was also not statistically significant.'}]

yes

The application of autologous platelet-rich plasma gel to the socket of the third molar in the test group resulted in lower mean postoperative pain scores, which were statistically significant, and better scores for lamina dura, trabecular pattern, and bone density, although these differences were not statistically significant.

[{'role': 'system', 'content': 'You will answer the given Question based on given Context. The context is the abstract of medical paper'}, {'role': 'user', 'content': 'Given Question and Context as the INPUT, please answer the question following the Instruction\n\n# Instruction:\n1. Please read and understand carefully each point in the Context. This will be your only knowledge when answering question.\n2. Read the Question and answer it ONLY using the information in Context\n3. Deliver two types of answers from given Question, Long-Answer and Short-Answer. Long-Answer contains straight forward answer, then based on the Long-Answer, give Short-answer that contains "yes", "maybe", or "no".\n\n# Important Note\nReturn the answers in following JSON format\n{\n "Long-Answer": <Generated Long-Answer>,\n "Short-Answer": <Generated Short-Answer>\n}\n\nDo not add additional explanation beside the JSON output!\n\nINPUT:\nQuestion:\nAre sugars-free medicines more erosive than sugars-containing medicines?\n\nContext:\n-OBJECTIVE: The reduced use of sugars-containing (SC) liquid medicines has increased the use of other dose forms, potentially resulting in more widespread dental effects, including tooth wear. The aim of this study was to assess the erosive potential of 97 paediatric medicines in vitro.\n-METHODS: The study took the form of in vitro measurement of endogenous pH and titratable acidity (mmol). Endogenous pH was measured using a pH meter, followed by titration to pH 7.0 with 0.1-M NaOH.\n-RESULTS: Overall, 55 (57%) formulations had an endogenous pH of<5.5. The mean (+/- SD) endogenous pH and titratable acidity for 41 SC formulations were 5.26 +/- 1.30 and 0.139 +/- 0.133 mmol, respectively; for 56 sugars-free (SF) formulations, these figures were 5.73 +/- 1.53 and 0.413 +/- 1.50 mmol (P>0.05). Compared with their SC bioequivalents, eight SF medicines showed no significant differences for pH or titratable acidity, while 15 higher-strength medicines showed lower pH (P = 0.035) and greater titratable acidity (P = 0.016) than their lower-strength equivalents. Chewable and dispersible tablets (P<0.001), gastrointestinal medicines (P = 0.002) and antibiotics (P = 0.007) were significant predictors of higher pH. In contrast, effervescent tablets (P<0.001), and nutrition and blood preparations (P = 0.021) were significant predictors of higher titratable acidity.'}]

no

The study found that 56 sugars-free (SF) formulations had a mean endogenous pH of 5.73 +/- 1.53 and titratable acidity of 0.413 +/- 1.50 mmol, which is not significantly different from the 41 sugars-containing (SC) formulations with a mean endogenous pH of 5.26 +/- 1.30 and titratable acidity of 0.139 +/- 0.133 mmol (P>0.05).