response
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{
"REASONING": [
"The DOCUMENT states that 'CHIKV has been isolated into three genotypes based on phylogenetic studies.'",
"It further specifies that 'These genotypes, based on the gene sequences of an Envelope protein (E1), are Asian, East/Central/ South African, and West African.'",
"The ANSWER correctly identifies the genotypes as Asian, East/Central/ South African, and West African.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,214 |
{
"REASONING": [
"The QUESTION asks for the third most prevalent cancer in females in the United States.",
"The DOCUMENT states: 'colorectal cancer is the second and third most prevalent cancer among males and females in the United States, respectively.'",
"The ANSWER provided is 'colorectal cancer'.",
"The ANSWER directly matches the information provided in the DOCUMENT without adding or contradicting any details."
],
"SCORE": "PASS"
} | PASS | 422 |
{
"REASONING": [
"The DOCUMENT states that glycyrrhizin is a triterpene saponine.",
"The ANSWER correctly identifies glycyrrhizin as a triterpene saponine.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 383 |
{
"REASONING": [
"The DOCUMENT states that 'Dysregulation of the antibody response can lead to an autoimmune disease, malignancy, or enhanced infection.'",
"The ANSWER repeats this information verbatim without adding or contradicting any details from the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 147 |
{
"REASONING": [
"The QUESTION asks for the Insomnia Severity Index scores.",
"The DOCUMENT provides the Insomnia Severity Index scores as follows: 'median [IQR] Insomnia Severity Index scores among frontline vs second-line workers: 6.0 [2.0-11.0] vs 4.0 [1.0-8.0]; P < .001'.",
"The ANSWER states: 'among frontline vs second-line workers: 6.0 [2.0-11.0] vs 5.0 [1.0-8.0]; P < .001'.",
"The ANSWER correctly identifies the score for frontline workers as 6.0 [2.0-11.0].",
"The ANSWER incorrectly identifies the score for second-line workers as 5.0 [1.0-8.0] instead of the correct 4.0 [1.0-8.0] as provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 464 |
{
"REASONING": [
"The QUESTION asks for the G+C content.",
"The DOCUMENT states: 'The G + C content was 38%'.",
"The ANSWER provided is '36%'.",
"The ANSWER contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 1,934 |
{
"REASONING": [
"The DOCUMENT states that currently, ELISA and IFA are the clinically-available methods for the detection of encephalitis viral antigens.",
"The ANSWER correctly lists ELISA and IFA as the current clinically-available methods.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 42 |
{
"REASONING": [
"The DOCUMENT discusses the presence of resistance-associated substitutions (RASs) in HCV, which can affect the efficacy of direct-acting antiviral agents (DAAs).",
"It mentions that both baseline (preexisting) and emergent (developing during treatment) RASs can compromise treatment outcomes.",
"The ANSWER states 'baseline and emergent resistance mutations' as key factors preventing the elimination of HCV infection in some patients.",
"This ANSWER is consistent with the information provided in the DOCUMENT, which highlights the role of both baseline and emergent RASs in treatment failure."
],
"SCORE": "PASS"
} | FAIL | 361 |
{
"REASONING": [
"The DOCUMENT states that 'The SARS-CoV-2 virus is a betacoronavirus, like MERS-CoV and SARS-CoV.'",
"The ANSWER provided is 'betacoronavirus'.",
"The ANSWER directly matches the information given in the DOCUMENT without adding or contradicting any details."
],
"SCORE": "PASS"
} | PASS | 1,303 |
{
"REASONING": [
"The DOCUMENT states that mutational pressure is the most important determinant in RHDV with high codon bias.",
"The DOCUMENT also mentions that codon usage bias in human RNA viruses is related to mutational pressure, G +C content, the segmented nature of the genome, and the route of transmission of the virus.",
"The DOCUMENT does not explicitly state that natural selection is a main factor for codon usage variation in RHDV.",
"The ANSWER includes 'natural selection' as a factor, which is not supported by the DOCUMENT for RHDV specifically."
],
"SCORE": "FAIL"
} | FAIL | 173 |
{
"REASONING": [
"The DOCUMENT states that Universal primer-PCR is a virus discovery technique that uses universal primers designed on conserved parts of a specific viral family.",
"The purpose of this technique is to detect novel variants of this viral family.",
"The ANSWER 'detect novel variants' is directly aligned with the information provided in the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 821 |
{
"REASONING": [
"The QUESTION asks for the nucleoside analog that is the focus of the current study.",
"The DOCUMENT repeatedly mentions gemcitabine as the nucleoside analog being studied.",
"The DOCUMENT does not mention 'gemcitabine hydrochloride' specifically; it only refers to 'gemcitabine'.",
"The ANSWER 'gemcitabine hydrochloride' introduces a specific form of gemcitabine that is not mentioned in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 165 |
{
"REASONING": [
"The provided ANSWER does not address the QUESTION, which asks about what the author anticipates that continued efforts will lead to.",
"The ANSWER only mentions 'Another mRNA under post-transcriptional regulation by Regnase-1 and Roquin,' which is a fragment and does not provide a complete or relevant response to the QUESTION.",
"The DOCUMENT contains specific anticipations by the author, such as new methods of regaining control over inflammation in autoimmunity, selectively enhancing immunity in immunotherapy, and modulating RNA synthesis and virus replication during infection.",
"The provided ANSWER does not reflect any of these anticipations or any other relevant information from the DOCUMENT."
],
"SCORE": "FAIL"
} | PASS | 1,833 |
{
"REASONING": [
"The provided answer states that SARS-CoV and MERS-CoV may cause severe lower respiratory tract infection with acute respiratory distress syndrome and extrapulmonary manifestations, such as diarrhea, lymphopenia, deranged liver and renal function tests, and multiorgan dysfunction syndrome.",
"The answer also mentions the mortality rates of ∼15% and ∼35% for SARS-CoV and MERS-CoV, respectively.",
"Upon reviewing the DOCUMENT, it is clear that the information about the severe lower respiratory tract infection, acute respiratory distress syndrome, and extrapulmonary manifestations is present.",
"However, the DOCUMENT states the mortality rates as ∼10% for SARS-CoV and ∼35% for MERS-CoV, not ∼15% for SARS-CoV as mentioned in the ANSWER.",
"Therefore, the ANSWER contains a discrepancy regarding the mortality rate of SARS-CoV."
],
"SCORE": "FAIL"
} | FAIL | 1,924 |
{
"REASONING": [
"The DOCUMENT states that the orf1ab gene of the Bovine coronavirus (BCoV) is 20kb nucleotides in length.",
"The ANSWER provided is '20kb', which matches the information given in the DOCUMENT.",
"There is no additional or contradictory information in the ANSWER compared to the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 25 |
{
"REASONING": [
"The DOCUMENT states that CXRs revealed multiple bilateral lobar or segment consolidation in the lungs of all five patients.",
"The ANSWER incorrectly mentions 'unilateral' instead of 'bilateral'.",
"The DOCUMENT also mentions that radiographic lesions progressed rapidly after ICU admission, which is correctly reflected in the ANSWER."
],
"SCORE": "FAIL"
} | FAIL | 397 |
{
"REASONING": [
"The DOCUMENT states that 'Since 2011, influenza vaccination campaign in Reunion Island starts in April.'",
"The ANSWER provided is 'April'.",
"The ANSWER does not contradict the DOCUMENT and does not offer new information beyond the context provided in the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 591 |
{
"REASONING": [
"The DOCUMENT states that MERS-CoV appears to have a mortality rate of 35-50% of diagnosed infections.",
"The ANSWER provided is '35-50%', which directly matches the information given in the DOCUMENT.",
"There is no additional information or contradiction in the ANSWER compared to the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 906 |
{
"REASONING": [
"The DOCUMENT clearly states that the World Health Organization declared the Ebola epidemic in West Africa as a Public Health Emergency of International Concern on 8 August 2014.",
"The ANSWER provided is 11 August 2014, which is incorrect according to the DOCUMENT.",
"The ANSWER contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 1,474 |
{
"REASONING": [
"The DOCUMENT mentions a rumour that SARS-CoV-2 has HIV sequence in it and was thus likely generated in the laboratory.",
"The ANSWER incorrectly states that the rumour claimed SARS-CoV-2 has Ebola sequence in it.",
"There is no mention of Ebola in the DOCUMENT.",
"The ANSWER contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 632 |
{
"REASONING": [
"The DOCUMENT does not mention 'glutathione peroxidase' as a parameter used to measure antioxidant levels.",
"The DOCUMENT specifically mentions 'total antioxidant status (TAS)' as the parameter used to measure antioxidant levels.",
"The ANSWER 'glutathione peroxidase' introduces new information not found in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 198 |
{
"REASONING": [
"The provided answer states that vaccines are a minor component of CHIKV disease control and that research in this area is not highly encouraged.",
"The document, however, emphasizes the importance of vaccines in combating CHIKV. It mentions that vaccines are a critical component of CHIKV disease control and that research in this area is highly encouraged.",
"The document discusses various vaccine strategies, including DNA vaccines, and highlights their potential in controlling CHIKV.",
"The document also underscores the need for further investigation and development of vaccines to prevent the morbidity and mortality associated with CHIKV."
],
"SCORE": "FAIL"
} | FAIL | 1,252 |
{
"REASONING": [
"The DOCUMENT states that 'Pneumonia remains the leading cause of death in children outside the neonatal period.'",
"The ANSWER correctly states that 'Pneumonia remains the leading cause of death in children outside the neonatal period.'",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 103 |
{
"REASONING": [
"The DOCUMENT states that transmission of respiratory viruses generally happens through large respiratory droplets.",
"It also mentions that some respiratory viruses can spread through fine particle aerosols.",
"The ANSWER, 'through fine particle aerosols,' is directly supported by the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,542 |
{
"REASONING": [
"The DOCUMENT mentions that the numbers of infected persons and verified deaths are likely underestimates due to limited information available regarding incubation time, transmissibility, and virus origin.",
"The ANSWER correctly identifies these three factors (incubation time, transmissibility, and virus origin) as reasons why the spread of COVID-19 might be underestimated.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,963 |
{
"REASONING": [
"The DOCUMENT states: 'The patient was instructed to breath orally at tidal volumes into a mouthpiece attached to a condenser for 10 minutes.'",
"The ANSWER provided is '10 minutes'.",
"The ANSWER directly matches the information given in the DOCUMENT without adding or contradicting any details."
],
"SCORE": "PASS"
} | PASS | 98 |
{
"REASONING": [
"The DOCUMENT states that the FPASSA-ANFIS model showed better performance compared to several existing models in terms of Mean Absolute Percentage Error (MAPE), Root Mean Squared Relative Error (RMSRE), coefficient of determination (R2), and computing time.",
"The DOCUMENT also mentions that the outcomes of testing the proposed model using two different datasets of weekly influenza confirmed cases in the USA and China showed good performances.",
"The ANSWER, 'showed poor performances,' directly contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 509 |
{
"REASONING": [
"The DOCUMENT states: 'The reverse transcription reaction mixture contained 5 μl of the RNA template...'",
"The provided ANSWER states: '4 μl'",
"The ANSWER contradicts the DOCUMENT, which clearly specifies 5 μl of the RNA template."
],
"SCORE": "FAIL"
} | FAIL | 358 |
{
"REASONING": [
"The DOCUMENT suggests that the next Director-General should be a proven leader and advocate, perhaps from a low-income or middle-income country.",
"There is no mention in the DOCUMENT that the next Director-General should come from a high-income country.",
"The ANSWER contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 181 |
{
"REASONING": [
"The DOCUMENT describes RANBP2 as a nuclear pore protein, not a cytoplasmic pore protein.",
"The DOCUMENT states that RANBP2 has numerous roles in the cell cycle and is associated with microtubules and mitochondria, suggesting roles in intracellular protein trafficking or energy maintenance and homeostasis of neuronal cells.",
"The provided ANSWER 'cytoplasmic pore protein' is not accurate according to the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 201 |
{
"REASONING": [
"The DOCUMENT states that '199 symptomatic cases have been diagnosed on board as of 24 February'.",
"The ANSWER provided is '199', which matches the number of symptomatic cases confirmed on the Diamond Princess cruise ship as per the DOCUMENT.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,505 |
{
"REASONING": [
"The QUESTION asks about intestinal factors that may reduce the effectiveness of orally-administered immunizations.",
"The DOCUMENT mentions several challenges to oral immunization, specifically citing 'physical, chemical, and biological barriers when delivering antigens to the gastrointestinal (GI) tract (such as gastric acids, pepsin, and trypsin in the GI tract)'.",
"The ANSWER lists 'gastric acids, pepsin, and trypsin', which are directly mentioned in the DOCUMENT as barriers to oral immunization.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 756 |
{
"REASONING": [
"The DOCUMENT mentions that 'Transmission of respiratory viruses generally happens through large respiratory droplets, but some respiratory viruses can spread through fine particle aerosols, and indirect transmission via fomites can also play a role.'",
"The DOCUMENT also states, 'Coronaviruses can also infect the human gastrointestinal tract, and faecal-oral transmission might also play a role in this instance.'",
"The ANSWER 'airborne transmission' is consistent with the DOCUMENT's mention of 'fine particle aerosols' as a mode of transmission."
],
"SCORE": "PASS"
} | FAIL | 1,544 |
{
"REASONING": [
"The DOCUMENT states that nurses, women, frontline health care workers, and those working in Wuhan reported more severe degrees of all measurements of mental health symptoms.",
"The ANSWER incorrectly mentions that physicians, men, those outside Wuhan, and second-line health care workers reported experiencing psychological burden.",
"This directly contradicts the findings in the DOCUMENT, which highlight the opposite groups as experiencing more severe psychological symptoms."
],
"SCORE": "FAIL"
} | FAIL | 468 |
{
"REASONING": [
"The DOCUMENT states that determining the spectrum of clinical manifestations of 2019-nCoV infections is perhaps the most urgent research priority.",
"The reason given in the DOCUMENT is that it determines the strength of public health response required.",
"The ANSWER provided matches this reasoning exactly and does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,548 |
{
"REASONING": [
"The DOCUMENT explicitly states, 'We do not have a universal vaccine to prevent all influenza virus infections.' This directly contradicts the ANSWER's claim that 'We have a universal vaccine to prevent all influenza virus infections.'",
"The DOCUMENT does mention that 'we can make effective vaccines to a specific influenza virus strain in a short time,' which is correctly reflected in the ANSWER.",
"Since the ANSWER includes the incorrect statement about having a universal vaccine, it is not fully faithful to the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 2,008 |
{
"REASONING": [
"The DOCUMENT states that the ECDC and the WHO Regional Office for Europe asked countries to complete a WHO standard COVID-19 case report form for all confirmed and probable cases according to WHO criteria.",
"The ANSWER only mentions 'confirmed cases' and omits 'probable cases'.",
"The omission of 'probable cases' means the ANSWER is not fully faithful to the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 1,767 |
{
"REASONING": [
"The DOCUMENT states that three of the five patients had relatively low T-cell counts when admitted.",
"The DOCUMENT suggests that these three patients may have been relatively immunocompromised.",
"The DOCUMENT concludes that a lower T-cell count may be a risk factor for HAdV-55 infection in young adults."
],
"SCORE": "PASS"
} | PASS | 404 |
{
"REASONING": [
"The DOCUMENT describes the development of a Bats-Hosts-Reservoir-People (BHRP) transmission network model.",
"The ANSWER correctly identifies the BHRP model as the method developed in the study.",
"The DOCUMENT also mentions that the BHRP model was simplified to a Reservoir-People (RP) transmission network model for practical purposes.",
"The ANSWER does not contradict any information provided in the DOCUMENT.",
"The ANSWER does not introduce any new information beyond what is provided in the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,479 |
{
"REASONING": [
"The DOCUMENT states that the event was reported to the World Health Organization (WHO) on 31 December 2019.",
"The ANSWER provided is '31 December', which matches the date mentioned in the DOCUMENT.",
"There is no additional information or contradiction in the ANSWER compared to the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 768 |
{
"REASONING": [
"The DOCUMENT states that dendritic cells (DCs) are the most important professional antigen-presenting cells.",
"The DOCUMENT also mentions that DCs can effectively regulate antibody titers and naturally exist in the gut-associated lymphoid tissue (GALT).",
"The provided ANSWER, 'antigen-presenting cells,' is consistent with the information in the DOCUMENT.",
"The ANSWER does not introduce new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 758 |
{
"REASONING": [
"The DOCUMENT states that 'Fe also plays an important role in pathogenesis of bacterial infections as bacteria utilize Fe for survival, growth and proliferation.'",
"The ANSWER states that 'bacteria utilize Fe for survival, growth and reproduction.'",
"The terms 'proliferation' and 'reproduction' are synonymous in this context, both referring to the increase in number of bacteria.",
"The ANSWER does not introduce new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | FAIL | 194 |
{
"REASONING": [
"The QUESTION asks about what confers a high risk of gender-based violence.",
"The DOCUMENT states that 'latrines in crisis settings are often shared and distant from residential shelters, conferring a high risk of gender-based violence.'",
"The ANSWER provided is 'latrines in crisis settings are often shared and distant from residential shelters,' which is a direct excerpt from the DOCUMENT.",
"The ANSWER does not include the part about conferring a high risk of gender-based violence, but it does not contradict the DOCUMENT either.",
"The ANSWER is faithful to the DOCUMENT as it accurately reflects the content provided, even though it is incomplete in addressing the QUESTION fully."
],
"SCORE": "PASS"
} | PASS | 1,997 |
{
"REASONING": [
"The DOCUMENT states that in Asia, the transmission of Chikungunya virus (CHIKV) occurs in an urban cycle.",
"It specifies that the mosquito spreads the disease from an infected human to an uninfected human.",
"The DOCUMENT also mentions that this transmission pattern follows an epidemiological pattern similar to dengue fever.",
"The ANSWER accurately reflects this information without adding or contradicting any details from the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,208 |
{
"REASONING": [
"The DOCUMENT states that the first death in France was reported on 15 February.",
"The ANSWER states that the first death in France was on 16 February.",
"The ANSWER contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 1,771 |
{
"REASONING": [
"The DOCUMENT explicitly states that a high concentration of viral RNA in anal swabs suggests the digestive tract might be one extrapulmonary site for virus replication.",
"The DOCUMENT provides evidence that the virus was detected in higher concentrations in anal swabs compared to blood, indicating possible replication in the digestive tract.",
"The ANSWER contradicts the DOCUMENT by stating that the digestive tract might not be an extrapulmonary site for virus replication, which is the opposite of what the DOCUMENT suggests."
],
"SCORE": "FAIL"
} | FAIL | 1,471 |
{
"REASONING": [
"The DOCUMENT states that MALAT1 is a long non-coding RNA which is over-expressed in many human oncogenic tissues and regulates cell cycle and survival.",
"The ANSWER correctly states that MALAT1 regulates cell cycle and survival.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 248 |
{
"REASONING": [
"The DOCUMENT explicitly states that the mean incubation period was 5.2 days with a 95% confidence interval of 4.1-7.0.",
"The ANSWER provided is '5.2 days (95% confidence interval [CI]: 4.1-7.0)', which directly matches the information given in the DOCUMENT.",
"There is no additional information or contradiction in the ANSWER compared to the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,489 |
{
"REASONING": [
"The DOCUMENT explicitly states that the current strategy for the detection of viral RNA in oral swabs used for 2019-nCoV diagnosis is not perfect.",
"The DOCUMENT provides evidence that the virus can be present in anal swabs or blood of patients even when oral swabs are negative.",
"The ANSWER contradicts the DOCUMENT by claiming that the detection strategy using oral swabs is perfect and that the virus is not present in anal swabs or blood when oral swabs are negative."
],
"SCORE": "FAIL"
} | FAIL | 1,747 |
{
"REASONING": [
"The QUESTION asks for the number of patients with acute RTIs.",
"The DOCUMENT states that there were 267 episodes of acute RTIs from 263 patients.",
"The ANSWER provided is 263, which refers to the number of patients, not the number of episodes.",
"The ANSWER is faithful to the DOCUMENT as it correctly identifies the number of patients with acute RTIs."
],
"SCORE": "PASS"
} | PASS | 233 |
{
"REASONING": [
"The DOCUMENT states that 'a lower T-cell count may be a risk factor for HAdV-55 infection in young adults.'",
"The ANSWER claims that 'a higher T-cell count may be a risk factor for HAdV-55 infection in young adults,' which directly contradicts the information provided in the DOCUMENT.",
"The DOCUMENT provides evidence that lower T-cell counts were observed in patients with severe HAdV-55 infection, suggesting that lower, not higher, T-cell counts are associated with increased risk."
],
"SCORE": "FAIL"
} | FAIL | 404 |
{
"REASONING": [
"The provided answer states that hunting for the animal source of 2019-nCoV and its more ancestral virus is important for understanding the origin and evolution of this novel lineage B betacoronavirus.",
"The DOCUMENT explicitly mentions that learning from the roles of civet in SARS and camel in MERS, hunting for the animal source of 2019-nCoV and its more ancestral virus would be important for understanding the origin and evolution of this novel lineage B betacoronavirus.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,916 |
{
"REASONING": [
"The DOCUMENT states that the aim of the current study was to assess the overall in vitro bactericidal activity of nine newly synthesized diamides.",
"The ANSWER correctly identifies the purpose of the research as assessing the overall in vitro bactericidal activity of nine newly synthesized diamides.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 350 |
{
"REASONING": [
"The DOCUMENT states that 'children under 6 months of age accounted for 44% of HMPV positive cases' in Kilifi coastal Kenya between January 2007 to December 2011.",
"The ANSWER provided is 'children under 1 year of age'.",
"While the DOCUMENT does mention that 74% of HMPV positive cases were children under 1 year, the specific 44% figure is attributed to children under 6 months of age.",
"The ANSWER is not faithful to the DOCUMENT as it does not accurately reflect the specific age group that accounted for 44% of the cases."
],
"SCORE": "FAIL"
} | FAIL | 223 |
{
"REASONING": [
"The DOCUMENT states that 'Pertussis is a cyclical disease, thought to peak every 2 to 4 years.'",
"The ANSWER 'every 2 to 4 years' directly reflects this information from the DOCUMENT.",
"There is no additional information or contradiction in the ANSWER compared to the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 283 |
{
"REASONING": [
"The DOCUMENT states that the study analyzed a 2019-nCoV complete genome from a patient in a familial cluster and compared it with the genomes of related βCoVs, not αCoVs.",
"The ANSWER incorrectly mentions αCoVs instead of βCoVs.",
"The rest of the ANSWER correctly mentions the purpose of providing insights into the potential source and control strategies."
],
"SCORE": "FAIL"
} | FAIL | 1,926 |
{
"REASONING": [
"The DOCUMENT states that SSA is employed to improve FPA to avoid its drawbacks, specifically getting trapped at the local optima.",
"The ANSWER correctly states that SSA is used to improve FPA to avoid its drawbacks, which aligns with the information provided in the DOCUMENT.",
"There is no additional or contradictory information in the ANSWER compared to the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 503 |
{
"REASONING": [
"The provided answer states that 'a recent paper demonstrates that topoisomerase I can protect against inflammation-induced death from a variety of viral infections including IAV.'",
"The DOCUMENT mentions that 'A recent paper demonstrates that topoisomerase I can protect against inflammation-induced death from a variety of viral infections including IAV [70].'",
"The answer does not introduce any new information beyond what is provided in the DOCUMENT.",
"The answer does not contradict any information provided in the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 923 |
{
"REASONING": [
"The DOCUMENT states that 'In patients with high initial viral titers there is a poor prognosis.'",
"The ANSWER claims 'In patients with low initial viral titers there is a poor prognosis.'",
"The ANSWER directly contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 917 |
{
"REASONING": [
"The DOCUMENT states that hepcidin plays an active role in the regulation of Fe release from macrophages and in the control of excessive Fe absorption from the duodenum.",
"The ANSWER incorrectly mentions the jejunum instead of the duodenum.",
"This discrepancy means the ANSWER is not faithful to the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 195 |
{
"REASONING": [
"The QUESTION asks for the median time until death in MERS-COV.",
"The DOCUMENT states: 'the median time until death is 11-13 days (range 5-27 days) among severely ill patients'.",
"The ANSWER provided is: 'median time until death is 11-13 days (range 5-27 days) among severely ill patients'.",
"The ANSWER directly matches the information provided in the DOCUMENT without adding or contradicting any details."
],
"SCORE": "PASS"
} | PASS | 160 |
{
"REASONING": [
"The DOCUMENT states that a stratified multi-stage random sampling was used to select the clusters.",
"The ANSWER correctly identifies the method as 'stratified multi stage random sampling'.",
"The ANSWER does not contradict any information provided in the DOCUMENT.",
"The ANSWER does not offer new information beyond the context provided in the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 58 |
{
"REASONING": [
"The DOCUMENT states that the detected case fatality rate for H7N9 avian influenza A virus was 32.14% (45/140, including one case from Taiwan and one case from Hong Kong).",
"The ANSWER correctly reflects this information without adding or contradicting any details from the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 2,012 |
{
"REASONING": [
"The DOCUMENT states that people with serious chronic medical conditions like heart disease, diabetes, and lung disease are at higher risk of developing serious COVID-19 illness.",
"The ANSWER correctly includes heart disease and diabetes, which are mentioned in the DOCUMENT.",
"The ANSWER incorrectly includes kidney disease, which is not mentioned in the DOCUMENT.",
"The DOCUMENT mentions lung disease as a condition that increases the risk of severe illness, but this is omitted in the ANSWER."
],
"SCORE": "FAIL"
} | FAIL | 1,307 |
{
"REASONING": [
"The QUESTION asks for the number of RASs to NS5A inhibitors identified.",
"The DOCUMENT states that RASs to NS5A inhibitors (L31M and L31V) were identified in 2 strains out of 25 fully sequenced samples, which is 8%.",
"The ANSWER correctly states '2 strains out of 25 (8%)'.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 359 |
{
"REASONING": [
"The DOCUMENT states that the SARS-CoV-2 genome sequence is most similar to some bat beta-coronaviruses, with the highest being >96% identity.",
"The DOCUMENT mentions speculation about pangolins carrying CoVs closely related to SARS-CoV-2, but it explicitly states that the data to substantiate this is not yet published.",
"The ANSWER claims that pangolin coronaviruses have the highest similarity (>96% identity) to SARS-CoV-2, which is not supported by the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 612 |
{
"REASONING": [
"The DOCUMENT states that 'Parainfluenza 1,2 and 4 viruses were identified only in winter.'",
"The ANSWER correctly lists 'Parainfluenza 1,2 and 4 viruses' as the viruses identified only in winter.",
"There is no additional or contradictory information in the ANSWER compared to the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 603 |
{
"REASONING": [
"The QUESTION asks how Bacillus subtilis can be used as an oral vaccine.",
"The DOCUMENT provides detailed information on the use of recombinant Bacillus subtilis (B. subtilis-RC) as an oral vaccine carrier for inducing mucosal and systemic immune responses against PEDV infection in piglets.",
"The DOCUMENT explains that B. subtilis-RC can deliver antigens to the gastrointestinal tract, protect antigens from degradation, and stimulate immune responses, including the production of specific antibodies and the activation of T lymphocytes.",
"The ANSWER provided is 'recombinant vaccine carrier,' which is a very brief and general term.",
"While the term 'recombinant vaccine carrier' is mentioned in the DOCUMENT, it does not fully capture the detailed mechanisms and benefits described in the DOCUMENT regarding how B. subtilis is used as an oral vaccine."
],
"SCORE": "FAIL"
} | PASS | 753 |
{
"REASONING": [
"The DOCUMENT states that 'More than 50% of patients who suffer from severe CHIKF are over 65 y old, and more than 33% of them die. Most adults who suffer from severe CHIKF have underlying medical conditions.'",
"It also mentions, 'The other group that is disproportionately affected by severe CHIKV is children.'",
"The ANSWER 'children' directly corresponds to the information provided in the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,230 |
{
"REASONING": [
"The QUESTION asks for the G+C content.",
"The ANSWER provided is '38%'.",
"The DOCUMENT states: 'The G + C content was 38%'.",
"The ANSWER matches the information provided in the DOCUMENT.",
"There is no additional or contradictory information in the ANSWER."
],
"SCORE": "PASS"
} | PASS | 1,934 |
{
"REASONING": [
"The QUESTION asks about the confirmed cases for COVID-19 with the intervention of movement restrictions starting on 5th February 2020.",
"The DOCUMENT states that with the intervention from 5 February, the cumulative incidence among passengers with close contact was 102 cases, and among passengers without close contact was 47 cases.",
"The ANSWER provided is '102 and 47 cases, respectively.'",
"The ANSWER directly matches the information provided in the DOCUMENT without adding or contradicting any details."
],
"SCORE": "PASS"
} | PASS | 1,507 |
{
"REASONING": [
"The DOCUMENT states that 'Intestinal IELs are a large and diverse population of lymphoid cells residing within the intestinal epithelial cells (IECs), and forming the intestinal mucosal barrier.'",
"The ANSWER provided is 'lymphoid cells'.",
"The ANSWER is consistent with the information in the DOCUMENT, which specifies that lymphoid cells (specifically IELs) form the intestinal mucosal barrier.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 761 |
{
"REASONING": [
"The QUESTION asks about the specific influenza virus identified in China in 2013.",
"The DOCUMENT mentions that 'a new influenza virus (H7N9) was identified in China in 2013.'",
"The ANSWER provided is 'H7N9'.",
"The ANSWER is directly supported by the information in the DOCUMENT and does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 89 |
{
"REASONING": [
"The DOCUMENT states that hepcidin is a low molecular weight, antimicrobial peptide hormone.",
"The ANSWER provided is 'low molecular weight, antimicrobial peptide hormone'.",
"The ANSWER is directly derived from the DOCUMENT and does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 189 |
{
"REASONING": [
"The DOCUMENT specifies that resources must be identified to protect healthcare workers, develop and deploy rapid testing, improve surveillance, and enact quarantine and isolation of contacts and cases.",
"The ANSWER correctly includes the points about protecting healthcare workers, developing and deploying rapid testing, improving surveillance, and enacting quarantine and isolation of contacts and cases.",
"The ANSWER adds an additional point about providing free healthcare services to all affected individuals, which is not mentioned in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 1,988 |
{
"REASONING": [
"The DOCUMENT states that throat swabs from 42 cases without respiratory infections were included as control samples.",
"These 42 control samples are further broken down into 15 patients with bacterial infections and 27 individuals without active infections.",
"The ANSWER states that 25 control samples were used in the study.",
"This number does not match the total of 42 control samples mentioned in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 227 |
{
"REASONING": [
"The DOCUMENT states that nuclear receptors regulate various biological processes, including homeostasis, differentiation, embryonic development, and organ physiology.",
"The ANSWER correctly includes homeostasis, differentiation, and embryonic development, which are mentioned in the DOCUMENT.",
"The DOCUMENT does not mention 'immune response' as a process regulated by nuclear receptors.",
"The DOCUMENT mentions 'organ physiology' instead of 'immune response'."
],
"SCORE": "FAIL"
} | FAIL | 300 |
{
"REASONING": [
"The QUESTION asks for another case in point.",
"The DOCUMENT provides several examples of cases in point, including the CRISPR/Cas antiviral immune system and the ancient lineage of nucleocytosolic large DNA viruses (NCLDVs).",
"The ANSWER, 'the ancient lineage of nucleocytosolic large DNA viruses (NCLDVs)', is directly mentioned in the DOCUMENT as another case in point.",
"The ANSWER does not introduce new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,844 |
{
"REASONING": [
"The provided answer lists 'displacement, crowded housing, malnutrition, inadequate water, sanitation, and hygiene (WASH) tools' as reasons for susceptibility, which are all mentioned in the DOCUMENT.",
"The provided answer also includes 'lack of access to education' as a reason for susceptibility, which is not mentioned in the DOCUMENT.",
"Including 'lack of access to education' introduces new information that is not supported by the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 1,981 |
{
"REASONING": [
"The QUESTION asks for the Generalized Anxiety Disorder scale scores.",
"The DOCUMENT provides the median [IQR] Generalized Anxiety Disorder scale scores among men vs women as 2.0 [0-6.0] vs 4.0 [1.0-7.0]; P < .001.",
"The ANSWER states the scores as 3.0 [1-7.0] vs 5.0 [2.0-8.0]; P < .001.",
"The scores provided in the ANSWER do not match the scores provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 463 |
{
"REASONING": [
"The provided answer states that a confirmed case is a person with laboratory confirmation of SARS-CoV-2 infection, irrespective of clinical signs and symptoms.",
"The document specifies that the ECDC recommended two separate SARS-CoV-2 RT-PCR tests for confirmation.",
"The provided answer also states that a probable case is a suspect case for whom testing for SARS-CoV-2 was inconclusive or positive using a pan-coronavirus assay.",
"The document confirms this definition for a probable case."
],
"SCORE": "PASS"
} | PASS | 1,770 |
{
"REASONING": [
"The QUESTION asks who released the time series data from after 21st January 2020.",
"The DOCUMENT states: 'The time series data of 2019-nCoV cases in mainland China were initially released by the Wuhan Municipal Health Commission from 10 to 20 January 2020, and later by the National Health Commission of China after 21 January 2020.'",
"The ANSWER provided is: ', and later by the National Health C'.",
"The ANSWER is incomplete but does not contradict the DOCUMENT.",
"The incomplete ANSWER does not provide new information beyond the context provided in the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,909 |
{
"REASONING": [
"The provided answer states that several novel bat coronaviruses were isolated from Chinese horseshoe bats and that the bat SARS-like or SL-CoV-WIV1 was able to use ACE2 from humans, civets, and Chinese horseshoe bats for entry.",
"The DOCUMENT confirms this information in the following passage: 'However, in 2013 several novel bat coronaviruses were isolated from Chinese horseshoe bats and the bat SARS-like or SL-CoV-WIV1 was able to use ACE2 from humans, civets and Chinese horseshoe bats for entry.'",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 626 |
{
"REASONING": [
"The DOCUMENT states that some Yunnan strains such as the WIV1 had no deletions and can use human ACE2 as a cellular entry receptor.",
"The ANSWER claims that the consequence of lack of deletions in Yunnan strains is that they cannot use human ACE2 as a cellular entry receptor.",
"This directly contradicts the information in the DOCUMENT, which indicates that the lack of deletions allows these strains to use human ACE2 as a cellular entry receptor."
],
"SCORE": "FAIL"
} | FAIL | 1,946 |
{
"REASONING": [
"The DOCUMENT states that the symptoms in humans infected with H5N1 include fever, encephalitis, pneumonia, and severe acute respiratory syndrome (SARS).",
"The ANSWER lists the symptoms as fever, encephalitis, pneumonia, and severe acute respiratory distress syndrome (ARDS).",
"The term 'severe acute respiratory syndrome (SARS)' in the DOCUMENT is replaced with 'severe acute respiratory distress syndrome (ARDS)' in the ANSWER.",
"SARS and ARDS are different conditions, and this substitution introduces a discrepancy."
],
"SCORE": "FAIL"
} | FAIL | 133 |
{
"REASONING": [
"The DOCUMENT states that as of 5 March 2020, there were 4,250 cases in the WHO European region.",
"The DOCUMENT also mentions that there were 113 deaths reported among these cases.",
"The ANSWER states that there are 4,250 cases including 120 deaths reported among 38 countries.",
"The number of cases (4,250) in the ANSWER matches the DOCUMENT.",
"The number of deaths (120) in the ANSWER does not match the DOCUMENT, which states 113 deaths."
],
"SCORE": "FAIL"
} | FAIL | 1,795 |
{
"REASONING": [
"The DOCUMENT states that the time from symptom onset to hospitalisation/case isolation was about 3 days longer for locally acquired cases than for imported cases.",
"The ANSWER incorrectly states that the time was about 3 days shorter for locally acquired cases than for imported cases.",
"This directly contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 1,797 |
{
"REASONING": [
"The QUESTION asks for the major viruses mostly responsible for ILI and pneumonia as identified in several studies.",
"The DOCUMENT states: 'Influenza viruses, Respiratory Syncytial viruses (RSV) and Parainfluenza viruses are identified as major viruses mostly responsible for ILI and pneumonia in several studies.'",
"The ANSWER lists 'Influenza viruses, Respiratory Syncytial viruses (RSV) and Parainfluenza viruses', which matches the information provided in the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 584 |
{
"REASONING": [
"The DOCUMENT states that meningitis cases are reportable to the California Department of Public Health (CDPH) within 1 day of identification of etiology.",
"The ANSWER states that meningitis cases should be reported within 2 days of identification.",
"The ANSWER contradicts the information provided in the DOCUMENT."
],
"SCORE": "FAIL"
} | FAIL | 295 |
{
"REASONING": [
"The QUESTION asks about the authors' recent report.",
"The DOCUMENT mentions that the authors recently reported a familial cluster of 2019-nCoV infection in a Shenzhen family with travel history to Wuhan.",
"The ANSWER correctly states that the authors' recent report was on a familial cluster of 2019-nCoV infection in a Shenzhen family with travel history to Wuhan.",
"The ANSWER does not introduce new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,925 |
{
"REASONING": [
"The QUESTION asks how the SARS-CoV gained elevated replication and lung pathogenesis in aged mice.",
"The DOCUMENT states that the SARS-CoV gained elevated replication and lung pathogenesis in aged mice due to six coding genetic mutations associated with mouse adaptation.",
"The ANSWER provided is 'due to six coding genetic mutations associated with mouse adaptation.'",
"The ANSWER is directly taken from the DOCUMENT and does not introduce new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 623 |
{
"REASONING": [
"The DOCUMENT states that 'Symptoms at the point of diagnosis were reported for 31 cases.'",
"The ANSWER '31 cases' directly corresponds to the information provided in the DOCUMENT.",
"There is no additional or contradictory information in the ANSWER compared to the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,780 |
{
"REASONING": [
"The DOCUMENT states that the study includes a comparison between cases detected among travellers from China and cases whose infection was acquired due to subsequent local transmission.",
"The ANSWER accurately reflects this aspect of the study by mentioning the comparison between cases detected among travellers from China and cases whose infection was acquired due to subsequent local transmission.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,766 |
{
"REASONING": [
"The provided answer states that 'FPA is applied as a local search method for SSA.'",
"According to the DOCUMENT, the correct description is that 'SSA is applied as a local search method for FPA.'",
"This is a clear contradiction between the provided answer and the DOCUMENT.",
"The DOCUMENT explicitly describes the FPASSA method as using SSA to improve FPA, not the other way around."
],
"SCORE": "FAIL"
} | FAIL | 525 |
{
"REASONING": [
"The QUESTION asks where certain activities take place.",
"The DOCUMENT states that 'these activities take place in various subcellular compartments and are differentially regulated during infection.'",
"The ANSWER provided is 'in various subcellular compartments.'",
"The ANSWER directly matches the information provided in the DOCUMENT without adding or contradicting any details."
],
"SCORE": "PASS"
} | PASS | 1,829 |
{
"REASONING": [
"The DOCUMENT states that PEDV spreads primarily through fecal-oral contact.",
"The ANSWER provided is 'fecal-oral contact'.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 373 |
{
"REASONING": [
"The DOCUMENT states that 'we assumed that the transmissibility of asymptomatic infection was 0.5 times that of symptomatic infection (κ = 0.5), which was the similar value as influenza.'",
"The ANSWER correctly reflects this assumption by stating '0.5 times that of symptomatic infection (κ = 0.5), which was the similar value as influenza.'",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,493 |
{
"REASONING": [
"The DOCUMENT states that 'in the earliest phase of the outbreak the basic reproductive number was estimated to be around 2.2, assuming a mean serial interval of 7.5 days.'",
"The ANSWER provided is '2.2'.",
"The ANSWER does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,534 |
{
"REASONING": [
"The QUESTION asks for the number of patients analyzed in the study.",
"The DOCUMENT states, 'Two hundred patients with suspected CAP were analyzed.'",
"The ANSWER provided is 'Two hundred'.",
"The ANSWER matches the information given in the DOCUMENT and does not introduce any new information or contradict the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 406 |
{
"REASONING": [
"The DOCUMENT states that the average delays between infection and illness onset are around 5-6 days, with an upper limit of around 11-14 days.",
"The DOCUMENT also mentions that delays from illness onset to laboratory confirmation added a further 10 days on average.",
"The ANSWER accurately reflects these points without adding new information or contradicting the DOCUMENT."
],
"SCORE": "PASS"
} | PASS | 1,538 |