--- base_model: Writer/Palmyra-Med-70B-32K language: - en license: other license_name: writer-open-model-license license_link: https://writer.com/legal/open-model-license/ tags: - instruct - finetune - DPO - distillation - heathcare - medical - clinical - med - lifescience - Pharmaceutical - Pharma - Enterprise LLM - Enterprise - Enterprise ready - mlc-ai - MLC-Weight-Conversion extra_gated_prompt: By clicking "Agree", you agree to the [License Agreement](https://writer.com/legal/open-model-license/) and acknowledge Writer's [Privacy Policy](https://writer.com/legal/acceptable-use/). extra_gated_fields: Name: text Email: text Organization or Affiliation: text Receive email updates and promotions on Writer products, services, and research?: type: select options: - 'Yes' - 'No' I acknowledge that this model is for non-commercial use only unless I acquire a separate license from Writer: checkbox widget: - example_title: Palmyra-Med-70B-32k messages: - role: system content: You are a highly knowledgeable and experienced expert in the healthcare and biomedical field, possessing extensive medical knowledge and practical expertise. - role: user content: Does danzhi Xiaoyao San ameliorate depressive-like behavior by shifting toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase? output: text: Danzhi Xiaoyao San (DXS) exhibited significant antidepressant-like effects in rats subjected to chronic unpredictable mild stress (CUMS), a commonly used model for inducing depressive-like behavior. The administration of DXS led to a notable reduction in the activity of indoleamine 2,3-dioxygenase (IDO) in the hippocampus. This reduction in IDO activity is crucial because IDO is an enzyme that catalyzes the degradation of tryptophan into kynurenine (Kyn), thereby diverting tryptophan away from the serotonin (5-HT) synthesis pathway. By downregulating IDO, DXS effectively shifts the balance of tryptophan metabolism towards increased serotonin production, thereby enhancing the availability of serotonin. This shift in the Kyn/5-HT pathway favoring serotonin is likely a key mechanism underlying the antidepressant effects observed with DXS treatment. Enhanced serotonin levels in the hippocampus are associated with improved mood and reduction of depressive symptoms, suggesting that DXS could be a promising therapeutic agent for managing depression. model-index: - name: Palmyra-Med-70B-32k results: [] --- --- library_name: mlc-llm base_model: Writer/Palmyra-Med-70B-32K tags: - mlc-llm - web-llm --- # codegood/Palmyra-Med-70B-32K-q4f16_1-MLC This is the [Palmyra-Med-70B-32K](https://huggingface.co/Writer/Palmyra-Med-70B-32K) model in MLC format `q4f16_1`. The conversion was done using the [MLC-Weight-Conversion](https://huggingface.co/spaces/mlc-ai/MLC-Weight-Conversion) space. The model can be used for projects [MLC-LLM](https://github.com/mlc-ai/mlc-llm) and [WebLLM](https://github.com/mlc-ai/web-llm). ## Example Usage Here are some examples of using this model in MLC LLM. Before running the examples, please install MLC LLM by following the [installation documentation](https://llm.mlc.ai/docs/install/mlc_llm.html#install-mlc-packages). ### Chat In command line, run ```bash mlc_llm chat HF://mlc-ai/codegood/Palmyra-Med-70B-32K-q4f16_1-MLC ``` ### REST Server In command line, run ```bash mlc_llm serve HF://mlc-ai/codegood/Palmyra-Med-70B-32K-q4f16_1-MLC ``` ### Python API ```python from mlc_llm import MLCEngine # Create engine model = "HF://mlc-ai/codegood/Palmyra-Med-70B-32K-q4f16_1-MLC" engine = MLCEngine(model) # Run chat completion in OpenAI API. for response in engine.chat.completions.create( messages=[{"role": "user", "content": "What is the meaning of life?"}], model=model, stream=True, ): for choice in response.choices: print(choice.delta.content, end="", flush=True) print("\n") engine.terminate() ``` ## Documentation For more information on MLC LLM project, please visit our [documentation](https://llm.mlc.ai/docs/) and [GitHub repo](http://github.com/mlc-ai/mlc-llm).